Unresponsiveness of specific T cells to IL-12 is associated with active cutaneous leishmaniasis owing to Leishmania guyanensis

Scandinavian Journal of Immunology

Volumn 54, Issue 3, 2001, Pages 335-339

  Bourreau, E ^a   Prevot G ^a   Pradinaud, R ^b   Launois, P ^a,c  

^a Immunologie des Leishmanies   (Guyana)

^b Centre Hospitalier Andree Rosemon   (Guyana)

^c INSTITUT PASTEUR DE LA GUYANE   (French Guiana)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; PARASITE ANTIGEN;

ARTICLE; CELL SPECIFICITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; LEISHMANIA; LYMPHOCYTE FUNCTION; MONONUCLEAR CELL; PRIORITY JOURNAL; PROMASTIGOTE; SKIN LEISHMANIASIS; T LYMPHOCYTE; VEIN PUNCTURE;

ANIMALS; ANTIGENS, PROTOZOAN; CELLS, CULTURED; HUMANS; INTERLEUKIN-12; INTERLEUKIN-13; LEISHMANIA GUYANENSIS; LEISHMANIASIS, CUTANEOUS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0035720557     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00981.x     Document Type: Article

References (10)

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4. Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness
5. Recognition of protozoan parasite antigens by murine T lymphocytes
6. Down-regulation of Th1 response in early human cutaneous leishmaniasis
7. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon-γ independent mechanism
8. + T cells in BALB/c mice infected with Leishmania major instructs Th2 cell development and susceptibility to infection
9. IL-4 deficient Balb/c mice resist infection with Leishmania major
10. Susceptibility to Leishmania major infection in IL-4 deficient mice