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Volumn 134, Issue 2, 2003, Pages 206-212

Selective activation of PPARγ inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator

Author keywords

[No Author keywords available]

Indexed keywords

15D PGJ2; 15DEOXY DELTA12,14 PROSTAGLANDIN J2; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; TISSUE PLASMINOGEN ACTIVATOR; TROGLITAZONE; UNCLASSIFIED DRUG; 15 DEOXYPROSTAGLANDIN J2; 15-DEOXYPROSTAGLANDIN J2; 2,4 THIAZOLIDINEDIONE DERIVATIVE; CELL RECEPTOR; CHROMAN DERIVATIVE; DRUG DERIVATIVE; INTEGRIN; MATRIX METALLOPROTEINASE; PROSTAGLANDIN D2; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

EID: 0042829213     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1067/msy.2003.221     Document Type: Article
Times cited : (22)

References (25)
  • 3
    • 0031426723 scopus 로고    scopus 로고
    • Pancreaticoduodenectomy for pancreatic adenocarcinoma: Postoperative adjuvant chemoradiation improves survival. A prospective single-institution experience
    • Yeo CJ, Abrams RA, Grochow LB, Sohn TA, Ord SE, Hruban RH, et al. Pancreaticoduodenectomy for pancreatic adenocarcinoma: postoperative adjuvant chemoradiation improves survival. A prospective single-institution experience. Ann Surg 1997;225:621-36.
    • (1997) Ann Surg , vol.225 , pp. 621-636
    • Yeo, C.J.1    Abrams, R.A.2    Grochow, L.B.3    Sohn, T.A.4    Ord, S.E.5    Hruban, R.H.6
  • 4
    • 0033549875 scopus 로고    scopus 로고
    • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA
    • Wang W, Abbruzzese JL, Evans DB, Chiao PJ. Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. Oncogene 1999;18:4554-63.
    • (1999) Oncogene , vol.18 , pp. 4554-4563
    • Wang, W.1    Abbruzzese, J.L.2    Evans, D.B.3    Chiao, P.J.4
  • 6
    • 0032485048 scopus 로고    scopus 로고
    • The plasminogen activator system in pancreas cancer: Role of t-PA in the invasive potential in vitro
    • Paciucci R, Tora M, Diaz VM, Real FX. The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro. Oncogene 1998;16:625-33.
    • (1998) Oncogene , vol.16 , pp. 625-633
    • Paciucci, R.1    Tora, M.2    Diaz, V.M.3    Real, F.X.4
  • 8
    • 0032173439 scopus 로고    scopus 로고
    • The nuclear receptor PPARgammaCbigger than fat
    • Kliewer SA, Willson TM. The nuclear receptor PPARgammaCbigger than fat. Curr Opin Genet Dev 1998;8:576-81.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 576-581
    • Kliewer, S.A.1    Willson, T.M.2
  • 9
    • 0036934710 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells
    • Hashimoto K, Ethridge RT, Evers BM. Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. Int J Gastrointest Cancer 2002;32:7-22.
    • (2002) Int J Gastrointest Cancer , vol.32 , pp. 7-22
    • Hashimoto, K.1    Ethridge, R.T.2    Evers, B.M.3
  • 10
    • 0034540805 scopus 로고    scopus 로고
    • PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells
    • Elnemr A, Ohta T, Iwata K, Ninomia I, Fushida S, Nishimura G, et al. PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells. Int J Oncol 2000;17:1157-64.
    • (2000) Int J Oncol , vol.17 , pp. 1157-1164
    • Elnemr, A.1    Ohta, T.2    Iwata, K.3    Ninomia, I.4    Fushida, S.5    Nishimura, G.6
  • 11
    • 0037183989 scopus 로고    scopus 로고
    • Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells
    • Wang Q, Wang X, Hernandez A, Hellmich MR, Gatalica Z, Evers BM. Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells. J Biol Chem 2002;277:36602-10.
    • (2002) J Biol Chem , vol.277 , pp. 36602-36610
    • Wang, Q.1    Wang, X.2    Hernandez, A.3    Hellmich, M.R.4    Gatalica, Z.5    Evers, B.M.6
  • 12
    • 0031858241 scopus 로고    scopus 로고
    • Signal transduction mechanisms in neurotensin-mediated cellular regulation
    • Ehlers RA, 2nd, Bonnor RM, Wang X, Hellmich MR, Evers BM. Signal transduction mechanisms in neurotensin-mediated cellular regulation. Surgery 1998;124:239-46; discussion 46-7.
    • (1998) Surgery , vol.124 , pp. 239-246
    • Ehlers R.A. II1    Bonnor, R.M.2    Wang, X.3    Hellmich, M.R.4    Evers, B.M.5
  • 13
    • 0034306992 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells
    • Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y. Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells. Cancer Res 2000;60:5558-64.
    • (2000) Cancer Res , vol.60 , pp. 5558-5564
    • Motomura, W.1    Okumura, T.2    Takahashi, N.3    Obara, T.4    Kohgo, Y.5
  • 15
    • 0037473753 scopus 로고    scopus 로고
    • Activation of PPARgamma increases PTEN expression in pancreatic cancer cells
    • Farrow B, Mark Evers B. Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. Biochem Biophys Res Commun 2003;301:50-3.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 50-53
    • Farrow, B.1    Mark Evers, B.2
  • 16
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elsmer E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, et al. Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 1998;95:8806-11.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8806-8811
    • Elsmer, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6
  • 17
    • 0031671246 scopus 로고    scopus 로고
    • Differentiation and reversal of malignant changes in colon cancer through PPARgamma
    • Sarraf P, Mueller E, Jones D, King FJ, DeAngelo DJ, Partridge JB, et al. Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nat Med 1998;4:1046-52.
    • (1998) Nat Med , vol.4 , pp. 1046-1052
    • Sarraf, P.1    Mueller, E.2    Jones, D.3    King, F.J.4    DeAngelo, D.J.5    Partridge, J.B.6
  • 18
    • 0343855442 scopus 로고    scopus 로고
    • Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer
    • Mueller E, Smith M, Sarraf P, Kroll T, Aiyer A, Kaufman DS, et al. Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. Proc Natl Acad Sci U S A 2000;97:10990-5.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10990-10995
    • Mueller, E.1    Smith, M.2    Sarraf, P.3    Kroll, T.4    Aiyer, A.5    Kaufman, D.S.6
  • 19
    • 0037150792 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: Associated with iNOS and COX-2
    • Kim EJ, Kwon KJ, Park JY, Lee SH, Moon CH, Baik EJ. Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. Brain Res 2002;941:1-10.
    • (2002) Brain Res , vol.941 , pp. 1-10
    • Kim, E.J.1    Kwon, K.J.2    Park, J.Y.3    Lee, S.H.4    Moon, C.H.5    Baik, E.J.6
  • 20
    • 14444281382 scopus 로고    scopus 로고
    • Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma
    • Young PW, Buckle DR, Cantello BC, Chapman H, Clapham JC, Coyle PJ, et al. Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma. J Pharmacol Exp Ther 1998;284:751-9.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 751-759
    • Young, P.W.1    Buckle, D.R.2    Cantello, B.C.3    Chapman, H.4    Clapham, J.C.5    Coyle, P.J.6
  • 21
    • 0036245330 scopus 로고    scopus 로고
    • Differentiating members of the thiazolidinedione class: A focus on safety
    • Lebovitz HE. Differentiating members of the thiazolidinedione class: a focus on safety. Diabetes Metab Res Rev 2002;18 Suppl 2:S23-9.
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.2 SUPPL.
    • Lebovitz, H.E.1
  • 22
    • 0036176560 scopus 로고    scopus 로고
    • Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells
    • Diaz VM, Planaguma J, Thomson TM, Reventos J, Paciucci R. Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells. Gastroenterology 2002;122:806-19.
    • (2002) Gastroenterology , vol.122 , pp. 806-819
    • Diaz, V.M.1    Planaguma, J.2    Thomson, T.M.3    Reventos, J.4    Paciucci, R.5
  • 23
    • 0035117608 scopus 로고    scopus 로고
    • Production of matrix metalloproteinase-9 in CaCO2 cells in response to inflammatory stimuli
    • Gan X, Wong B, Wright SD, Cai TQ. Production of matrix metalloproteinase-9 in CaCO2 cells in response to inflammatory stimuli. J Interferon Cytokine Res 2001;21:93-8.
    • (2001) J Interferon Cytokine Res , vol.21 , pp. 93-98
    • Gan, X.1    Wong, B.2    Wright, S.D.3    Cai, T.Q.4
  • 24
    • 0035865438 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: Clinicopathologic and prognostic significance of matrilysin expression
    • Yamamoto H, Itoh F, Iku S, Adachi Y, Fukushima H, Sasaki S, et al. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression. J Clin Oncol 2001;19:1118-27.
    • (2001) J Clin Oncol , vol.19 , pp. 1118-1127
    • Yamamoto, H.1    Itoh, F.2    Iku, S.3    Adachi, Y.4    Fukushima, H.5    Sasaki, S.6
  • 25
    • 0027237424 scopus 로고
    • Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
    • Berlin C, Berg EL, Briskin MJ, Andrew DP, Kilshaw PJ, Holzmann B, et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993;74:185-5.
    • (1993) Cell , vol.74 , pp. 185-185
    • Berlin, C.1    Berg, E.L.2    Briskin, M.J.3    Andrew, D.P.4    Kilshaw, P.J.5    Holzmann, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.