Correction of an enzyme trafficking defect in hereditary kidney stone disease in vitro

Biochemical Journal

Volumn 374, Issue 1, 2003, Pages 79-87

  Lumb, Michael J ^a   Birdsey, Graeme M ^a   Danpure, Christopher J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Alanine:glyoxylate aminotransferase; Enzyme trafficking defect; Kidney stone disease; Mitochondrial protein targeting; Peroxisomal protein targeting; Primary hyperoxaluria type 1

Indexed keywords

BIOCHEMISTRY; CELLS; DIMERIZATION; DISEASES; MUTAGENESIS; PROTEINS; STRUCTURE (COMPOSITION);

MITOCHONDRIA;

ENZYME KINETICS;

ALANINE GLYOXYLATE AMINOTRANSFERASE; GLYCEROL; LEUCINE; MITOCHONDRIAL PROTEIN; PROLINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DIMERIZATION; ENZYME DEFECT; ENZYME LOCALIZATION; GENE MUTATION; GENE TARGETING; GENETIC DISORDER; GENETIC POLYMORPHISM; HYPEROXALURIA; LIVER CELL; LOW TEMPERATURE PROCEDURES; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXALOSIS 1; PEROXISOME; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN TRANSPORT; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY;

ALLELES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME STABILITY; GENE THERAPY; HEPATOCYTES; HUMANS; HYPEROXALURIA, PRIMARY; KIDNEY CALCULI; MITOCHONDRIA; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINANT PROTEINS; THERMODYNAMICS; TRANSAMINASES; TRANSFECTION; VARIATION (GENETICS);

ANIMALIA;

EID: 0042827948     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030371     Document Type: Article

References (42)

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