메뉴 건너뛰기




Volumn 21, Issue 9, 2003, Pages 1657-1662

Peroxisome proliferator-activated receptor-γPro12Ala polymorphism and the association with blood pressure in type 2 diabetes: Skaraborg hypertension and diabetes project

Author keywords

Association study; Blood pressure; Diabetes mellitus; Genetics; Hypertension; Peroxisorne proliferator activated receptor ; Polyrnorphism; Primary care; Pro12Ala

Indexed keywords

HEMOGLOBIN A1C; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL;

EID: 0042733635     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200309000-00014     Document Type: Article
Times cited : (56)

References (19)
  • 1
    • 0033998334 scopus 로고    scopus 로고
    • The PPARs: From orphan receptors to drug discovery
    • Willson T, Brown P, Sternbach D, Henke B. The PPARs: from orphan receptors to drug discovery. J Med Chem 2000; 43:527-550.
    • (2000) J Med Chem , vol.43 , pp. 527-550
    • Willson, T.1    Brown, P.2    Sternbach, D.3    Henke, B.4
  • 2
    • 0030746580 scopus 로고    scopus 로고
    • Troglitazone
    • Spencer C, Markham A. Troglitazone. Drugs 1997; 54:89-101.
    • (1997) Drugs , vol.54 , pp. 89-101
    • Spencer, C.1    Markham, A.2
  • 4
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn J, Klannemark M, Lindgren C, Vohl MC, Nemesh J, et al. The common PPARγ. Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 2000; 26:76-80.
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.2    Klannemark, M.3    Lindgren, C.4    Vohl, M.C.5    Nemesh, J.6
  • 5
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitition in PPAR γ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, et al. A Pro12Ala substitition in PPAR γ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998; 3:284-287.
    • (1998) Nat Genet , vol.3 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3    Pihlajamaki, J.4    Mykkanen, L.5    Kuusisto, J.6
  • 7
    • 0033060302 scopus 로고    scopus 로고
    • Pro12Aia substitution in the peroxisome proliferator-activated receptor-γ2 is not associated with type 2 diabetes
    • Mancini FP, Vaccaro O, Sabatino L, Tufano A, Rivellese AA, Riccardi G, et al. Pro12Aia substitution in the peroxisome proliferator-activated receptor-γ2 is not associated with type 2 diabetes. Diabetes 1999; 48:1466-1468.
    • (1999) Diabetes , vol.48 , pp. 1466-1468
    • Mancini, F.P.1    Vaccaro, O.2    Sabatino, L.3    Tufano, A.4    Rivellese, A.A.5    Riccardi, G.6
  • 8
    • 0035062772 scopus 로고    scopus 로고
    • A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-γ2 is associated with combined hyperlipidaemia in obesity
    • Swarbrick M, Chapman ML, McQuillan B, Hung J, Thompson P, Beilby J. A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-γ2 is associated with combined hyperlipidaemia in obesity. Eur J Endocrinol 2001; 144:277-282.
    • (2001) Eur J Endocrinol , vol.144 , pp. 277-282
    • Swarbrick, M.1    Chapman, M.L.2    McQuillan, B.3    Hung, J.4    Thompson, P.5    Beilby, J.6
  • 9
    • 0035093082 scopus 로고    scopus 로고
    • Effect on the peroxisome proliferator-activated receptor gamma pro12ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds
    • Hasstedt SJ, Ren OF, Teng K, Elbein SC. Effect on the peroxisome proliferator-activated receptor gamma pro12ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds. J Clin Endocrinol Metab 2001; 86:536-541.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 536-541
    • Hasstedt, S.J.1    Ren, O.F.2    Teng, K.3    Elbein, S.C.4
  • 10
    • 0034745184 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ2 Pro12Ala variant. Association with type 2 diabetes and trait differences
    • Douglas J, Erdos M, Watanabe R, Braun A, Johnston C, Oeth P, et al. The peroxisome proliferator-activated receptor-γ2 Pro12Ala variant. Association with type 2 diabetes and trait differences. Diabetes 2001; 50:886-890.
    • (2001) Diabetes , vol.50 , pp. 886-890
    • Douglas, J.1    Erdos, M.2    Watanabe, R.3    Braun, A.4    Johnston, C.5    Oeth, P.6
  • 13
    • 0033086233 scopus 로고    scopus 로고
    • Differences in treatment and metabolic abnormalities between normo- and hypertensive patients with type 2 diabetes
    • Östgren CJ, Lindblad U, Bøg-Hansen E, Ranstam J, Melander A, Råstam L. Differences in treatment and metabolic abnormalities between normo- and hypertensive patients with type 2 diabetes. Diabetes Obesity Metab 1999; 1:105-112.
    • (1999) Diabetes Obesity Metab , vol.1 , pp. 105-112
    • Östgren, C.J.1    Lindblad, U.2    Bøg-Hansen, E.3    Ranstam, J.4    Melander, A.5    Råstam, L.6
  • 14
    • 0043223764 scopus 로고
    • Stockholm: National Board of Health and Welfare
    • National Board of Health and Welfare, Drug Information Committee. Treatment of Mild Hypertension. Stockholm: National Board of Health and Welfare; 1987.
    • (1987) Treatment of Mild Hypertension
  • 15
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 16
    • 0030994947 scopus 로고    scopus 로고
    • The homeostasis model in the San Antonio Heart Study
    • Haffner S, Miettinen H, Stern M. The homeostasis model in the San Antonio Heart Study. Diabetes Care 1997; 20:1087-1092.
    • (1997) Diabetes Care , vol.20 , pp. 1087-1092
    • Haffner, S.1    Miettinen, H.2    Stern, M.3
  • 17
    • 0034607051 scopus 로고    scopus 로고
    • Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis
    • Masugi J, Tamori Y, Mori H, Koike T, Kasuga M. Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-gamma 2 on thiazolidinedione-induced adipogenesis. Biochem Biophys Res Commun 2000; 268:178-182.
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 178-182
    • Masugi, J.1    Tamori, Y.2    Mori, H.3    Koike, T.4    Kasuga, M.5
  • 18
    • 0034633847 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activators downregulate angiotensin II type 1 receptors in vascular smooth muscle cells
    • Takeda K, Ichiki T, Tokunou T, Funakoshi Y, Iino N, Hirano K, et al. Peroxisome proliferator-activated receptor γ activators downregulate angiotensin II type 1 receptors in vascular smooth muscle cells. Circulation 2000; 102:1834-1839.
    • (2000) Circulation , vol.102 , pp. 1834-1839
    • Takeda, K.1    Ichiki, T.2    Tokunou, T.3    Funakoshi, Y.4    Iino, N.5    Hirano, K.6
  • 19
    • 0034989969 scopus 로고    scopus 로고
    • Transcriptional supression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-γ2 in vascular smooth muscle cells
    • Sugawara A, Takeuchi K, Uruno A, Ikeda Y, Arima S, Kudo M, et al. Transcriptional supression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-γ2 in vascular smooth muscle cells. Endocrinology 2001; 142:3125-3134.
    • (2001) Endocrinology , vol.142 , pp. 3125-3134
    • Sugawara, A.1    Takeuchi, K.2    Uruno, A.3    Ikeda, Y.4    Arima, S.5    Kudo, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.