Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8)

FASEB Journal

Volumn 17, Issue 11, 2003, Pages 1380-1391

  Georget, Marie ^a   Mateo, Philippe ^a   Vandecasteele, Grégoire ^a   Lipskaia, Larissa ^b   Defer, Nicole ^b   Hanoune, Jacques ^b   Hoerter, Jacqueline ^a   Lugnier, Claire ^c   Fischmeister, Rodolphe ^a,d  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d INSERM   (France)

Author keywords

adrenoceptors; CAMP; Compartmentation; Isolated heart; L type Ca2+ current; Muscarinic receptors; Muscarinic receptors phosphodiesterase; Transgenic mouse

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; CARBACHOL; CYCLIC AMP; CYCLIC AMP PHOSPHODIESTERASE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ISOENZYME; ISOPRENALINE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE IV; SPLEEN EXONUCLEASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HUMAN; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE;

1-METHYL-3-ISOBUTYLXANTHINE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CARBACHOL; CELL COMPARTMENTATION; CELLS, CULTURED; CYCLIC AMP; ELECTRIC CONDUCTIVITY; GENE EXPRESSION; HEART; HUMANS; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MUSCARINIC AGONISTS; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHOSPHODIESTERASE INHIBITORS;

ANIMALIA; MUS MUSCULUS;

EID: 0042710790     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.02-0784com     Document Type: Article

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