In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of former prisoners of war with and without posttraumatic stress disorder

Journal of Neuropsychiatry and Clinical Neurosciences

Volumn 15, Issue 3, 2003, Pages 367-370

  Brown, Shelley ^b   Freeman, Thomas ^a   Kimbrell, Tim ^b   Cardwell, David ^b   Komoroski, Richard ^b  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; N ACETYLASPARTIC ACID;

AGED; ARTICLE; BRAIN; BRAIN METABOLISM; BRAIN SIZE; CLINICAL ARTICLE; HUMAN; MALE; MENTAL DISEASE; NEUROPSYCHOLOGY; NEURORADIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PRISONER; PROTON NUCLEAR MAGNETIC RESONANCE; SOLDIER; SYMPTOMATOLOGY; TEMPORAL LOBE; WAR;

EID: 0042662756     PISSN: 08950172     EISSN: None     Source Type: Journal    
DOI: 10.1176/jnp.15.3.367     Document Type: Article

References (14)

1. Sutker PB, Allain AN, Winstead DK: Psychopathology and psychiatric diagnoses of World War II Pacific theater prisoner of war survivors and combat veterans. Am J Psychiatry 1993; 150:240-245
2. Sutker PB, Galina ZH, West JA, et al: Trauma induced weight loss and cognitive deficits among former prisoners of war. J Consult Clin Psychol 1990; 58:323-328
3. Sulway MR, Broe GA, Creasey H, et al: Are malnutrition and stress risk factors for accelerated cognitive decline? a prisoner of war study. Neurology 1996; 46:650-655
4. Bremner JD, Randall P, Scott TM, et al: MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry 1995; 152:973-981
5. DeBellis MD, Keshavan MS, Spencer S, et al: N-acetylaspartate concentration in the anterior cingulate of maltreated children and adolescents with PTSD. Am J Psychiatry 2000; 157:1175-1177
6. Bremner JD, Innis RB, Ng CK, et al: Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. Arch Gen Psychiatr 1997; 54:246-254
7. Zubieta JK, Chinitz JA, Lombardi U, et al: Medial frontal cortex involvement in PTSD symptoms: a SPECT study. J Psychiatr Res 1999; 33:259-264
8. Freeman TW, Cardwell D, Karson CN, et al: In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat-related posttraumatic stress disorder. Mag Reson Med 1998; 40:66-71
9. Schuff M, Marmar CR, Weiss DS, et al: Reduced hippocampal volume and N-acetylaspartate in posttraumatic stress disorder. Ann NY Acad Sci 1997; 821:516-520
10. Brooks WM, Sabet A, Sibbitt WL, et al: Neurochemistry of brain lesions determined by spectroscopic imaging in systemic lupus erythematosus. J Rheumatol 1997; 24:2323-2329
11. Brooks WM, Jung RE, Ford CC, et al: Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus. J Rheumatol 1999; 26:81-85
12. Weathers F, Keane T, Davidson JR: Clinician-administered PTSD scale: a review of the first 10 years of research. Depress Anxiety 2001; 13:132-156
13. First MB, Spitzer RL, Gibbon M, et al: Structured Clinical Interview for DSM-IV Axis I Disorders (SCID). New York, New York State Psychiatric Institute, Biometrics Research, 1995
14. Bremner JD: Does stress damage the brain? Biol Psychol 1999; 45:797-805