Arabinosylcytosine downregulates thymidine kinase and induces cross-resistance to zidovudine in T-lymphoid cells

Biochemical and Biophysical Research Communications

Volumn 307, Issue 3, 2003, Pages 564-568

  Han, Tieran ^a   Fernandez, Marilyn ^a   Sarkar, Malancha ^a   Agarwal, Ram P ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Arabinosylcytosine; Azidothymidine resistance; Cross resistance; Deoxycytidine kinase; Thymidine kinase 1; Thymidine kinase 2

Indexed keywords

CYTARABINE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; PROTEIN; THYMIDINE KINASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS RESISTANCE; DOWN REGULATION; DRUG ACCUMULATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOID CELL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0042627913     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01232-4     Document Type: Article

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