메뉴 건너뛰기




Volumn 19, Issue 5, 2003, Pages 333-344

Effect of intragranular porosity on compression behaviour of and drug release from reservoir pellets

Author keywords

Deformation; Densification; Drug release; Extrusion spheronisation; Intragranular porosity; Reservoir pellet

Indexed keywords

CELLULOSE; COATINGS; COMPACTION; CRYSTALLINE MATERIALS; DEFORMATION; POROSITY; SPRAYING;

EID: 0042626022     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(03)00106-4     Document Type: Article
Times cited : (49)

References (37)
  • 1
    • 0027984295 scopus 로고
    • The strength and compaction of millispheres. The design of a controlled-release drug delivery system for ibuprofen in the form of a tablet comprising compacted polymer-coated millispheres
    • Aulton M.E., Dyer A.M., Khan K.A. The strength and compaction of millispheres. The design of a controlled-release drug delivery system for ibuprofen in the form of a tablet comprising compacted polymer-coated millispheres. Drug Dev. Ind. Pharm. 20:1994;3069-3104.
    • (1994) Drug Dev. Ind. Pharm. , vol.20 , pp. 3069-3104
    • Aulton, M.E.1    Dyer, A.M.2    Khan, K.A.3
  • 2
    • 0030601804 scopus 로고    scopus 로고
    • Compression of enteric-coated pellets to disintegrating tablets
    • Beckert T.E., Lehmann K., Schmidt P.C. Compression of enteric-coated pellets to disintegrating tablets. Int. J. Pharm. 143:1996;13-23.
    • (1996) Int. J. Pharm. , vol.143 , pp. 13-23
    • Beckert, T.E.1    Lehmann, K.2    Schmidt, P.C.3
  • 4
    • 0037018965 scopus 로고    scopus 로고
    • The influence of pellet shape and surface properties on the drug release from uncoated and coated pellets
    • Chopra R., Alderborn G., Podczeck F., Newton J.M. The influence of pellet shape and surface properties on the drug release from uncoated and coated pellets. Int. J. Pharm. 239:2002;171-178.
    • (2002) Int. J. Pharm. , vol.239 , pp. 171-178
    • Chopra, R.1    Alderborn, G.2    Podczeck, F.3    Newton, J.M.4
  • 5
    • 0000948063 scopus 로고
    • A method of assessing numerical and percentage values to the degree of roundness of sand grains
    • Cox E.P. A method of assessing numerical and percentage values to the degree of roundness of sand grains. J. Paleontol. 1:1927;179-183.
    • (1927) J. Paleontol. , vol.1 , pp. 179-183
    • Cox, E.P.1
  • 6
    • 0027494787 scopus 로고
    • The use of air permeametry for the assessment of external surface area and sphericity of pelletized granules
    • Eriksson M., Nyström C., Alderborn G. The use of air permeametry for the assessment of external surface area and sphericity of pelletized granules. Int. J. Pharm. 99:1993;197-207.
    • (1993) Int. J. Pharm. , vol.99 , pp. 197-207
    • Eriksson, M.1    Nyström, C.2    Alderborn, G.3
  • 8
    • 0037148678 scopus 로고    scopus 로고
    • Production of inert cushioning beads: Effect of excipients on the physicomechanical properties of freeze-dried beads containing microcrystalline cellulose produced by extrusion-spheronization
    • Habib Y.S., Augsburger L.L., Shangraw R.F. Production of inert cushioning beads: effect of excipients on the physicomechanical properties of freeze-dried beads containing microcrystalline cellulose produced by extrusion-spheronization. Int. J. Pharm. 233:2002;67-83.
    • (2002) Int. J. Pharm. , vol.233 , pp. 67-83
    • Habib, Y.S.1    Augsburger, L.L.2    Shangraw, R.F.3
  • 9
    • 0032445941 scopus 로고    scopus 로고
    • Tableting of controlled release multiparticulates, the effect of millisphere size and protective overcoating
    • Haslam J.L., Forbes A.E., Rork G.S., Pipkin T.L., Slade D.A., Khossravi D. Tableting of controlled release multiparticulates, the effect of millisphere size and protective overcoating. Int. J. Pharm. 173:1998;233-242.
    • (1998) Int. J. Pharm. , vol.173 , pp. 233-242
    • Haslam, J.L.1    Forbes, A.E.2    Rork, G.S.3    Pipkin, T.L.4    Slade, D.A.5    Khossravi, D.6
  • 11
    • 0345676542 scopus 로고    scopus 로고
    • The effect of wax on compaction of microcrystalline cellulose beads made by extrusion and spheronization
    • Iloañusi N.O., Schwartz J.B. The effect of wax on compaction of microcrystalline cellulose beads made by extrusion and spheronization. Drug Dev. Ind. Pharm. 24:1998;37-44.
    • (1998) Drug Dev. Ind. Pharm. , vol.24 , pp. 37-44
    • Iloañusi, N.O.1    Schwartz, J.B.2
  • 12
    • 0029019149 scopus 로고
    • The effect of water content on the porosity and liquid saturation of extruded cylinders
    • Jerwanska E., Alderborn G., Newton J.M., Nyström C. The effect of water content on the porosity and liquid saturation of extruded cylinders. Int. J. Pharm. 121:1995;65-71.
    • (1995) Int. J. Pharm. , vol.121 , pp. 65-71
    • Jerwanska, E.1    Alderborn, G.2    Newton, J.M.3    Nyström, C.4
  • 13
    • 0029982182 scopus 로고    scopus 로고
    • Degree of pellet deformation during compaction and its relationship to the tensile strength of tablets formed of microcrystalline cellulose pellets
    • Johansson B., Alderborn G. Degree of pellet deformation during compaction and its relationship to the tensile strength of tablets formed of microcrystalline cellulose pellets. Int. J. Pharm. 132:1996;207-220.
    • (1996) Int. J. Pharm. , vol.132 , pp. 207-220
    • Johansson, B.1    Alderborn, G.2
  • 14
    • 0034761360 scopus 로고    scopus 로고
    • The effect of shape and porosity on the compression behaviour and tablet forming ability of granular materials formed from microcrystalline cellulose
    • Johansson B., Alderborn G. The effect of shape and porosity on the compression behaviour and tablet forming ability of granular materials formed from microcrystalline cellulose. Eur. J. Pharm. Biopharm. 52:2001;347-357.
    • (2001) Eur. J. Pharm. Biopharm. , vol.52 , pp. 347-357
    • Johansson, B.1    Alderborn, G.2
  • 15
    • 0028872408 scopus 로고
    • Compression behaviour and compactability of microcrystalline cellulose pellets in relationship to their pore structure and mechanical properties
    • Johansson B., Wikberg M., Ek R., Alderborn G. Compression behaviour and compactability of microcrystalline cellulose pellets in relationship to their pore structure and mechanical properties. Int. J. Pharm. 117:1995;57-73.
    • (1995) Int. J. Pharm. , vol.117 , pp. 57-73
    • Johansson, B.1    Wikberg, M.2    Ek, R.3    Alderborn, G.4
  • 16
    • 0030894060 scopus 로고    scopus 로고
    • Influence of disintegrant type and proportion on the properties of tablets produced from mixtures of pellets
    • Lundqvist Å.E.K., Podczeck F., Newton J.M. Influence of disintegrant type and proportion on the properties of tablets produced from mixtures of pellets. Int. J. Pharm. 147:1997;95-107.
    • (1997) Int. J. Pharm. , vol.147 , pp. 95-107
    • Lundqvist, Å.E.K.1    Podczeck, F.2    Newton, J.M.3
  • 17
    • 0032214494 scopus 로고    scopus 로고
    • Compaction of, and drug release from, coated drug pellets mixed with other pellets
    • Lundqvist Å.E.K., Podczeck F., Newton J.M. Compaction of, and drug release from, coated drug pellets mixed with other pellets. Eur. J. Pharm. Biopharm. 46:1998;369-379.
    • (1998) Eur. J. Pharm. Biopharm. , vol.46 , pp. 369-379
    • Lundqvist, Å.E.K.1    Podczeck, F.2    Newton, J.M.3
  • 18
    • 0027955495 scopus 로고
    • Compaction studies on pellets II. Coated pellets
    • Maganti L., Çelik M. Compaction studies on pellets II. Coated pellets. Int. J. Pharm. 103:1994;55-67.
    • (1994) Int. J. Pharm. , vol.103 , pp. 55-67
    • Maganti, L.1    Çelik, M.2
  • 19
    • 0033955439 scopus 로고    scopus 로고
    • Effect of formulation and process variables on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug
    • Mehta K.A., Kislalioglu M.S., Phuapradit W., Malick A.W., Shah N.H. Effect of formulation and process variables on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug. J. Control. Release. 63:2000;201-211.
    • (2000) J. Control. Release , vol.63 , pp. 201-211
    • Mehta, K.A.1    Kislalioglu, M.S.2    Phuapradit, W.3    Malick, A.W.4    Shah, N.H.5
  • 20
    • 0025294139 scopus 로고
    • The strength of microcrystalline cellulose pellets: The effect of granulating with water/ethanol mixtures
    • Millili G.P., Schwartz J.B. The strength of microcrystalline cellulose pellets: the effect of granulating with water/ethanol mixtures. Drug Dev. Ind. Pharm. 16:1990;1411-1426.
    • (1990) Drug Dev. Ind. Pharm. , vol.16 , pp. 1411-1426
    • Millili, G.P.1    Schwartz, J.B.2
  • 21
    • 0030035742 scopus 로고    scopus 로고
    • Formulation and compaction of nonfracturing deformable coated beads
    • Mount D.L., Schwartz J.B. Formulation and compaction of nonfracturing deformable coated beads. Drug Dev. Ind. Pharm. 22:1996;609-621.
    • (1996) Drug Dev. Ind. Pharm. , vol.22 , pp. 609-621
    • Mount, D.L.1    Schwartz, J.B.2
  • 22
    • 0032824041 scopus 로고    scopus 로고
    • Modulation of the tabletting behaviour of microcrystalline cellulose pellets by the incorporation of polyethylene glycol
    • Nicklasson F., Alderborn G. Modulation of the tabletting behaviour of microcrystalline cellulose pellets by the incorporation of polyethylene glycol. Eur. J. Pharm. Sci. 9:1999;57-65.
    • (1999) Eur. J. Pharm. Sci. , vol.9 , pp. 57-65
    • Nicklasson, F.1    Alderborn, G.2
  • 23
    • 0033805514 scopus 로고    scopus 로고
    • Analysis of the mechanics of pharmaceutical agglomerates of different porosity and composition using the Adams and Kawakita equations
    • Nicklasson F., Alderborn G. Analysis of the mechanics of pharmaceutical agglomerates of different porosity and composition using the Adams and Kawakita equations. Pharm. Res. 17:2000;947-952.
    • (2000) Pharm. Res. , vol.17 , pp. 947-952
    • Nicklasson, F.1    Alderborn, G.2
  • 24
    • 0017112393 scopus 로고
    • Measurement of particle size of free-flowing material with a ring gap sizer
    • Nyström C., Stanley-Wood N. Measurement of particle size of free-flowing material with a ring gap sizer. Acta Pharm. Suec. 13:1976;277-284.
    • (1976) Acta Pharm. Suec. , vol.13 , pp. 277-284
    • Nyström, C.1    Stanley-Wood, N.2
  • 25
    • 0030893960 scopus 로고    scopus 로고
    • Investigations of tablets prepared from pellets produced by extrusion and spheronisation. Part I: The application of canonical analysis to correlate the properties of the tablets to the factors studied in combination with principal component analysis to select the most relevant factors
    • Pinto J.F., Podczeck F., Newton J.M. Investigations of tablets prepared from pellets produced by extrusion and spheronisation. Part I: The application of canonical analysis to correlate the properties of the tablets to the factors studied in combination with principal component analysis to select the most relevant factors. Int. J. Pharm. 147:1997;79-93.
    • (1997) Int. J. Pharm. , vol.147 , pp. 79-93
    • Pinto, J.F.1    Podczeck, F.2    Newton, J.M.3
  • 26
    • 0031033748 scopus 로고    scopus 로고
    • The use of statistical moment analysis to elucidate the mechanism of release of a model drug from pellets produced by extrusion and spheronisation
    • Pinto J.F., Podczeck F., Newton J.M. The use of statistical moment analysis to elucidate the mechanism of release of a model drug from pellets produced by extrusion and spheronisation. Chem. Pharm. Bull. 45:1997;171-180.
    • (1997) Chem. Pharm. Bull. , vol.45 , pp. 171-180
    • Pinto, J.F.1    Podczeck, F.2    Newton, J.M.3
  • 27
    • 0027223963 scopus 로고
    • Comparison of in vitro dissolution profiles by calculating mean dissolution time (MDT) or mean residence time (MRT)
    • Podczeck F. Comparison of in vitro dissolution profiles by calculating mean dissolution time (MDT) or mean residence time (MRT). Int. J. Pharm. 97:1993;93-100.
    • (1993) Int. J. Pharm. , vol.97 , pp. 93-100
    • Podczeck, F.1
  • 28
    • 0003474751 scopus 로고
    • W.H. Press, S.A. Teukolsky, W.T. Vetterling, Flannery B.P. 2nd Edition Cambridge: The Press Syndicate of the University of Cambridge
    • Press W.H., Teukolsky S.A., Vetterling W.T., Flannery B.P. 2nd Edition Numerical Recipes in C. The Art of Scientific Computing. 1992;132 The Press Syndicate of the University of Cambridge, Cambridge.
    • (1992) Numerical Recipes in C. The Art of Scientific Computing , pp. 132
  • 30
    • 0032496612 scopus 로고    scopus 로고
    • Investigations into the deformability and tensile strength of pellets
    • Salako M., Podczeck F., Newton J.M. Investigations into the deformability and tensile strength of pellets. Int. J. Pharm. 168:1998;49-57.
    • (1998) Int. J. Pharm. , vol.168 , pp. 49-57
    • Salako, M.1    Podczeck, F.2    Newton, J.M.3
  • 31
    • 0027930482 scopus 로고
    • In vitro properties of film-coated diltiazem hydrochloride pellets compressed into tablets
    • Sarisuta N., Punpreuk K. In vitro properties of film-coated diltiazem hydrochloride pellets compressed into tablets. J. Control. Release. 31:1994;215-222.
    • (1994) J. Control. Release , vol.31 , pp. 215-222
    • Sarisuta, N.1    Punpreuk, K.2
  • 32
    • 0027993067 scopus 로고
    • Compaction studies on beads: Compression and consolidation parameters
    • Schwartz J.B., Nguyen N.H., Schnaare R.L. Compaction studies on beads: compression and consolidation parameters. Drug Dev. Ind. Pharm. 20:1994;3105-3129.
    • (1994) Drug Dev. Ind. Pharm. , vol.20 , pp. 3105-3129
    • Schwartz, J.B.1    Nguyen, N.H.2    Schnaare, R.L.3
  • 34
    • 0035800227 scopus 로고    scopus 로고
    • Granule deformation and densification during compression of binary mixtures of granules
    • Tunón Å., Alderborn G. Granule deformation and densification during compression of binary mixtures of granules. Int. J. Pharm. 222:2001;65-76.
    • (2001) Int. J. Pharm. , vol.222 , pp. 65-76
    • Tunón, Å.1    Alderborn, G.2
  • 35
    • 0036829173 scopus 로고    scopus 로고
    • Wax beads as cushioning agents during the compression of coated diltiazem pellets
    • Vergote G.J., Kiekens F., Vervaet C., Remon J.P. Wax beads as cushioning agents during the compression of coated diltiazem pellets. Eur. J. Pharm. Sci. 17:2002;145-151.
    • (2002) Eur. J. Pharm. Sci. , vol.17 , pp. 145-151
    • Vergote, G.J.1    Kiekens, F.2    Vervaet, C.3    Remon, J.P.4
  • 36
    • 0033837427 scopus 로고    scopus 로고
    • Pellet-containing tablets. Examination of distribution and deformation behaviour
    • Wagner K.G., Krumme M., Schmidt P.C. Pellet-containing tablets. Examination of distribution and deformation behaviour. S.T.P. Pharma Sci. 10:2000;327-334.
    • (2000) S.T.P. Pharma Sci. , vol.10 , pp. 327-334
    • Wagner, K.G.1    Krumme, M.2    Schmidt, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.