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Volumn 114, Issue 6, 2000, Pages 1188-1194

Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells

Author keywords

Gene therapy; Recombinant adenovirus; Tumor invasiveness; Tumor suppressor genes

Indexed keywords

GELATINASE A; GELATINASE B; MESSENGER RNA; PROTEIN P53;

EID: 0042596102     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00000.x     Document Type: Article
Times cited : (41)

References (58)
  • 2
    • 0028348001 scopus 로고
    • Mutation and expression of the p53 gene in human malignant melanoma
    • Albino AP, Vidai MJ, Mcnutt NS, et al: Mutation and expression of the p53 gene in human malignant melanoma. Melanoma Res 4:35-45, 1994
    • (1994) Melanoma Res , vol.4 , pp. 35-45
    • Albino, A.P.1    Vidai, M.J.2    Mcnutt, N.S.3
  • 3
    • 0031983123 scopus 로고    scopus 로고
    • Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells
    • Bafetti LM, Young TN, Itoh Y, Stack MS: Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells. J Biol Chem 273:142-149, 1998
    • (1998) J Biol Chem , vol.273 , pp. 142-149
    • Bafetti, L.M.1    Young, T.N.2    Itoh, Y.3    Stack, M.S.4
  • 4
    • 0024536654 scopus 로고
    • Chromosome 17 deletions and p53 mutations in colorectal carcinomas
    • Baker SJ, Fearon ER, Nigro JM, et al: Chromosome 17 deletions and p53 mutations in colorectal carcinomas. Science 244:217-221, 1989
    • (1989) Science , vol.244 , pp. 217-221
    • Baker, S.J.1    Fearon, E.R.2    Nigro, J.M.3
  • 5
    • 0030826510 scopus 로고    scopus 로고
    • Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter
    • Bian J, Sun Y: Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter. Mol Cell Biol 17:6330-6338, 1997
    • (1997) Mol Cell Biol , vol.17 , pp. 6330-6338
    • Bian, J.1    Sun, Y.2
  • 6
    • 0030705168 scopus 로고    scopus 로고
    • Loss of finition and p53 protein stabilization
    • Blagoskolonny MV: Loss of finition and p53 protein stabilization. Oncogene 15:1889-1893, 1997
    • (1997) Oncogene , vol.15 , pp. 1889-1893
    • Blagoskolonny, M.V.1
  • 7
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 8
    • 0028851771 scopus 로고
    • Adenovirus-mediated gene transfer of wild-type p53 results in melanoma cell apoptosis in vitro and in vivo
    • Cirielli C, Riccioni T, Yang C, et al: Adenovirus-mediated gene transfer of wild-type p53 results in melanoma cell apoptosis in vitro and in vivo. Int J Cancer 63:1-7, 1995
    • (1995) Int J Cancer , vol.63 , pp. 1-7
    • Cirielli, C.1    Riccioni, T.2    Yang, C.3
  • 10
    • 0031750168 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
    • Clayman GL, El-Naggar AK, Lippman SM, et al: Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J Clin Oncol 16:2221-2232, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 2221-2232
    • Clayman, G.L.1    El-Naggar, A.K.2    Lippman, S.M.3
  • 11
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N: Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265:1582-1584, 1994
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 12
    • 0030954514 scopus 로고    scopus 로고
    • Adjuvant therapy for cutaneous malignant melanoma
    • Demierre MF, Koh HK: Adjuvant therapy for cutaneous malignant melanoma. J Am Acad Dermatol 36:747-764, 1997
    • (1997) J Am Acad Dermatol , vol.36 , pp. 747-764
    • Demierre, M.F.1    Koh, H.K.2
  • 13
    • 0030265337 scopus 로고    scopus 로고
    • The p53-defident mouse: A model for basic and applied cancer studies
    • Donehower LA: The p53-defident mouse: a model for basic and applied cancer studies. Semin Cancer Biol 7:269-278, 1996
    • (1996) Semin Cancer Biol , vol.7 , pp. 269-278
    • Donehower, L.A.1
  • 14
    • 0027818396 scopus 로고
    • A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis
    • Fujiwara T, Grimm EA, Mukhopadhyay T, Cai DW, Owen-Schaub LB, Roth JA: A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis. Cancer Res 53:4129-4133, 1993
    • (1993) Cancer Res , vol.53 , pp. 4129-4133
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Cai, D.W.4    Owen-Schaub, L.B.5    Roth, J.A.6
  • 15
  • 17
    • 0029315806 scopus 로고
    • Methods for construction of adenovirus vectors
    • Graham FL, Prevec L: Methods for construction of adenovirus vectors. Mol Biotechnol 3:207-220, 1995
    • (1995) Mol Biotechnol , vol.3 , pp. 207-220
    • Graham, F.L.1    Prevec, L.2
  • 18
    • 0030462960 scopus 로고    scopus 로고
    • Growth factors and melanomas
    • Halaban R: Growth factors and melanomas. Semin Oncol 23:673-681, 1996
    • (1996) Semin Oncol , vol.23 , pp. 673-681
    • Halaban, R.1
  • 19
    • 0030100291 scopus 로고
    • Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein
    • Harris MP, Sutjipto S, Wills KN, et al: Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Ther 3:121-130, 1995
    • (1995) Cancer Gene Ther , vol.3 , pp. 121-130
    • Harris, M.P.1    Sutjipto, S.2    Wills, K.N.3
  • 20
    • 0029810981 scopus 로고    scopus 로고
    • Overexpression and mutations of p53 in metastatic malignant melanomas
    • Hartmann A, Blaszyk H, Cunningham JS, et al: Overexpression and mutations of p53 in metastatic malignant melanomas. Int J Cancer 67:313-317, 1996
    • (1996) Int J Cancer , vol.67 , pp. 313-317
    • Hartmann, A.1    Blaszyk, H.2    Cunningham, J.S.3
  • 21
    • 0026585963 scopus 로고
    • Coexpression of vimentin and keratins by human melanoma tumor cells: Correlation with invasive and metastatic potential
    • Hendrix MJ, Seftor EA, Chu YW, et al: Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastatic potential. J Natl Cancer Inst 84:165-174, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 165-174
    • Hendrix, M.J.1    Seftor, E.A.2    Chu, Y.W.3
  • 22
    • 0028169906 scopus 로고
    • Modulation of M (r) 72,000 and M (r) 92, 000 type IV collagenase (gelatinase A and B) gene expression by interferons alpha and gamma in human melanoma
    • Hujanen ES, Vaisanen A, Zheng A, Tryggvason K, Turpeenniemi-Hujanen T: Modulation of M (r) 72,000 and M (r) 92, 000 type IV collagenase (gelatinase A and B) gene expression by interferons alpha and gamma in human melanoma. Int J Cancer 58:582-586, 1994
    • (1994) Int J Cancer , vol.58 , pp. 582-586
    • Hujanen, E.S.1    Vaisanen, A.2    Zheng, A.3    Tryggvason, K.4    Turpeenniemi-Hujanen, T.5
  • 23
    • 0026496885 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan MB, Zhan O, El-Deiry WS, et al: Participation of p53 protein in the cellular response to DNA damage. Cell 71:587-597, 1992
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1    Zhan, O.2    El-Deiry, W.S.3
  • 24
    • 0028345645 scopus 로고
    • Quantitative zymography: Detection of picogram quantities of gelatinases
    • Kleiner DE, Stetler-Stevenson GW: Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biohem 218:325-329, 1994
    • (1994) Anal Biohem , vol.218 , pp. 325-329
    • Kleiner, D.E.1    Stetler-Stevenson, G.W.2
  • 26
    • 0027109075 scopus 로고
    • p53, the guardian of the genome
    • Lane DP: p53, the guardian of the genome, Nature (London) 358:15-16, 1992
    • (1992) Nature (London) , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 27
    • 0025173845 scopus 로고
    • P53: Oncogene or antioncogene?
    • Lane DP, Benchimol S: P53: oncogene or antioncogene? Genes Dev 4:1-8, 1990
    • (1990) Genes Dev , vol.4 , pp. 1-8
    • Lane, D.P.1    Benchimol, S.2
  • 28
    • 0029103231 scopus 로고
    • Systemic gene therapy with p53 reduces growth and metastases of a malignant human breast cancer in nude mice
    • Leeson-Wood LA, Kim WH, Kleinman HK, Weintraub BD, Mixson AJ: Systemic gene therapy with p53 reduces growth and metastases of a malignant human breast cancer in nude mice. Hum Gene Ther 6:395-105, 1995
    • (1995) Hum Gene Ther , vol.6 , pp. 395-1105
    • Leeson-Wood, L.A.1    Kim, W.H.2    Kleinman, H.K.3    Weintraub, B.D.4    Mixson, A.J.5
  • 29
    • 0031064517 scopus 로고    scopus 로고
    • The role of Interferon alpha in the treatment of metastatic melanoma
    • Legha SS: The role of Interferon alpha in the treatment of metastatic melanoma. Semin Oncol 24:5424-5431, 1997
    • (1997) Semin Oncol , vol.24 , pp. 5424-5431
    • Legha, S.S.1
  • 30
    • 0029554989 scopus 로고
    • The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a 'gain of function' phenotype
    • Levine AJ, Wu MC, Chang A, Silver A, Attiyeh EF, Lin J, Epstein CB: The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a 'gain of function' phenotype. Ann NY Acad Sci 768:111-128, 1995
    • (1995) Ann NY Acad Sci , vol.768 , pp. 111-128
    • Levine, A.J.1    Wu, M.C.2    Chang, A.3    Silver, A.4    Attiyeh, E.F.5    Lin, J.6    Epstein, C.B.7
  • 32
    • 0030445324 scopus 로고    scopus 로고
    • Expression of the retinoblastoma (RB) tumor suppressor gene inhibits tumor cell invasion in vitro
    • Li J, Hu SX, Perng GS, et al: Expression of the retinoblastoma (RB) tumor suppressor gene inhibits tumor cell invasion in vitro. Oncogene 13:2379-2386, 1996
    • (1996) Oncogene , vol.13 , pp. 2379-2386
    • Li, J.1    Hu, S.X.2    Perng, G.S.3
  • 33
    • 7344252500 scopus 로고    scopus 로고
    • Mutant p53 protein expression interferes with p53-independent apoptotic pathways
    • Li R, Sutphin PD, Schwartz D, et al: Mutant p53 protein expression interferes with p53-independent apoptotic pathways. Oncogene 16:3269-3277, 1998
    • (1998) Oncogene , vol.16 , pp. 3269-3277
    • Li, R.1    Sutphin, P.D.2    Schwartz, D.3
  • 34
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone L, White A, SprouseJ, Livanos E, Jacks T, Tisty TD: Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923-935, 1992
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tisty, T.D.6
  • 36
    • 0030777119 scopus 로고    scopus 로고
    • Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis
    • Luca M, Huang S, Gershenwald JE, Singh RK, Reich R, Bar-Eli M: Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. Am J Pathol 151:1105-1113, 1997
    • (1997) Am J Pathol , vol.151 , pp. 1105-1113
    • Luca, M.1    Huang, S.2    Gershenwald, J.E.3    Singh, R.K.4    Reich, R.5    Bar-Eli, M.6
  • 37
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ: The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245, 1992
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 38
    • 0029740034 scopus 로고    scopus 로고
    • Functional inactivation of p53 by antisense RNA induces invasive ability of lung carcinoma cells and downregulates cytokeratin synthesis
    • Mukhopadhyay T, Roth JA: Functional inactivation of p53 by antisense RNA induces invasive ability of lung carcinoma cells and downregulates cytokeratin synthesis. Anticancer Res 16:1683-1689, 1996
    • (1996) Anticancer Res , vol.16 , pp. 1683-1689
    • Mukhopadhyay, T.1    Roth, J.A.2
  • 39
    • 0030951971 scopus 로고    scopus 로고
    • Strong correlation of basement membrane degradation with p53 inactivation and/or mdm2 overexpression in superficial urothelial carcinomas
    • Ozdemir E, Kakehi Y, Okuno H, Habuchi T, Okada Y, Yoshida O: Strong correlation of basement membrane degradation with p53 inactivation and/or mdm2 overexpression in superficial urothelial carcinomas. J Urol 158:206-211, 1997
    • (1997) J Urol , vol.158 , pp. 206-211
    • Ozdemir, E.1    Kakehi, Y.2    Okuno, H.3    Habuchi, T.4    Okada, Y.5    Yoshida, O.6
  • 40
    • 0027447696 scopus 로고
    • Tumor-suppressor p53 and the cell cycle
    • Perry ME, Levine AJ: Tumor-suppressor p53 and the cell cycle. Curr Opin Genet Dev 3:50-54, 1993
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 50-54
    • Perry, M.E.1    Levine, A.J.2
  • 41
    • 0028073883 scopus 로고
    • The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis
    • Ray JM, Stetler-Stevenson WG: The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur Respir J 7:2062-2072, 1994
    • (1994) Eur Respir J , vol.7 , pp. 2062-2072
    • Ray, J.M.1    Stetler-Stevenson, W.G.2
  • 42
    • 0028948844 scopus 로고
    • Gelatinase A activity directly modulates melanoma cell adhesion and spreading
    • Ray JM, Stetler-Stevenson WG: Gelatinase A activity directly modulates melanoma cell adhesion and spreading. EMBO J 14:908-917, 1995
    • (1995) EMBO J , vol.14 , pp. 908-917
    • Ray, J.M.1    Stetler-Stevenson, W.G.2
  • 43
    • 0031857875 scopus 로고    scopus 로고
    • Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo
    • Riccioni T, Cirielli C, Wang X, Passaniti A, Capogrossi MC: Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo. Gene Ther 5:747-754, 1998
    • (1998) Gene Ther , vol.5 , pp. 747-754
    • Riccioni, T.1    Cirielli, C.2    Wang, X.3    Passaniti, A.4    Capogrossi, M.C.5
  • 44
    • 0029984475 scopus 로고    scopus 로고
    • The incidence of malignant melanoma in the United States: Issues as we approach the 21st century
    • Rigel DS, Friedman RJ, Kopf AW: The incidence of malignant melanoma in the United States: issues as we approach the 21st century. J Am Acad Dermatol 34:839-847, 1996
    • (1996) J Am Acad Dermatol , vol.34 , pp. 839-847
    • Rigel, D.S.1    Friedman, R.J.2    Kopf, A.W.3
  • 45
    • 9544244796 scopus 로고    scopus 로고
    • Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
    • Roth JA, Nguyen D, Lawrence DD, et al: Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Med 2:985-981, 1996
    • (1996) Nature Med , vol.2 , pp. 985-1981
    • Roth, J.A.1    Nguyen, D.2    Lawrence, D.D.3
  • 46
    • 0031828108 scopus 로고    scopus 로고
    • Gene therapy for non-small cell lung cancer: A preliminary report of a phase I trial of adenoviral p53 gene replacement
    • Roth JA, Swisher SG, Merrit JA, et al: Gene therapy for non-small cell lung cancer: a preliminary report of a phase I trial of adenoviral p53 gene replacement. Semin Oncol 25 (3, Suppl. 8):33-37, 1998
    • (1998) Semin Oncol , vol.25 , Issue.3 SUPPL. 8 , pp. 33-37
    • Roth, J.A.1    Swisher, S.G.2    Merrit, J.A.3
  • 47
    • 17344365479 scopus 로고    scopus 로고
    • A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer
    • Schuler M, Rochlitz C, Horowitz JA, et al: A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer. Hum Gene Ther 9:2075-2082, 1998
    • (1998) Hum Gene Ther , vol.9 , pp. 2075-2082
    • Schuler, M.1    Rochlitz, C.2    Horowitz, J.A.3
  • 48
    • 0033526357 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer in advanced non-small-cell lung cancer
    • Swisher SG, Roth JA, Nemunaitis J, et al: Adenovirus-mediated gene transfer in advanced non-small-cell lung cancer. J Natl Cancer Inst 91:763-771, 1999
    • (1999) J Natl Cancer Inst , vol.91 , pp. 763-771
    • Swisher, S.G.1    Roth, J.A.2    Nemunaitis, J.3
  • 49
    • 0028606364 scopus 로고
    • Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and heparocellular carcinoma cells
    • Ueba T, Nosaka T, Takahashi JA, et al: Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and heparocellular carcinoma cells. Pror Natl Acad Sci USA 91:9009-9013, 1994
    • (1994) Pror Natl Acad Sci USA , vol.91 , pp. 9009-9013
    • Ueba, T.1    Nosaka, T.2    Takahashi, J.A.3
  • 50
    • 0029831503 scopus 로고    scopus 로고
    • Matrix-metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumor progression and may have prognostic value
    • Väisänen A, Tuominen H, Kallioinen M, Turpeenniemi-Hujanen T: Matrix-metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumor progression and may have prognostic value. J Pathol 180:283-289, 1996
    • (1996) J Pathol , vol.180 , pp. 283-289
    • Väisänen, A.1    Tuominen, H.2    Kallioinen, M.3    Turpeenniemi-Hujanen, T.4
  • 53
    • 0031014797 scopus 로고    scopus 로고
    • Inhibition of DNA topoisomerase IIa gene expression by the p53 tumor suppressor
    • Wang Q, Zambetti GP, Suttle DP: Inhibition of DNA topoisomerase IIa gene expression by the p53 tumor suppressor. Mol Cell Biol 17:389-397, 1997
    • (1997) Mol Cell Biol , vol.17 , pp. 389-397
    • Wang, Q.1    Zambetti, G.P.2    Suttle, D.P.3
  • 55
    • 0029027072 scopus 로고
    • Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of prostatic tumor cells
    • Yang C, Cirielli C, Capogrossi MC, Passaniti A: Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of prostatic tumor cells. Cancer Res 55:4210-4213, 1995
    • (1995) Cancer Res , vol.55 , pp. 4210-4213
    • Yang, C.1    Cirielli, C.2    Capogrossi, M.C.3    Passaniti, A.4
  • 56
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin Y, Tainsky MA, Bischoff ZF, Strong IC, Wahl GM: Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948, 1992
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, Z.F.3    Strong, I.C.4    Wahl, G.M.5
  • 57
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M: Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352:345-347, 1991
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


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