Best practice No 172: Pituitary gland pathology

Journal of Clinical Pathology

Volumn 56, Issue 8, 2003, Pages 561-568

  Ironside, J W ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER INVASION; CARCINOMA; CELL ULTRASTRUCTURE; CYTOGENETICS; DIAGNOSTIC PROCEDURE; DISEASE CLASSIFICATION; GENETIC SUSCEPTIBILITY; HISTOPATHOLOGY; HUMAN; HYPERPLASIA; HYPOPHYSIS ADENOMA; HYPOPHYSIS TUMOR; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SYMPTOMATOLOGY; TUMOR BIOPSY;

ADENOMA; CARCINOMA; CYTOGENETIC ANALYSIS; HISTOCYTOCHEMISTRY; HUMANS; HYPERPLASIA; INTRAOPERATIVE PERIOD; MITOTIC INDEX; PITUITARY GLAND; PITUITARY NEOPLASMS; SPECIMEN HANDLING; TUMOR MARKERS, BIOLOGICAL;

EID: 0042591442     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.56.8.561     Document Type: Review

References (106)

1. Asa SL. Tumors of the pituitary gland. Atlas of tumor pathology. 3rd series, Fascicle 22. Washington: Armed Forces Institute of Pathology, 1998.
2. Kaye AH, Laws ER, eds. Brain tumors. An encyclopedic approach. Edinburgh: Churchill Livingstone, 1995.
3. Thapar K, Kovacs K. Neoplasms of the sellar region. In: Bigner DD, McLendon R, Bruner J, eds. Russell and Rubinstein's pathology of tumors of the nervous system, 6th ed. London: Arnold, 1998.
4. Horvath E, Scheithauer BW, Kovacs K, et al. Hypothalamus and pituitary. In Graham DI, Lantos PL, eds. Greenfield's neuropathology, 7th ed. London: Arnold, 2002.
5. Ironside JW, Moss TH, Louis DN, et al. Diagnostic pathology of nervous system tumours. Edinburgh: Churchill Livingstone, 2002.
6. Freda PU, Post KD. Differential diagnosis of sellar masses. Clin Endocrinol Metab North Am 1999;28:81-117.
7. Connor SEJ, Penny CC. MRI in the differential diagnosis of a sellar mass. Clin Radiol 2003;58:20-31.
8. Naidich MJ, Russell EJ. Current approaches to imaging of the sellar region and pituitary. Endocrinol Metab Clin North Am 1999;28:45-80.
9. Laws ER, Jr, Thapar K. Pituitary surgery. Clin Endocrinol Metab North Am 1999;28:119-32.
10. Zhang X, Fei Z, Zhang J, et al. Management of non-functioning pituitary adenomas with suprasellar extensions by transsphenoidal microsurgery. Surg Neurol 1999;52:380-5.
11. Hae-Dong J. Endoscopic transsphenoidal surgery. J Neurooncol 2001;54:187-95.
12. McLendon RE, Bigner DD, Bigner SH, et al. Pathology of tumors of the central nervous system. A guide to histotogic diagnosis. London: Arnold, 2000.
13. Moss TH, Nicoll JAR, Ironside JW. Intra-operative diagnosis of CNS tumours. London: Arnold, 1997.
14. Smith AR, Elsheikh TM, Silverman JF. Intraoperative cytologic diagnosis of suprasellar and sellar cystic lesions. Diagn Cytopathol 1999;20:137-47.
15. Ng HK. Smears in the diagnosis of pituitary adenomas. Acta Cytol 1998;42:614-18.
16. Adelman LS, Post KD. Intra-operative frozen section diagnosis for pituitary adenomas. Am J Surg Pathol 1979;3:173-5.
17. Velasco ME, Sindely SO, Roessmann U. Reticulum stain for frozen-section diagnosis of pituitary adenomas. Technical note. J Neurosurg 1977;46:548-50.
18. Kovacs K, Horvath E, Vidal S. Classification of pituitary adenomas. J Neurooncol 2001;54:121-7.
19. Kujas M. Pituitary adenomas. Ann Pathol 2001;21:237-43.
20. Kunwar S, Charles B, Wilson B. Pediatric pituitary adenomas. J Clin Endocrinol Metab 1999;84:4385-9.
21. Lakka-Papadodima E. Non-secreting pituitary tumors in adolescents - consequence in adulthood. J Pediatr Endocrinol Metab 2001;14:1217-26.
22. Turner HE, Adams CB, Wass JA. Pituitary tumours in the elderly: a 20 year experience. Eur J Endocrinol 1999;140:383-9.
23. Arafah BM, Nasrallah MP. Pituitary tumors: pathophysiology, clinical manifestations and management. Endocr Relat Cancer 2001;8:287-305.
24. Tomita T, Gates E. Pituitary adenomas and granular cell tumors. Incidence, cell type and location of tumor in 100 pituitary glands at autopsy. Am J Clin Pathol 1999;111:817-25.
25. Hosaka N, Kitajiri S, Hiraumi H, et al. Ectopic pituitary adenoma with malignant transformation. Am J Surg Pathol 2002;26:1078-82.
26. Axiotis CA, Lippes HA, Merino MJ, et al. Corticotroph cell pituitary adenoma within an ovarian teratoma. A new cause of Cushing's syndrome. Am J Surg Pathol 1987;11:218-24.
27. McKelvie PA, McNeill P. Double pituitary adenomas: a series of three patients. Pathology 2002;34:57-60.
28. Meij BP, Lopes MB, Vance ML, et al. Double pituitary lesions in three patients with Cushing's disease. Pituitary 2000;3:159-68.
29. Robin MR, Bruce JN, Khandji AG, et al. Sarcoidosis within a pituitary adenoma. Pituitary 2001;4:195-202
30. Zhang X, Li Q, Hu P, et al. Two case reports of pituitary adenoma associated with Toxoplasma gondii infection. J Clin Pathol 2002;55:965-6.
31. Hanna FW, Williams OM, Davies JS, et al. Pituitary apoplexy following metastasis of bronchogenic adenocarcinoma to a prolactinoma. Clin Endocrinol 1999;51:377-81.
32. Hardy J. Transphenoidal microsurgery of the normal and pathological pituitary. Clin Neurosurg 1969;16:185-217.
33. Oruckaptan HH, Senmevsim O, Ozcan OK, et al. Pituitary adenomas: results of 684 surgically treated patients and review of the literature. Surg Neurol 2000;53:211-19.
34. Blevins LS, Jr, Verity DK, Allen G. Aggressive pituitary tumors. Oncology (Huntingt) 1998;12:1307-12, 1315-18.
35. Meij BP, Lopes MB, Ellegala DB, et al. The long-term significance of microscopic dural invasion in 354 patients with pituitary adenomas treated with transsphenoidal surgery. J Neurosurg 2002;96:195-208.
36. Asa SL, Kovacs K, Horvath E, et al. Hormone secretion in vitro by plurihormonal pituitary adenomas of acidophil stem cell line. J Clin Endocrinol Metab 1992;75:68-75.
37. Giangaspero F, Cenacchi G. Oncocytic and granular cell neoplasms of the central nervous system and pituitary gland. Semin Diagn Pathol 1999;16:91-7.
38. Horvarth E, Kovacs K, Smyth HS, et al. A novel type of pituitary adenoma: morphological features and clinical correlations. J Clin Endocrinol Metab 1988;66:1111-18.
39. Selman WR, Laws ER, Jr, Scheithauer BW, et al. The occurrence of dural invasion in pituitary adenomas. J Neurosurg 1986;64:402-7
40. Bradley KJ, Wass JAH, Turner HE. Non-functioning pituitary adenomas with positive immunoreactivity For ACTH behave more aggressively than ACTH immunonegative tumours but do not recur more frequently. Clin Endocrinol 2003;58:59-64.
41. Scheithauer BW, Jaap AJ, Horvath E, et al. Clinically silent corticotroph tumors of the pituitary gland. Neurosurgery 2000;47:723-9.
42. Gaffey TA, Scheithauer BW, Lloyd RV, et al. Corticotroph carcinoma of the pituitary: a clinicopathologic study. J Neurosurg 2002;96:352-60.
43. Thapar K, Yamada Y, Scheithauer BW, et al. Assessment of mitotic activity in pituitary adenomas and carcinomas. Endocr Pathol 1996;7:215-21.
44. Anniko M, Tribukait B, Wersall J. Significance of high percentages of S-phase cells in human pituitary tumours. ORL J Otorhinolaryngol Relat Spec 1983;45:177-86.
45. Chatterjee S, May PL, Forster G, et al. Prediction of recurrence in pituitary tumours: a flow cytometric study using in vivo bromodeoxyuridine. Br J Neurosurg 1993;7:165-9.
46. Thapar K, Kovacs K, Scheithauer BW, et al. Proliferative activity and invasiveness among pituitary adenomas and carcinomas: an analysis using the MIB-1 antibody. Neurosurgery 1996;38:99-106
47. Turner HE, Wass JA. Are markers of proliferation valuable in the histological assessment of pituitary tumours? Pituitary 1999;1:147-51.
48. Hucumenoglu S, Kaya H, Kotiloglu E, et al. AgNOR values are not helpful in the differential diagnosis of pituitary adenomas. Clin Neurol Neurosurg 2002;104:293-9.
49. Oliveira MC, Marroni CP, Pizarro CB, et al. Expression of p53 protein in pituitary adenomas. Braz J Med Biol Res 2002;35:561-5.
50. Kumar K, Macaulay RJ, Kelly M, et al. Absent p53 immunohistochemical staining in a pituitary carcinoma. Can J Neurol Sci 2001;28:174-8.
51. Gandour-Edwards R, Kapadia SB, Janecka IP, et al. Biologic markers of invasive pituitary adenomas involving the sphenoid sinus. Mod Pathol 1995;8:160-4.
52. Shimon I, Hinton DR, Weiss MH, et al. Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness. Clin Endocrinol (Oxf) 1998;48:23-9.
53. Pichard C, Gerber S, Laloi M, et al. Pituitary carcinoma: report of an exceptional case and review of the literature. J Endocrinol Invest 2002;25:65-72.
54. Popadic A, Witzmann A, Buchfelder M, et al. Malignant prolactinoma: case report and review of the literature. Surg Neurol 1999;51:47-54.
55. Horvath E, Kovacs K, Scheithauer BW. Pituitary hyperplasia. Pituitary 1999;1:169-79.
56. Suhardja AS, Kovacs KT, Rutka JT. Molecular pathogenesis of pituitary adenomas: a review. Acta Neurochir (Wien) 1999;141:729-36.
57. Clayton RN, Farrell WE. Clonality of pituitary tumours: more complicated than initially envisaged? Brain Pathol 2001;11:313-27.
58. Vidal S, Horvath E, Syro LV, et al. Prolactin-producing pituitary adenoma associated with prolactin cell hyperplasia. Endocrinol Pathol 2002;13:157-65.
59. Asa SL, Ezzat S. The pathogenesis of pituitary tumours. Nat Rev Cancer 2002;2:836-49.
60. Faglia G, Spada A. Genesis of pituitary adenomas: state of the art. J Neurooncol 2001;54:95-110.
61. Buch H, El-Hadd T, Bicknell J, et at. Pituitary tumours are multiclonal from the outset: evidence from a case with dural metastases. Clin Endocrinol (Oxf) 2002;56:817-22.
62. Boggild MD, Jenkinson S, Pistorello M, et al. Molecular genetic studies of sporadic pituitary tumors. J Clin Endocrinol Metab 1994;78:387-93.
63. Farrell WE, Clayton RN. Molecular pathogenesis of pituitary tumors. Front Neuroendocrinol 2000;21:174-98.
64. Lloyd RV. Molecular pathology of pituitary adenomas. J Neurooncol 2001;54:111-19.
65. Komminoth P, Heitz PU, Kloppel G. Pathology of MEN-1: morphology, clinicopathologic correlations and tumour development. J Int Med 1998;243:455-64.
66. Sandrini F, Kirschner LS, Bei T, et al. PRKAR1A, one of the Carney complex genes, and its Iocus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex. J Med Genet 2002;39:e78.
67. Alexander JM. Tumor suppressor loss in pituitary tumors. Brain Pathol 2001;11:342-55.
68. Yu R, Melmed S. Oncogene activation in pituitary tumors. Brain Pathol 2001;11:328-41.
69. Karga HJ, Alexander JM, Hedley-Whyte ET, et al. Ras mutations in human pituitary tumors. J Clin Endocrinol Metab 1992;74:914-19.
70. Pei L, Melmed S, Scheithauer B, et al. H-ras mutations in human pituitary carcinoma metastases. J Clin Endocrinol Metab 1994;78:842-6.
71. Nam D-H, Song S-Y, Park K, et al. Clinical significance of molecular genetic changes in invasive pituitary adenomas. Exp Mol Med 2001;33:111-16.
72. Suhardja A, Kovacs K, Rutka J. Genetic basis of pituitary adenoma invasiveness: a review. J Neurooncol 2001;52:195-204.
73. Spada A, Vallar L. G-protein oncogenes in acromegaly. Horm Res 1992;38:90-3.
74. Ruebel KH, Jin L, Zhang S, et al. Inactivation of the p16 gene in human pituitary non-functioning tumors by hypermethylation is more common in null cell adenomas. Endocr Pathol 2001;12:281-9.
75. Seeman N, Kuhn D, Wrocklage C, et al. CDKN2A/p16 inactivation is related to pituitary adenoma type and size. J Pathol 2001;193:491-7.
76. Zhang X, Horwitz GA, Heaney AP, et al. Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas. J Clin Endocrinol Metab 1999;84:761-7.
77. Hunter JA, Skelly RH, Aylwin SJ, et al. The relationship between pituitary tumour transforming gene (PTTG) expression and in vitro hormone and vascular endothelial growth factor (VEGF) secretion from human pituitary adenomas. Eur J Endocrinol 2003;148:203-11.
78. Simpson DJ, Fryer AA, Grossman AB, et al. Cyclin D1 (CCND1) genotype is associated with tumour grade in sporadic pituitary adenomas. Carcinogenesis 2001;22:1801-7.
79. Ezzat S, Zheng L, Zhu X-F, et al. Targeted expression of a human pituitary-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest 2002;109:69-78.
80. Inoue T, Matushima T, Fukui M, et al. Immunohistochemical study of intracranial cysts. Neurosurgery 1988;23:576-81.
81. Kleihues P, Cavenee WK, eds. Tumours of the nervous system. Pathology and genetics. World Health Organisation classification of tumours. Lyon: IARC, 2000.
82. Kovacs K, Horvath E. The differential diagnosis of lesions involving the sella turcica. Endocr Pathol 2001;12:389-95.
83. Lloyd RV, Scheihauer BW, Kovacs K, et al. The immunophenotype of pituitary adenomas. Endocr Pathol 1996;7:145-50.
84. Losa M, Saeger W, Mortini P, et al. Acromegaly associated with a granular cell tumor of the neurohypophysis: a clinical and histological study. Case report. J Neurosurg 2000;93:121-6.
85. Brat DJ, Scheithauer BW, Staugaitis SM, et at. Pituicytoma: a distinctive low-grade glioma of the neurohypophysis. Am J Surg Pathol 2000;24:362-8.
86. Figarella-Branger D, Dufour H, Fernandez C, et al. Pituicytomas, a mis-diagnosed benign tumor of the neurohypophysis: report of 3 cases. Acta Neuropathol 2002;104:313-19.
87. Schultz AB, Brat DJ, Oyesiku NM, et al. Intrasellar pituicytoma in a patient with other endocrine neoplasms. Arch Pathol Lab Med 2001;125:527-30.
88. Geddes J, Jannsen GH, Robinson SF, et al. "Gangliocytomas" of the pituitary: a heterogenous group of lesions with differing histogenesis. Am J Surg Pathol 2000;24:607-13.
89. McCowen KC, Glickman JN, Black PM, et al. Gangliocytoma masquerading as a prolactinoma. Case report. J Neurosurg 1999;91:490-5.
90. Fehn M, Lohmann F, Ludecke DK, et al. Ganglioglioma of the neurohypophysis with secretion of vasopressin. Exp Clin Endocrinol Diabetes 1998;106:425-30.
91. Horvath E, Kovacs K, Tran A, et al. Ganglion cel s in the posterior pituitary: result of ectopia or transdifferentiation? Acta Neuropathol 2000;100:106-10.
92. Giustina A, Gola M, Doga M, et al. Clinical review 136. Primary lymphoma of the pituitary: an emerging clinical entity. J Clin Endocrinol Metab 2001;86:4567-75.
93. Tacconi L, Farah JO, Rossi ML, et al. Neurohypophyseal pilocytic astrocytoma invading the skull base. Br J Neurosurg 1999;13:614-17.
94. Arita K, Kurisu K, Tominaga A, et al. Intrasellar pleomorphic xanthoastrocytoma: case report. Neurosurgery 2002;51:1079-82.
95. Thomson S, Chakrabarty A, Marks P. Ependymcma of the neurohypophysis. Br J Neurosurg 2001;15:277-8.
96. Roncaroli F, Scheithauer BW, Cenacchi G, et al. "Spindle cell oncocytoma" of the adenohypophysis: a tumor of folliculostellate cells? Am J Surg Pathol 2002;26:1048-55.
97. Fuller CE, Frankel B, Smith M, et al. Suprasellar monomorphous pilomyxoid neoplasm: an ultrastructural analysis. Clin Neuropathol 2001;20:256-62.
98. Shin JL, Asa SL, Woodhouse U, et al. Cystic lesions of the pituitary: clinicopathological features distinguishing craniopharyngioma, Rathke's cleft cyst and arachnoid cyst. J Clin Endocrinol Metab 1999;84:3972-82.
99. Vates GE, Berger MS, Wilson CB. Diagnosis and management of pituitary abscess: a review of twenty-four cases. J Neurosurg 2001;95:233-41.
100. Skandarajah A, Hoe W, Gonzales M, et al. Lymphocytic hypophysitis mimicking pituitary macroadenoma. J Clin Neurosci 2002;9:586-9.
101. Ouma JR, Farrell VJR. Lymphocytic infundibulo-neurohypophysitis with hypothalamic and optic pathway involvement: report of a case and review of the literature. Surg Neurol 2002;57:49-53.
102. Sharma MC, Arora R, Mahapatra AK, et al. Intrasellar tuberculoma - an enigmatic pituitary infection: a series of 18 cases. Clin Neurol Neurosurg 2000;10:72-7.
103. Oweity T, Scheithauer BW, Ching HS, et al. Multiple system Erdheim-Chester disease with massive hypothalamic-sellar involvement and hypopituitarism. J Neurosurg 2002;96:344-51.
104. Mosca L, Costanzi G, Antonacci C, et al. Hypoohyseal pathology in AIDS. Histol Histopathol 1992;7:291-300.
105. Murialdo G, Tamagno G. Endocrine aspects of neurosarcoidosis. J Endocrinol Invest 2002;25:650-62.
106. Murakami K, Muraishi K, Ikeda H, et al. Plasma cell granuloma of the pituitary gland. Surg Neurol 2001;56:247-51.