Pituitary tumours are multiclonal from the outset: Evidence from a case with dural metastases

Clinical Endocrinology

Volumn 56, Issue 6, 2002, Pages 817-822

  Buch, H ^a   El Hadd, T ^a   Bicknell, J ^a   Simpson, D J ^a   Farrell, W E ^a   Clayton, R N ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELISM; ARTICLE; AUTOPSY; BRAIN HEMORRHAGE; CASE REPORT; FOLLOW UP; FORAMEN MAGNUM; GENETIC ANALYSIS; HETEROZYGOSITY; HISTOLOGY; HUMAN; HYPOPHYSIS ADENOMA; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; INFUNDIBULUM; LAMINECTOMY; MALE; METASTASIS; MOLECULAR CLONING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADENOMA; BRAIN NEOPLASMS; FATAL OUTCOME; GENE DELETION; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; NEOPLASM SEEDING; NEOPLASM, RESIDUAL; PITUITARY NEOPLASMS;

EID: 0036069072     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2002.01524.x     Document Type: Article

References (9)

1. Clinically non-functional pituitary tumours are monoclonal in origin
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3. Molecular genetic studies of sporadic pituitary tumours
4. Tumour suppressor genes in the pathogenesis of human pituitary tumours
5. Clonality of pituitary tumours: More complicated than initially envisaged
6. Different patterns of allelic loss in recurrent human pituitary tumours provide evidence for multiclonal origins
7. Clonal origin of pituitary adenomas
8. Association of somatotrophinomas with loss of alleles on chromosome 11 with gsp mutations
9. Distinct clonal composition of primary and metastatic adrenocorticotropic hormone producing pituitary carcinoma