Mechanism of Rhodopsin Activation as Examined with Ring-constrained Retinal Analogs and the Crystal Structure of the Ground State Protein

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26148-26153

  Jang, Geeng Fu ^a   Kuksa, Vladimir ^a   Filipek, Stawomir ^c   Bartl, Franz ^d   Ritter, Eglof ^d   Gelb, Michael H ^a,b   Hofmann, Klaus Peter ^d   Palczewski, Krzysztof ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WARSAW   (Poland)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOLOGICAL MEMBRANES; CHEMICAL ACTIVATION; CHROMOPHORES; CONFORMATIONS; CRYSTAL STRUCTURE; ISOMERIZATION; PROTEINS;

CONFORMATIONAL CHANGES;

BIOCHEMISTRY;

11 CIS RETINAL; BETA IONONE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; OPSIN; RETINAL; RHODOPSIN;

ARTICLE; BINDING SITE; CHROMATOPHORE; CIS TRANS ISOMERISM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GEOMETRY; ISOMER; NIGHT VISION; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; CATTLE; CHEMISTRY; METABOLISM; RETINA; STRUCTURE ACTIVITY RELATION;

ANIMALS; CATTLE; PROTEIN CONFORMATION; RETINA; RHODOPSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035854788     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102212200     Document Type: Article

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