Epiregulin is more potent than EGF or TGFα in promoting in vitro wound closure due to enhanced ERK/MAPK activation

Journal of Cellular Biochemistry

Volumn 89, Issue 6, 2003, Pages 1126-1137

  Draper, Bradley K ^a,c   Komurasaki, Toshi ^b   Davidson, Mari K ^a   Nanney, Lillian B ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cell proliferation; Migration; Phosphorylation; Signal transduction; Wound healing

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIREGULIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOMYCIN C; PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPIDERMIS CELL; EXCISION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WOUND CLOSURE; WOUND HEALING;

CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FLAVONOIDS; HUMANS; IMMUNOBLOTTING; KERATINOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; MITOMYCIN; NUCLEIC ACID SYNTHESIS INHIBITORS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR ALPHA; WOUND HEALING;

MURINAE;

EID: 0042570776     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10584     Document Type: Article

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