Enhanced modulation of keratinocyte motility by transforming growth factor-α (TGF-α) relative to epidermal growth factor (EGF)

Journal of Investigative Dermatology

Volumn 106, Issue 4, 1996, Pages 590-597

  Cha, Donald ^a   O'Brien, Patricia ^a   O'Toole, Edel A ^a   Woodley, David T ^a   Hudson, Laurie G ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

EGF receptor; Locomotion; Squamous cell carcinoma

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; RECOMBINANT EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; KERATINOCYTE; MITOGENESIS; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; WOUND HEALING;

EID: 0029875130     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12345083     Document Type: Article

References (44)

1. Ando Y, Jensen PJ: Epidermal growth factor and insulin-like growth factor I enhance keratinocyte migration. J Invest Dermatol 100:633-639, 1993
2. Barrandon Y, Green H: Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-α and epidermal growth factor. Cell 50:1131-1137, 1987
3. Bennett NT, Schultz GS: Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg 165:728-737, 1993a
4. Bennett NT, Schultz GS: Growth factors and wound healing: part II. Role in normal and chronic wound healing. Am J Surg 166:74-81, 1993b
5. Boyce ST, Ham RG: Calcium regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum free serial culture. J Invest Dermatol 81:33s-40s, 1983
6. Brown GL, Nanney LB, Griffin J, et al: Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med 321:76-79, 1989
7. Cadena DL, Gill GN: Receptor tyrosine kinases. FASEB J 6:2232-2337, 1993
8. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S: Oncogenes and signal transduction. Cell 64:281-302, 1991
9. Chen P, Gupta K, Wells A: Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis. J Cell Biol 124:547-555, 1994
10. Chen JD, Kim JP, Zhang K, Sarret Y, Wynn KC, Kramer RH, Woodley DT: Epidermal growth factor (EGF) promotes human keratinocyte locomotion on collagen by increasing the alpha 2 integrin subunit. Exp Cell Res 209:216-223, 1993
11. Chen WS, Lazar CS, Poenie M, Tsien R, Gill GN, Rosenfeld MG: Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature 328:820-823, 1987
12. Derynck R: The physiology of transforming growth factor-alpha. Adv Cancer Res 58:27-52, 1992
13. Ebner R, Derynck R: Epidermal growth factor and transforming growth factor-alpha: differential intracellular routing and processing of ligand-receptor complexes. Cell Regul 2:599-612, 1991
14. French AR, Tadaki DK, Niyogi SK, Lauffenburger DA: Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction. J Biol Chem 270:4334-4340, 1995
15. Gehm BD, Rosner MR: Regulation of insulin, epidermal growth factor and transforming growth factor-alpha levels by growth factor degrading enzymes. Endocrinology 128:1603-1610, 1991
16. Hartmann G, Naldini L, Weidner KM, Sachs M, Vigna E, Comoglio PM, Birchmeier W: A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-MET receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci USA 89:11574-11578, 1992
17. Hashimoto K, Higashiyama S, Asada H, Hashimura E, Kobayashi T, Sudo K, Nakagawa T, Damm D, Yoshikawa K, Taniguchi N: Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J Biol Chem 269:20060-20066, 1994
18. Hennessey PJ, Black CT, Andrassy RJ: EGF increases short-term type 1 collagen accumulation during wound healing in diabetic rats. J Pediatr Surg 25:893-897, 1990
19. Hommel U, Harvey TS, Driscoll PC, Campbell ID: Human epidermal growth factor: high resolution solution structure and comparison with human transforming growth factor alpha. J Mol Biol 227:271-282, 1992
20. Hudson LG, Gill GN: Regulation of gene expression by epidermal growth factor. In: Genetic Engineering, Principles and Methods. Vol. 13. Plenum Press, New York, 1991, pp 137-152
21. Hudson LG, Toscano WA Jr, Greenlee WF: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) modulates epidermal growth factor binding to basal cells from a human keratinocyte cell line. Toxicol Appl Pharmacol 82:481-492, 1986
22. Ju WD, Schiller JT, Kazempour MK, Lowry DR: TGFα enhances locomotion of cultured human keratinocytes. J Invest Dermatol 100:628-632, 1993
23. Kirsner RS, Eaglstein WH: The wound healing process. Dermatol Clin 11:629-640, 1993
24. Matthay MA, Thiery JP, Lafont F, Stampfer MF, Boyer B: Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. J Cell Sci 106:869-878, 1993
25. Mauviel A: Cytokine regulation of metalloproteinase gene expression. J Cell Biochem 53:288-295, 1993
26. McKay IA, Leigh IM: Epidermal cytokines and their roles in cutaneous wound healing. Br J Dermatol 124:513-518, 1991
27. Moriai T, Kobrin MS, Hope C, Speck L, Korc M: A variant epidermal growth factor receptor exhibits altered type α transforming growth factor binding and transmembrane signaling. Proc Natl Acad Sci USA 91:10217-10221, 1994
28. Moriai T, Kobrin MS, Korc M: Cloning of a variant epidermal growth factor receptor. Biohem Biophys Res Commun 191:1034-1039, 1993
29. Nanney LB: Epidermal and dermal effects of epidermal growth factor during wound repair. J Invest Dermatol 94:624-629, 1990
30. Nanney LB, Magid M, Stoscheck CM, King LE Jr: Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol 83:385-393, 1984
31. Nelson WJ, Veshnock HJ: Dynamics of membrane-skeleton (fodrin) organization during development of polarity in Madin-Darby canine kidney epithelial cells. J Cell Biol 103:1751-1765, 1986
32. Peterson GL: A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 83:346-356, 1977
33. Pittelkow MR, Cook PW, Shipley GD, Derynck R, Coffey RJ Jr: Autonomous growth of human keratinocytes requires epidermal growth factor receptor occupancy. Cell Growth Differentiation 4:513-521, 1993
34. Sarret Y, Woodley DT, Grigsby K, Wynn KC, O'Keefe EJ: Human kerarinocyte locomotion: the effect of selected cytokines. J Invest Dermatol 98:12-16, 1992
35. Schultz G, Rotatori DS, Clark W: EGF and TGF-α in wound healing and repair. J Cell Biol 45:346-352, 1991
36. Schultz GS, White M, Mitchell R, Brown G, Lynch J, Twardzik DR, Tadaro GJ: Epithelial wound healing enhanced by transforming growth factor alpha and vaccinia growth factor. Science 235:350-352, 1987
37. Stoscheck CM, Nanney LB, King LE: Quantitative determination of EGF-R during epidermal wound healing. J Invest Dermatol 99:645-649, 1992
38. Takeichi K: Cadherins in cancer: implications for invasion and metastasis. Curr Opin Cell Biol 5:806-811, 1993
39. Thiery JP, Boyer B: The junction hetween cytokines and cell adhesion. Curr Opin Cell Biol 4:782-792, 1992
40. Tucker GC, Boyer B, Valles AM, Thiery JP: Combined effects of extracellular matrix and growth factors on NBT-II rat bladder carcinoma cell dispersion. J Cell Sci 100:371-380, 1991
41. Vallés AM, Tucker GC, Thiery JP, Boyer B: Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line. Cell Regul 1:975-988, 1990
42. Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W: Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 111:2097-2108, 1990
43. Woodley DT, Bachmann PM, O'Keefe E: Laminin inhibits human keratinocyte migration. J Cell Physiol 136:140-146, 1988
44. Yarnaguchi M, Ogren L, Kurachi H, Hirota K, Imai T, Talamantes F: Opposite effects of transforming growth factor alpha and epidermal growth factor on mouse placental lactogen 1 secretion. Proc Natl Acad Sci USA 92:2830-2834, 1995