Bacterial ceramides and sphingophospholipids induce apoptosis of human leukaemic cells

Microbiology

Volumn 149, Issue 8, 2003, Pages 2071-2081

  Minamino, Miki ^a   Sakaguchi, Ikuyo ^a   Naka, Takashi ^a   Ikeda, Norikazu ^a   Kato, Yoshiko ^a   Tomiyasu, Ikuko ^b   Yano, Ikuya ^c   Kobayashi, Kazuo ^d  

^a Club Cosmetics Co Ltd   (Japan)

^b TEZUKAYAMA UNIVERSITY   (Japan)

^c Japan BCG Laboratory   (Japan)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CASPASE 3; CELL DNA; CERAMIDE; DNA FRAGMENT; FAS ANTIGEN; HYDROXY FATTY ACID; INOSITOL DERIVATIVE; PHOSPHOETHANOLAMINE; SPHINGOLIPID;

ANTIGEN EXPRESSION; APOPTOSIS; CELL CYCLE; CELL NUCLEUS; CELL STIMULATION; CELL STRUCTURE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA CLEAVAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; HYDROPHILICITY; ISOLATION PROCEDURE; LEUKEMIA CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SECOND MESSENGER; SIGNAL TRANSDUCTION; SPHINGOBACTERIUM;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SPHINGOBACTERIUM; SPHINGOBACTERIUM SPIRITIVORUM;

EID: 0042424912     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.25922-0     Document Type: Review

References (59)

1. Allan, D. (2000). Lipid metabolic changes caused by short-chain ceramides and the connection with apoptosis. Biochem J 345, 603-610.
2. Damjanovski, S., Amano, T., Li, Q., Ueda, S., Shi, Y. B. & Ishizuya-Oka, A. (2000). Role of ECM remodeling in thyroid hormone-dependent apoptosis during anuran metamorphosis. Ann N Y Acad Sci 926, 180-191.
3. Decaudin, D., Geley, S., Hirsch, T., Castedo, M., Marchetti, P., Macho, A., Kofler, R. & Kroemer, G. (1997). Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 57, 62-67.
4. Deng, G. & Podack, E. R. (1993). Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc Natl Acad Sci U S A 90, 2189-2193.
5. Eischen, C. M., Schilling, J. D., Lynch, D. H., Krammer, P. H. & Leibson, P. J. (1996). Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis. J Immunol 156, 2693-2699.
6. Ferrarini, M., Imro, M. A., Sciorati, C., Heltai, S., Protti, M. P., Pellicciari, C., Rovere, P., Manfredi, A. A. & Rugarli, C. (1999). Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes. Int J Cancer 81, 573-579.
7. Folch, J., Lees, M. & Sloane Stanley, G. H. (1959). A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226, 497-509.
8. Furuya, S., Ono, K. & Hirabayashi, Y. (1995). Sphingolipid biosynthesis is necessary for dendrite growth and survival of cerebellar Purkinje cells in culture. J Neurochem 65, 1551-1561.
9. Goodman, Y. & Mattson, M. P. (1996). Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity. J Neurochem 66, 869-872.
10. Gorczyca, W., Gong, J., Ardelt, B., Traganos, F. & Darzynkiewicz, Z. (1993). The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 53, 3186-3192.
11. Hannun, Y. A. & Obeid, L. M. (1995). Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 20, 73-77.
12. Hannun, Y. A., Loomis, C. R., Merrill, A. H., Jr & Bell, R. M. (1986). Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem 261, 12604-12609.
13. Harel, R. & Futerman, A. H. (1993). Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. J Biol Chem 268, 14476-14481.
14. Hartfield, P. J., Mayne, G. C. & Murray, A. W. (1997). Ceramide induces apoptosis in PC12 cells. FEBS Lett 401, 148-152.
15. Ishizuya-Oka, A. (1996). Apoptosis of larval cells during amphibian metamorphosis. Microsc Res Tech 34, 228-235.
16. Ito, A. & Horigome, K. (1995). Ceramide prevents neuronal programmed cell death induced by nerve growth factor deprivation. J Neurochem 65, 463-466.
17. Iwata, M., Hotta, H., Higuchi, N., Nishiuchi, N., Fujiwara, N., Arakawa, T., Yano, I. & Kobayashi, K. (2002). Induction of thymic apoptosis by shigatoxin from Escherichia coli O157:H7 in vivo and in vitro. Osaka City Med J 47, 11-22.
18. Karasavvas, N., Erukulla, R. K., Bittman, R., Lockshin, R. & Zakeri, Z. (1996). Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine. The ceramide amide group is not required for apoptosis. Eur J Biochem 236, 729-737.
19. Kawasaki, S., Moriguchi, R., Sekiya, K., Nakai, T., Ono, E., Kume, K. & Kawahara, K. (1994). The cell envelope structure of the lipopolysaccharide-lacking gram-negative bacterium Sphingomonas paucimobilis. J Bacteriol 176, 284-290.
20. Kondo, T., Matsuda, T., Tashima, M., Umehara, H., Domae, N., Yokoyama, K., Uchiyama, T. & Okazaki, T. (2000a). Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis. J Biol Chem 275, 8872-8879.
21. Kondo, T., Matsuda, T., Kitano, T. & 7 other authors (2000b). Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis. J Biol Chem 275, 7668-7676.
22. Lakics, V. & Vogel, S. N. (1998). Lipopolysaccharide and ceramide use divergent signaling pathways to induce cell death in murine macrophages. J Immunol 161, 2490-2500.
23. Lavie, Y., Cao, H., Volner, A., Lucci, A., Han, T. Y., Geffen, V., Giuliano, A. E. & Cabot, M. C. (1997). Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem 272, 1682-1687.
24. Linardic, C. M. & Hannun, Y. A. (1994). Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. J Biol Chem 269, 23530-23537.
25. Liu, P. & Anderson, R. G. (1995). Compartmentalized production of ceramide at the cell surface. J Biol Chem 270, 27179-27185.
26. Mansat, V., Laurent, G., Levade, T., Bettaieb, A. & Jaffrezou, J. P. (1997). The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Cancer Res 57, 5300-5304.
27. McConkey, D. J., Nicotera, P. & Orrenius, S. (1994). Signalling and chromatin fragmentation in thymocyte apoptosis. Immunol Rev 142, 343-363.
28. Mizushima, N., Koike, R., Kohsaka, H., Kushi, Y., Handa, S., Yagita, H. & Miyasaka, N. (1996). Ceramide induces apoptosis via CPP32 activation. FEBS Lett 395, 267-271.
29. Nakamura, S., Kozutsumi, Y., Sun, Y., Miyake, Y., Fujita, T. & Kawasaki, T. (1996). Dual roles of sphingolipids in signaling of the escape from and onset of apoptosis in a mouse cytotoxic T-cell line, CTLL-2. J Biol Chem 271, 1255-1257.
30. Nakashima, K., Ohtsuka, A. & Hayashi, K. (1998). Comparison of the effects of thyroxine and triiodothyronine on protein turnover and apoptosis in primary chick muscle cell cultures. Biochem Biophys Res Commun 251, 442-448.
31. Nakayama, M. (2000). Structure and apoptosis-inducing activity of sphingolipids isolated from Sphingobacterium spiritivorum. Seikatsu Eisei 42, 135-143.
32. Okazaki, T. (1999). Implications of "ceramide-regulating biostat system" from the discovery of "sphingomyelin cycle" [in Japanese]. Tanpakushitsu Kakusan Koso 44, 1052-1058.
33. Okazaki, T. & Domae, N. (1994). Physiological activity of sphingosine. J Clin Exp Med 171, 913-916.
34. Okazaki, T., Bell, R. M. & Hannun, Y. A. (1989). Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J Biol Chem 264, 19076-19080.
35. Okazaki, T., Bielawska, A., Bell, R. M. & Hannun, Y. A. (1990). Role of ceramide as a lipid mediator of 1 alpha, 25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem 265, 15823-15831.
36. Okazaki, T., Bielawska, A., Domae, N., Bell, R. M. & Hannun, Y. A. (1994). Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha, 25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem 269, 4070-4077.
37. Ozeki, Y., Kaneda, K., Fujiwara, N., Morimoto, M., Oka, S. & Yano, I. (1997). In vivo induction of apoptosis in the thymus by administration of mycobacterial cord factor (trehalosec 6,6′-dimycolate). Infect Immun 65, 1793-1799.
38. Parton, R. G. (1994). Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae. J Histochem Cytochem 42, 155-166.
39. Rothberg, K. G., Heuser, J. E., Donzell, W. C., Ying, Y. S., Glenney, J. R. & Anderson, R. G. (1992). Caveolin, a protein component of caveolae membrane coats. Cell 68, 673-682.
40. Saba, J. D., Obeid, L. M. & Hannun, Y. A. (1996). Ceramide: an intracellular mediator of apoptosis and growth suppression. Philos Trans R Soc Land B Biol Sci 351, 233-240; discussion 240-231.
41. Saito, T. & Kurasaki, M. (2000). Apoptosis and endocrine disrupters. Biomed Res 21, 353-359.
42. Sawai, H., Okazaki, T., Yamamoto, H. & other authors (1995). Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J Biol Chem 270, 27326-27331.
43. Schlegel, J., Peters, I., Orrenius, S., Miller, D. K., Thornberry, N. A., Yamin, T. T. & Nicholson, D. W. (1996). CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem 271, 1841-1844.
44. Schnitzer, J. E., Oh, P. & McIntosh, D. P. (1996). Role of GTP hydrolysis in fission of caveole directly from plasma membranes. Science 274, 239-242.
45. Schutze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. & Kronke, M. (1992). TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71, 765-776.
46. Schwarz, A. & Futerman, A. H. (1997). Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth. J Neurosci 17, 2929-2938.
47. Shimizu, S., Eguchi, Y., Kamiike, W., Matsuda, H. & Tsujimoto, Y. (1996). Bcl-2 expression prevents activation of the ICE protease cascade. Oncogene 12, 2251-2257.
48. Suzuki, A., Tsutomi, Y., Miura, M. & Akahane, K. (1999). Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene 18, 1239-1244.
49. Taylor, I. W. (1980). A rapid single step staining technique for DNA analysis by flow microfluorimetry. J Histochem Cytochem 28, 1021-1024.
50. Tepper, C. G., Jayadev, S., Liu, B., Bielawska, A., Wolff, R., Yonehara, S., Hannun, Y. A. & Seldin, M. F. (1995). Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A 92, 8443-8447.
51. Tessitore, L., Valente, G., Bonelli, G., Costelli, P. & Baccino, F. M. (1989). Regulation of cell turnover in the livers of tumour-bearing rats: occurrence of apoptosis. Int J Cancer 44, 697-700.
52. Verheij, M., Bose, R., Lin, X. H. & 10 other authors (1996). Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380, 75-79.
53. Wang, B., Ohyama, H., Haginoya, K., Odaka, T., Itsukaichi, H., Yukawa, O., Yamada, T. & Hayata, I. (2000). Adaptive response in embryogenesis. III. Relationship to radiation-induced apoptosis and Trp53 gene status. Radiat Res 154, 277-282.
54. Wiegmann, K., Schutze, S., Machleidt, T., Witte, O. & Kronke, M. (1994). Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78, 1005-1015.
55. Yang, Z., Costanzo, M., Golde, D. W. & Kolesnick, R. N. (1993). Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells. J Biol Chem 268, 20520-20523.
56. Yano, I., Tomiyasu, I. & Yabuuchi, E. (1982). Long chain base comparison of strains of three species of Sphingobacterium gen. nov. FEMS Microbiol Lett 15, 303-307.
57. Yano, I., Imaizumi, S., Tomiyasu, I. & Yabuuchi, E. (1983). Separation and analysis of free ceramides containing 2-hydroxy fatty acids in Sphingobacterium species. FEMS Microbiol Lett 20, 449-453.
58. Yonehara, S., Ishii, A. & Yonehara, M. (1989). A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor. J Exp Med 169, 1747-1756.
59. Zhang, Y. H., Takahashi, K., Jiang, G. Z., Kawai, M., Fukada, M. & Yokochi, T. (1993). In vivo induction of apoptosis (programmed cell death) in mouse thymus by administration of lipopolysaccharide. Infect Immun 61, 5044-5048.