Hologram quantitative structure-activity relationships investigations of non-nucleoside reverse transcriptase inhibitors

Current Medicinal Chemistry

Volumn 10, Issue 17, 2003, Pages 1661-1677

  Pungpo, Pornpan ^a,b   Hannongbua, Supa ^b   Wolschann, Peter ^c  

^a UBON RATCHATHANI UNIVERSITY   (Thailand)

^b KASETSART UNIVERSITY   (Thailand)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Dipyridodiazepinone; HEPT; HIV 1 reverse transcriptase inhibitors; HQSAR; Mutant enzyme; PLS; Quantum chemical calculations; TIBO

Indexed keywords

1 [(2 HYDROXYETHOXY)METHYL] 6 (PHENYLTHIO)THYMINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPINE DERIVATIVE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ANTIBIOTIC RESISTANCE; CALCULATION; CHEMICAL ANALYSIS; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; ENZYME INHIBITION; GEOMETRY; HOLOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS 1; PREDICTION; PROCESS OPTIMIZATION; QUALITY CONTROL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM CHEMISTRY; REVIEW; X RAY CRYSTALLOGRAPHY;

ANTI-HIV AGENTS; BENZODIAZEPINES; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; IMIDAZOLES; MOLECULAR STRUCTURE; PYRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REVERSE TRANSCRIPTASE INHIBITORS; THYMINE;

EID: 0042423431     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457106     Document Type: Review

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