A mass spectrometry study of tirapazamine and its metabolites: Insights into the mechanism of metabolic transformations and the characterization of reaction intermediates

Journal of the American Society for Mass Spectrometry

Volumn 14, Issue 8, 2003, Pages 881-892

  Zagorevskii, Dmitri ^a   Song, Minghu ^a   Breneman, Curt ^a   Yuan, Yang ^b   Fuchs, Tarra ^b   Gates, Kent S ^b   Greenlief, C Michael ^b  

^a Research Rensselaer Polytechnic Institute   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; DNA; METABOLITES; OXYGEN;

NEUTRALIZATION;

MASS SPECTROMETRY;

3 AMINO 1,2,4 BENZOTRIAZINE; 3 AMINO 1,2,4 BENZOTRIAZINE 1 OXIDE; 3 AMINO 1,2,4 BENZOTRIAZINE 2 OXIDE; 3 AMINO 1,2,4 BENZOTRIAZINE 4 OXIDE; DNA; DRUG METABOLITE; OXYGEN; TIRAPAZAMINE; UNCLASSIFIED DRUG;

MASS SPECTROMETRY; PESTICIDE;

ARTICLE; ATOM; CALCULATION; DISSOCIATION; DNA DAMAGE; ENERGY; GAS; IONIZATION; LIQUID CHROMATOGRAPHY; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; OXIDATION REDUCTION REACTION; PROTON TRANSPORT; QUANTUM CHEMISTRY; STATISTICAL SIGNIFICANCE; TANDEM MASS SPECTROMETRY;

MUS;

EID: 0042348003     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(03)00334-9     Document Type: Article

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