Sperm mitochondria of patients with normal sperm motility and with asthenozoospermia: Morphological and functional study

Folia Histochemica et Cytobiologica

Volumn 41, Issue 3, 2003, Pages 125-139

  Piasecka, Małgorzata ^a   Kawiak, Jerzy ^b  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

^b MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

Asthenozoospermia; Cytochemistry; Flow cytometry; Mitochondria; Spermatozoa; Ultrastructure

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ACCURACY; ARTICLE; ASTHENOSPERMIA; AXONEME; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; MALE; MECHANICAL PROBE; MEMBRANE POTENTIAL; MITOCHONDRION; MORPHOLOGY; OXIDATION REDUCTION POTENTIAL; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SPERM; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY;

EID: 0042312603     PISSN: 02398508     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Ahlgren G, Rannevik G, Lilja H (1995) Impaired secretory function of the prostate in men with oligo-asthenozoospermia. J Androl 16: 491-498
2. +2 in hamster sperm. Mol Perod Dev 53: 77-83
3. Balercia G, Arnaldi G, Fazioli F, Serresi M, Alleva R, Manci A, Mosca F, Lamonica GR, Mantero F, Littaru GP (2002) Coenzyme Q10 levels in idiopathic and varicocele-associated asthenozoospermia. Andrologia 34: 107-111
4. Bourgeron T (2000) Mitochondrial function and male infertility. In: Results and Problems in Cell Differentiation. The Genetic Basis of Male Infertility. McElreavey M [Ed], Springer-Verlag, Berlin-Heidelberg, pp 187-210
5. Carpino A, Sisci D, Aquila S, Salerno M, Siciliano L, Sessa M, Ando S (1994) Adnexal gland secretion markers in unexplained asthenozoospermia. Arch Androl 32: 37-43
6. Carpino A, Sicilano L, Petrone MF, De Stefano C, Aquila S, Ando S (1998) Low seminal zinc bound to high molecular weight proteins in asthenozoospermic patients: Evidence of increased sperm zinc content in oligoasthenozoospermic patients. Hum Reprod 13: 111-114
7. Chavarria E, Reyes A, Carrera A, Aguilera G, Rosado A, Veldhuis JD (1995) Kinetic study pulsatility of gonadotropin and testosterone secretion in normospermic fertile and infertile men with idiopathic oligo-asthenozoospermia. Ginecol Obstet Mex 63: 74-89
8. Check JH, Lurie D, Vetter BH (1995) Sera gonadotropins, testosterone, and prolactin levels in men with oligozoospermia or asthenozoospermia. Arch Androl 35: 57-61
9. Chemes HE, Olmedo SB, Carrere C, Oses R, Carizza C, Leisner M, Blaquier J (1998) Ultrastructural pathology of the sperm flagellum: Association between flagellar pathology and fertility prognosis to severely asthenozoosperic men. Hum Reprod 13: 2521-2526
10. Chemes HE, Puigdomenech E, Carizza C, Brugo Olmedo S, Zanchetti F, Hermes R (1999) Acephalic spermatozoa and abnormal development of the head-neck attachment. A human syndrome of genetic origin. Hum Reprod 14: 1811-1818
11. Comhaire FH, Mahmoud AM, Depuydt CE, Zalata AA, Christophe AB (1999) Mechanism and effects of male genital tract infection on sperm quality and fertilizing potential: The andrologist's viewpoint. Hum Reprod Update 5: 393-398
12. Costa M, Canale D, Filicori M, D'Iddio S, Lenzi A (1994) L-carnitine in idiopathic asthenozoospermia: A multicenter study. Italian Study Group on Carnitine and Male Infertility. Andrologia 26: 155-159
13. Courtade M, Lagorce C, Bujan L, Caratero C, Mieusset R (1998) Clinical characteristics and light transmission electron microscopic sperm defects of infertile men with persistent unexplained asthenozoospermia. Fertil Steril 70: 297-304
14. Donelly ET, O'Connell M, McClure N, Lewis EM (2000) Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa. Hum Reprod 15: 1552-1561
15. Donelly ET, Lewis SEM, McNally JA, Thompson W (1998) In vitro fertilization and pregnancy rates: The influence of sperm motility and morphology on IVF outcome. Fertil Steril 70: 305-314
16. Egozcue S, Blanco J, Vendrell JM, Garcia F, Veiga A, Aran B, Barri PN, Vidal F, Egozcue J (2000) Human male infertility: Chromosome anomalies, meiotic disorders, abnormal spermatozoa and recurrent abortion. Hum Reprod Update 6: 93-105
17. Folgero T, Bertheussen K, Lindal S, Torbengsen T, Oian P (1993) Mitochondrial disease and reduced sperm motility. Hum Reprod 8: 1863-1868
18. Gagnon C (1995) Regulation of sperm motility at the axonemal level. Reprod Fertil Dev 7: 847-855
19. Gonzales GF, Villena A (2001) True corrected seminal fructose level: A better marker of the function of seminal vesicles in infertile men. Int J Androl 24: 255-260
20. Gopalkrishnan K, Padwal V, D'Souza S, Shah R (1995) Severe asthenozoospermia: A structural and functional study. Int J Androl 18, Suppl 1: 67-74
21. Graham JK (2001) Assessment of sperm quality: A flow cytometric approach. Anim Reprod Sci 68: 239-247
22. Haugland RP (1996) Probes for organelles. In: Handbook of Fluorescent Probes and Research Chemicals. Spence MTZ [Ed], Molecular Probes, Inc, Eugene, OR, pp 266-274
23. Holstain AF, Roosen-Runge EC (1981) Atlas of Human Spermatogenesis. Vogt L [Ed], Grosse Verlag, Berlin
24. Holyoake AJ, McHugh P, Wu M, O'Carroll S (2001) High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men. Int J Androl 24: 175-182
25. Hrudka F (1979) Cytochemistry of oxidoreductases in spermatozoa: The technic revisited. Andrologia 11: 337-352
26. Imai H, Suzuki K, Ishizaka K, Ichinose S, Oshima H, Okayasu I, Emoto K, Umeda M, Nakagava Y (2001) Failure of the expression of phospholipid hydroperoxide glutathione peroxidase in the spermatozoa of human infertile males. Biol Reprod 64: 674-683
27. Irvine DS (2000) Male reproductive health: Cause for concern? Andrologia 32: 195-208
28. Ishijima S, Iwamoto T, Nozawa S, Matsushita K (2002) Motor apparatus in human spermatozoa that lack central pair microtubules. Mol Reprod Dev 63: 459-63
29. Kaskar K, Franken DR, Horst G, Oehninger S, Kruger TF, Hodgen GD (1994) The relationship between morphology, motility and zona pellucida binding potential of human spermatozoa. Andrologia 26: 1-4
30. Kret B, Milad M, Jeyendran RS (1995) New discriminatory level for glucosidase activity to diagnose epididymal obstruction or dysfunction. Arch Androl 35: 29-33
31. Kruger TF, Acosta AA, Simons KF, Swanson RJ, Matta JF, Oehninger S (1988) Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 49: 112-117
32. Lim CC, Lewis SEM, Kennedy M, Donnelly ET, Thompson W (1998) Human sperm morphology and in vitro fertilization: Sperm tail defects are prognostic for fertilization failure. Andrologia 30: 43-47
33. Luboshitzky R, Kaplan-Zverling M, Shen-Orr Z, Nave R, Herer P (2002) Seminal plasma androgen/oestrogen balance in infertile men. Int J Androl 25: 345-51
34. Luconi M, Marra F, Gandini L, Filimberti E, Lenzi A, Forti G, Baldi E (2001) Phosphatidylinositol 3-kinase inhibition enhance human sperm motility. Hum Reprod 16: 1931-1937
35. Mahmoud AM, Geslevich J, Kint J, Depuydt Ch, Huysse L, Zalata A, Comhaire FH (1998) Seminal plasma α-glucosidase activity and male infertility. Hum Reprod 13: 591-595
36. Merino G, Carranza-Lira S, Martinez-Chequer JC, Barahona E, Moran C, Bermudez JA (1997) Hyperprolactinemia in men with asthenozoospermia, oligozoospermia, or azoospermia. Arch Androl 38: 201-206
37. Morales P, Katz DF, Overstreet JW, Samuels SJ, Chang RJ The relationship between the motility and morphology of spermatozoa in human semen. J Androl 9: 241-247
38. Mundy AJ, Ryder TA, Edmonds DK (1995) Asthenozoospermia and the human sperm mid-piece. Hum Reprod 10: 116-119
39. Nagy ZP (2000) Sperm centriole disfunction and sperm immotility. Mol Cell Endocrinol 166: 59-62
40. Nakagawa Y, Imai H (2000) Novel function of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic factor. Health Sci 46: 414-417
41. Nayernia K, Adham IM, Burkhardt-Gottges E, Neesen J, Rieche M, Wolf S, Sancken U, Kleene K, Engel W (2002) Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene. Mol Cell Biol 22: 3046-3052
42. Neesen J, Kirschner R, Ochs M, Schmiedl A, Habermann B, Mueller C, Holstein AF, Nuesslein T, Adham I, Engel W (2001) Distribution of an inner arm dynein heavy gene results in asthenozoospermia and reduced ciliary beat frequency. Hum Mol Genet 10: 1117-1128
43. Nikolettos N, Kupker W, Demirel C, Schopper B, Blasing C, Sturm R, Felberbaum R, Bauer O, Diedrich K, Al-Hasani S (1999) Fertilization potential of spermatozoa with abnormal morphology. Hum Reprod 14: 47-70
44. Pedersen H, Rebbe H, Hammen R (1971) Human sperm fine structure in a case of severe asthenozoospermia. Fertil Steril 22: 156-164
45. Piasecka M, Wenda-Rózewicka L, Ogoński T (2001) Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. Andrologia 33: 1-12
46. Rawe VY, Galaverna GD, Acosta AA, Olmedo SB, Chemes HE (2001) Incidence of tail structure distortions associated with dysplasia of the fibrous sheath in human spermatozoa. Hum Reprod 16: 979-886
47. Rago V, Bilińska B, Palma A, Ando S (2003) Evidence of aromatase localization in cytoplasmic droplet of human immature ejaculated spermatozoa. Folia Histochem Cytobiol 41: 23-27
48. Rossato M, Balercia G, Lucarelli G, Foresta C, Mantero F (2002) Role of seminal osmolarity in the reduction of human sperm motility. Int J Androl 25: 230-235
49. Ruiz-Pesini E, Alvarez E, Enriquez JA, Lopez-Perez J (2001) Association between seminal plasma carnitine and sperm mitochondrial enzymatic activities. Int J Androl 24: 335-340
50. Ruiz-Pesini E, Diez C, Lapena AC, Perez-Martos A, Montoya J, Alvarez E, Arenas J, Lopez-Perez MJ (1998) Correlation of sperm motility with mitochondrial enzymatic activities. Clin Chem 44: 1616-1620
51. Ruiz-Pesini E, Lapena AC, Diez C, Alvarez E, Enriquez JA, Lopez-Perez MJ (2000) Seminal quality correlates with mitochondrial functionality. Clin Chim Acta 300: 97-105
52. Ruiz-Pesini E, Lapena AC, Diez-Sanchez C, Perez-Martos A, Montoya J, Alvarez E, Diaz M, Urries A, Montoro L, Lopez-Perez MJ, Enriquez JA (2000) Human mtDNA haplogroups associated with high or reduced spermatozoa motility. Am J Hum Genet 67: 682-686
53. Siciliano L, Tarantino P, Longobardi F, Rago V, De Stefano C, Carpino A (2001) Impaired seminal antioxidant capacity in human semen with hyperviscosity or oligoasthenozoospermia. J Androl 22: 798-803
54. Sukcharoen N, Keith J, Irvine DS, Aitken RJ (1996) Prediction of the in vitro fertilization (IVF) potential of human spermatozoa using sperm function tests: The effects of the delay between testing and IVF. Hum Reprod 11: 1030-1034
55. Suominen J (2001) Seminal fructose and glucose in asthenozoospermia. Int J Androl 24: 253-254
56. Sutowsky P, Moreno RD, Ramaldo-Santos J, Dominko T, Simerly C, Schatten G (1999) Ubiquitin tag for sperm mitochondria. Nature 402: 371-372
57. Troiano L, Antonio R, Granata M, Cossarizza A, Kalashnikova G, Bianchi R, Pini G, Tropea F, Carini C, Franceschi C (1998) Mitochondrial membrane potential and DNA stability in human sperm cells: A flow cytometry analysis with implications for male infertility. Exp Cell Res 241: 384-393
58. Trummer H, Ramschak-Schwarzer S, Haas J, Habermann H, Pummer K, Leb G (2001) Thyroid hormones and thyroid antibodies in infertile males. Fertil Steril 76: 254-267
59. Turner RM, Musse MP, Mandal A, Klotz K, Jayes FC, Herr JC, Gerton GL, Moss SB, Chemes HE (2001) Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath. J Androl 22: 302-315
60. Uma Devi K, Jha K, Patil SB, Padma P, Shivaji S (2000) Inhibition of motility of hamster spermatozoa by protein tyrosine kinase inhibitors. Andrologia 32: 95-106
61. Wei YH, Kao SH (2000) Mitochondrial DNA mutation and depletion are associated with decline of fertility and motility of human spermatozoa. Zool Stud 39: 1-12
62. WHO (1992) World Health Organization Laboratory Manual for Examination of Human Semen and Sperm-Cervical Mucus-Interaction, 3rd Ed, Cambridge University Press, Cambridge
63. Wilton LJ, Temple-Smith PD, Baker HWG, De Kretser DM (1988) Human male infertility caused by degeneration and death of sperm in the epididymis. Fertil Steril 49: 1052-1058
64. Yeung CH, Cooper TG, Nieschlag E (1997) Human epididymal secreted protein CD52 on ejaculated spermatozoa: Correlations with semen characteristics and the effect of its antibody. Mol Hum Reprod 3: 1045-1051