Inhibition of motility of hamster spermatozoa by protein tyrosine kinase inhibitors

Andrologia

Volumn 32, Issue 2, 2000, Pages 95-106

  Uma Devi, K ^a,b   Jha, K ^a   Patil, S B ^a   Padma, P ^a   Shivaji, S ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b Dr Reddy's Diagnostics Division   (India)

Author keywords

Genistein; Membrane protein tyrosine kinase; Piceatannol; Sperm motility; Tyrphostin

Indexed keywords

GENISTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; TYRPHOSTIN;

ADOLESCENT; AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME INHIBITION; FAST PROTEIN LIQUID CHROMATOGRAPHY; HAMSTER; ION EXCHANGE CHROMATOGRAPHY; MALE; MOLECULAR WEIGHT; NONHUMAN; SPERMATOZOON MOTILITY;

ANIMALS; CELL MEMBRANE; CRICETINAE; ENZYME INHIBITORS; GENISTEIN; MALE; MESOCRICETUS; PROTEIN-TYROSINE KINASES; SPERM MOTILITY; SPERMATOZOA; STILBENES; TYRPHOSTINS;

EID: 0034124322     PISSN: 03034569     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0272.2000.00331.x     Document Type: Article

References (63)

1. 2+, calmodulin and phosphoprotein phosphatases. Arch Androl 35:187-208.
2. Ain R, Uma Devi K, Shivaji S, Seshagiri PB (1999) Pentoxifylline-induced capacitation and acrosome reaction in hamster spermatozoa: mechanism of action involves intracellular signalling molecules. Mol Hum Reprod 5:618-626.
3. 2-dependent mechanism. J Reprod Fertil 105:109-114.
4. Ashizawa K, Wishart GJ, Hashimoto K, Tsuzuki Y (1995b) Dephosphorylation of a 30 kDa protein of fowl spermatozoa by the addition of myosin light chain kinase substrate peptide inhibits the flagellar motility. Biochem Biophys Res Commun 215:706-712.
5. Ashizawa K, Wishart GJ, Nishinakama K., Sakamoto T, Tsuzuki Y (1995c) Regulatory mechanisms of fowl sperm motility: possible role of enodgenous myosin light chain kinase-like protein. J Reprod Fertil 104:141-148.
6. Ashizawa K, Hashimoto K, Tsuzuki Y (1997) Regulation of fowl sperm flagellar motility by protein phosphatase Type 1 and its relationship with dephosphorylation of axonemal and/or accessory cytoskeletal proteins. Biochem Biophys Res Commun 235:108-112.
7. Ashizawa K, Higashio M, Tsuzuki Y (1998) Effects of tyrosine kinase inhibitor on the motility and ATP concentrations of fowl spermatozoa. Mol Reprod Dev 49:196-202.
8. Barua M, Bhattacharya U, Majumder GC (1985) Occurrence of an ecto-phosphoprotein phosphatase in goat epididymal spermatozoa. Biochem Int 10:733-741.
9. Bavister BD (1981) Substitution of a synthetic polymer for protein in a mammalian gamete culture system. J Exp Zool 217:45-51.
10. Bavister BD (1989) A consistently successful procedure for in vitro fertilization of golden hamster eggs. Gamete Res 23:139-158.
11. Bavister BD, Yanagimachi R (1977) The effects of sperm extracts and energy sources on the motility and acrosome reaction of hamster spermatozoa in vitro. Biol Reprod 16:228-237.
12. Berruti G (1994) Biochemical characterization of the boar sperm 42 kilodalton protein kinase: its potential for tyrosine as well as serine phosphorylation towards microtubule associated protein 2 and historic H 2B. Mol Reprod Dev 38:386-392.
13. Berruti G, Borgonovo B (1996) sp42, the boar sperm tyrosine kinase, is a male germ cell-specific product with a highly conserved tissue expression extending to other mammalian species. J Cell Sci 109:851-858.
14. Berruti G, Martegani E (1989) Identification of proteins cross-reactive to phosphotyrosine antibodies and of a tyrosine kinase activity in boar spermatozoa. J Cell Sci 93:667-674.
15. Berruti G, Porzio S (1992) Tyrosine protein kinase in boar spermatozoa. Identification and partial characterization. Biochim Biophys Acta 1118:149-154.
16. Burks J, Carballada R, Moore HDM, Saling PM (1995) Interaction of a tyrosine kinase from human sperm with the zona pellucida at fertilization. Science 269:83-86.
17. Chulavatnatol M, Panyim S, Wititsuwannakul D (1982) Comparison of phosphorylated proteins in intact rat spermatozoa from caput and cauda epididymis. Biol Reprod 26:197-207.
18. Dey CS, Brokaw CJ (1991) Activation of Ciona sperm motility: phosphorylation of dynein polypeptides and effects of a tyrosine kinase inhibitor. J Cell Sci 100:815-824.
19. Girija Devi L, Shivaji S (1994) Computerized analysis of the motility parameters of hamster spermatozoa during maturation. Mol Reprod Dev 38:94-106.
20. Haldar S, Majumder GC (1996) Comparison of phosphorylated proteins in intact rat spermatozoa from caput and cauda epididymis. Biochim Biophys Acta 887:291-303.
21. Hayashi H, Yamamoto K, Yonekawa H, Morisawa M (1987) Involvement of tyrosine protein kinase in the initiation of flagellar movement in rainbow trout spermatozoa. J Biol Chem 262:16692-16698.
22. Horowitz JB, Toeg H, Orr GA (1985) Characterization and localisation of cAMP-dependent protein kinases in rat cauda epididymal sperm. J Biol Chem 259:832-838.
23. 32P into human spermatozoa membrane components. Biol Reprod 17:9-96.
24. Jayaprakash D, Santhosh Kumar K, Shivaji S, Seshagiri PB (1997) Pentoxifylline induces hyperactivation and acrosome reaction in spermatozoa of golden hamsters: changes in motility kinematics. Hum Reprod 12:2192-2199.
25. Kalab P, Visconti P, Lecterc P, Kopf GS (1994) P95, the major phosphotyrosine containing protein in mouse spermatozoa, is a hexokinase with unique properties. J Biol Chem 299:3810-3817.
26. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
27. Leyton L, Saling P (1989) 95 kD sperm proteins bind ZP3 and serve as substrate for tyr kinase in response to zona binding. Cell 57:1123-1130.
28. Leyton L, Tomes C, Saling P (1995) LL95 monoclonal antibody mimics functional effects of ZP3 on mouse sperm: evidence that the antigen recognised is not hexokinase. Mol Reprod Dev 42:347-358.
29. Lindemann CB, Kanous KS (1989) Regulation of mammalian sperm motility. Arch Androl 23:1-22.
30. Luconi M, Krausz C, Forti G, Baldi E (1996) Extracellular calcium negatively modulates lyrosine phosphorylation and tyrosine kinase activity during capacitation of human spermatozoa. Biol Reprod 55:207-216.
31. Markwell MK, Haas SM, Bieber LL, Tolbert NE (1978) A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 87:206-210.
32. Merril CR, Goldman D, Van Keuren ML (1983) Silver staining methods for polyacrylamide gel electrophoresis. Meth Enzymol 96:230-239.
33. Mitra S, Majumder GC (1991) Alteration of the ecto-protein phosphorylation profile of intact goat spermatozoa during epididymal maturation. Biochem Int 23:611-618.
34. Morisawa M (1994) Cell signalling mechanisms for sperm motility. Zool Sci 11:647-662.
35. Morisawa M, Hayashi H (1985) Phosphorylation of a 15K axonemal protein is the trigger initiating trout sperm motility. Biomed Res 6:181-184.
36. Naz K, Ahmad K, Kumar R (1991) Role of membrane phosphotyrosine proteins in human sperm function. J Cell Sci 99:157-165.
37. Nikolopulou M, Soucek DA, Vary JC (1986) Autophosphorylation of boar sperm membranes. Biochem Int 12:815-819.
38. Noland TD, Olson GE, Garbers DL (1984) Protein phosphorylation of plasma membranes from bovine epididymal spermatozoa. Biol Reprod 31:185-194.
39. Pukazhenthi BS, Wildt DE, Ottinger MA, Howard J (1998) Inhibition of domestic cat spermatozoa aerosome reaction and zona pellucida penetration by tyrosinc kinase inhibitors. Mol Reprod Dev 49:48-57.
40. Rotem R, Paz GF, Homonnai ZT, Kalina M, Naor Z (1990a) Protein kinase C is present in human sperm: possible role in fiagellar motility. Proc Natl Acad Sci USA 87:7305-7308.
41. Rotem R, Paz GF, Homonnai ZT, Kalina M, Naor Z (1990b) Further studies on the involvement of protein kinase C in human sperm fiagellar motility. Endocrinology 127: 2571-2577.
42. Shivaji S, Jagannadham MV (1992) Steroid-induced perturbation of membranes and its relevance to sperm aerosome reaction. Biochim Biophys Acta 1108:99-109.
43. Shivaji S, Peedicayil J, Girija Devi L (1995) Analysis of the motility parameters of in vitro hyperactivated hamster spermatozoa. Mol Report Dev 42:233-247.
44. Smith GD, Wolf DP, Trautman KG, Cruz e Silva EFD, Greengard P, Vijayaraghavan S (1996) Primate sperm contain protein phosphatase 1, a biochemical mediator of motility. Biol Reprod 54:719-727.
45. Smith GD, Wolf DP, Trautman KG, Vijayaraghavan S (1999) Motility potential of Macaque epididymal sperm: the role of protein phosphatase and glycogen synthase kinase-3-activities. J Androl 20:47-53.
46. Suarez SS (1988) Hamster sperm motility transformation during development of hyperactivation in vitro and epididymal maturation. Gamete Res 19:51-65.
47. Tang FY, Hoskins DD (1975) Phosphoprotein phosphatase of bovine epididymal sperm. Biochem Biophys Res Commun 62:328-335.
48. Tash JS, Bracho GE (1994) Regulation of sperm motility: emerging evidence for a major role for protein phosphatases. J Androl 15:505-509.
49. Tash JS, Means AR (1983) Cyclic adenosine 3′,5′-monophosphate, calcium and protein phosphorylation in flagellar motility. Biol Reprod 28:75-104.
50. Tash JS, Krinis M, Patel J, Means RL, Klee CB, Means AR (1988) Identification, characterisation and functional correlations of calmodulin-dependent protein phosphatase in sperm. J Cell Biol 106:1625-1633.
51. Uma Devi K, Basheer Ahmad M, Shivaji S (1996) Acrosome membrane associated protein kinase activity in hamster spermatozoa. FEBS Lett 396:123-126.
52. Uma Devi K, Basheer Ahmad M, Shivaji S (1997) A maturation related differential phosphorylation of the plasma membrane proteins of the epididymal spermatozoa of hamster by endogenous protein kinases. Mol Reprod Dev 47:341-350.
53. Uma Devi K, Jha, K, Shivaji S (1999) Plasma membrane-associated protein tyrosine phosphatase activity in hamster spermatozoa. Mol Reprod Dev 53:42-50.
54. 2+ ATPase activity in bull sperm. FEBS Lett 114:45-47.
55. Vijayasarathy S, Shivaji S, Balaram P (1982) Bull sperm plasma and acrosomal membranes: fluorescence studies on lipid phase fluidity. Biochem Biophys Res Commun 108:585-591.
56. Vijayaraghavan S, Stephens DT, Trautman K, Smith GD, Khatra B, Cruz e Silva EDF, Greengard P (1996) Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity. Biol Reprod 54:709-718.
57. Vijayaraghavan S, Trautman K.D, Goueli SA, Carr DW (1997) A tyrosine phosphorylated 55-kilodalton motility-associated bovine sperm protein is regulated by cyclic adenosine 3′-5′-monophosphates and calcium. Biol Reprod 56:1450-1457.
58. Visconti PE, Bailey JE, Moore GD, Pan D, Olds-Clarke P, Kopf GS (1995) Capacitation of mouse spermatozoa I. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 121:1129-1137.
59. Visconti PE, Galantino-Homer H, Moore GD, Bailey JL, Ning X, Fornes M, Kopf GS (1998) The molecular basis of sperm capacitation. J Androl 19:242-248.
60. Wardlaw AC (1985) Practical Statistics for Experimental Biologists. John Wiley & Sons, New York, pp. 43-53, 141-162.
61. Wooten MW, Voglmayr JK, Wrenn RW (1987) Characterizatioon of cAMP-dependent protein kinase and its endogenous substrate proteins in ram testicular cauda epididymal and ejaculated spermatozoa. Gamete Res 16:57-68.
62. Yeoung CH (1984) Effects of cyclic-AMP on the motility of mature and immature hamster epididymal spermatozoa studied by reactivation of the demembranated cells. Gamete Res 9:99-114.
63. Zahler WL, Doak GA (1975) Isolation of the outer acrosomal membrane from bull sperm. Biochem Biophys Ada 406:479-488.