Human epididymal secreted protein CD52 on ejaculated spermatozoa: Correlations with semen characteristics and the effect of its antibody

Molecular Human Reproduction

Volumn 3, Issue 12, 1997, Pages 1045-1051

  Yeung, C H ^a   Cooper, T G ^a   Nieschlag, E ^a  

^a INST OF REPRO MED OF THE UNIV   (Germany)

Author keywords

Asthenozoospermia; CAMPATH 1; Epididymal secretion; Glycosylphosphatidylinositol anchor; Sperm motility

Indexed keywords

CAMPATH 1G; CD52 ANTIGEN; GLYCOPROTEIN; HIGH DENSITY LIPOPROTEIN; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; TUMOR ANTIGEN;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; EJACULATION; EPIDIDYMIS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; METABOLISM; PHYSIOLOGY; SECRETION; SPERM; SPERMATOZOON; SPERMATOZOON MOTILITY; STAINING;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, NEOPLASM; EJACULATION; EPIDIDYMIS; GLYCOPROTEINS; HUMANS; LIPOPROTEINS, HDL; MALE; SEMEN; SPERM MOTILITY; SPERMATOZOA; STAINING AND LABELING;

EID: 0031297197     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/3.12.1045     Document Type: Article

References (35)

1. Boué, F. and Sullivan, R. (1996) Cases of human infertility are associated with the absence of P34H, an epididymal sperm antigen. Biol. Reprod., 54, 1018-1024.
2. Boué, F., Duquenne, C., Lassalle, B. et al (1995) FLB1, a human protein of epididymal origin that is involved in the sperm- oocyte recognition process. Biol. Reprod., 52, 267-278.
3. Boué, F., Blais, J. and Sullivan, R. (1996) Surface localization of P34H, an epididymal protein, during maturation, capacitation, and acrosome reaction of human spermatozoa. Biol. Reprod., 54, 1009-1017.
4. Cooper, T.G. (1995a) Role of the epididymis in mediating changes in the male gamete during maturation. In Mukhopadhyay, A K. and Raizada, M.K. (eds), Tissue Renin-Angiotensin Systems. Current Concepts of Local Regulators in Reproductive and Endocrine Organs. Advances in Experimental Medicine and Biology. Plenum Press, New York, pp. 87-101.
5. Cooper, T.G. (1995b) The epididymal influence on sperm maturation. Reprod. Med. Rev., 4, 141-161.
6. Cooper, T.G. and Yeung, C.H. (1997) Physiology of male reproduction and fertilization. In Nieschlag, E. and Behre, H.M. (eds), Andrology, Male Reproductive Health and Dysfunction. Springer, Berlin, pp. 61-78.
7. Eccleston, E.D., White, T.W., Howard, J.B. and Hamilton, D.W. (1994) Characterization of a cell surface glycoprotein associated with maturation of rat spermatozoa. Mol. Reprod. Dev., 37, 110-119.
8. Ettenger, R.B. and Yadin, O. (1995) The potential role of therapeutic antibodies in the regulation of rejection. Transplant Proc., 27 (Suppl. 1). 13-17.
9. Hale, G. (1995) Synthetic peptide mimotope of the CAMPATH-1 (CD52) antigen, a small glycosylphosphatidylinositol-anchored glycoprotein. Immunotechnology, 1, 175-187.
10. Hale, G., Dyer, M.J.S., Clark, M.R. et al. (1988) Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody. Lancet, ii, 1394-1399.
11. Hale, G., Rye, P.D., Warford, A. et al ( 1993) The glycosylphosphatidylinositol-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa. J. Reprod. Immunol., 23, 189-20.
12. Hale, C., Bartholomew, M., Taylor, V. et al. (1996) Recognition of CD52 allelic gene products by CAMPATH-1H antibodies. Immunology, 88, 183-190.
13. Hayashi, M., Fujimoto, S., Takano, H. et al. (1996) Characterization of a human glycoprotein with a potential role in sperm-egg fusion: cDNA cloning, immunohistochemical localization, and chromosomal assignment of the gene AEGLI. Genomics, 32, 367-374.
14. Hutter, H., Hammer, A., Blaschitz, A. et al. (1996) The monoclonal antibody GZS-1 detects a maturation-associated antigen of human spermatozoa that is also present on the surface of human mononuclear blood cells. J. Reprod. Immunol., 30, 115-132.
15. Kirchhoff, C. (1994) A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen. Biol. Reprod., 50, 896-902.
16. Kirchhoff, C (1995) Molecular biology of sperm maturation in the human epididymis. Reprod. Med. Rev., 4, 121-139.
17. Kirchhoff, C. (1996) CD52 is the 'major maturation-associated' sperm membrane antigen. Mol. Hum. Reprod., 2, 9-17.
18. Kirchhoff, C. and Hale, G. (1996) Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation. Mol. Hum. Reprod., 2, 177-184.
19. Kirchhoff, C., Habben, I., Ivell, R. and Krull, N. (1991) A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. Biol. Reprod., 45, 350-357.
20. Kirchhoff, C., Krull, N., Pera, I. and Ivell, R. (1993) A major mRNA of the human epididymis principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone. Mol Reprod. Dev., 34, 8-15.
21. Kooyman, D.L., Byrne, GW., McClellan, S. et al. (1995) In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium. Science, 269, 89-92.
22. Kràtzschmar, J., Haendler, B., Eberspaecher, U. et al. (1996) The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. Eur. J. Biochem., 236, 827-836.
23. Krull, N., Ivell, R., Osterhoff, C. and Kirchhoff, C. (1993) Region-specific variation of gene expression in the human epididymis as revealed by in situ hybridization with tissue-specific cDNAs. Mol. Reprod. Dev., 34, 16-24.
24. Rochwerger, L. and Cuasnicú, P.S. (1992) Redistribution of a rat sperm epididymal glycoprotein after in vitro and in vivo capacitation. Mol. Reprod. Dev., 31, 34-41.
25. Rooney, I.A., Atkinson, J.P, Krul, E.S., et al. (1993) Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediates lysis. J. Exp Med., 177, 1409-1420.
26. Rooney, I.A., Heuser, J.E. and Atkinson, J P. (1996) GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells. J. Clin. Invest., 97, 1675-1686.
27. Väkevä. A , Jauhiainen, M., Ehnholm, C. et al (1994) High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma. Immunology, 82, 28-33.
28. Valentin, H., Celin, C., Coulombel, L. et al. (1992) The distribution of the CDw52 molecule on blood cells and characterization of its involvement in T cells activation Transplantation. 54, 97-104.
29. WHO (1992) Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 3rd edn. Cambridge University Press, Cambridge.
30. Xia, M.-Q., Tone, M., Packman, L. et al. (1991) Characterization of the CAMPATH (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. Eur. J. Immunol., 21, 1677-1684.
31. Xia, M.-Q., Hales, G., Lifely, M.R. et al. (1993) Structure of the CAMPATH-1 antigen, a glycosylphosphatidyinositol anchored glycoprotein which is an exceptionally good target for complement lysis. Biochem. J., 293, 633-640.
32. Yeung, C.H., Cooper, T.G., Oberpenning, F. et al. (1993) Changes in movement characteristics of human spermatozoa along the length of the epididymis. Biol. Reprod., 49, 274-280.
33. Yeung, C.H., Majumder, G.C., Rolf, C. et al. (1996) The role of phosphocreatine kinase in the motility of human spermatozoa supported by different metabolic substrates. Mol. Hum. Reprod., 2, 591-596.
34. Yeung, C.H., Schröter, S., Wagenfeld, A et al. (1997) Interaction of the human epididymal protein CD52 (HE5) with epididymal spermatozoa from men and cynomolgus monkeys. Mol Reprod Dev., 48, 267-275.
35. Zeheb, R. and Orr, G.A. (1984) Characterization of a maturation-associated glycoprotein on the plasma membrane of rat caudal epididymal sperm. J. Biol. Chem., 259, 839-848.