Inhibition of calcium/calmodulin-dependent protein kinase II normalizes diabetes-induced abnormal vascular reactivity in the rat perfused mesenteric vascular bed

Autonomic and Autacoid Pharmacology

Volumn 23, Issue 1, 2003, Pages 27-33

  Yousif, M H M ^a   Benter, I F ^a   Akhtar, S ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Angiotensin II; Calcium calmodulin dependent protein kinase II; Carbachol; Diabetes; Endothelin 1; Histamine; KN 93; Mesenteric bed; Noradrenaline; Vascular dysfunction

Indexed keywords

ANGIOTENSIN; CARBACHOL; ENDOTHELIN 1; GLUCOSE; HISTAMINE; INSULIN; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NORADRENALIN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; STREPTOZOCIN; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC ANGIOPATHY; ENZYME INHIBITION; FEMALE; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; MESENTERY BLOOD FLOW; NONHUMAN; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; WEIGHT REDUCTION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DIABETES MELLITUS, EXPERIMENTAL; ENZYME INHIBITORS; FEMALE; MESENTERIC ARTERIES; MESENTERIC VEINS; PERFUSION; RATS; RATS, WISTAR; SPLANCHNIC CIRCULATION; VASODILATION;

EID: 0042244172     PISSN: 14748665     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1474-8673.2003.00282.x     Document Type: Article

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