-
2
-
-
0034703742
-
P53: Death star
-
Vousden K.H. p53: death star. Cell. 103:2000;691-694.
-
(2000)
Cell
, vol.103
, pp. 691-694
-
-
Vousden, K.H.1
-
3
-
-
0028353711
-
Multifactorial analysis of p53 alteration in human cancer: A review
-
Soussi T., Legros Y., Lubin R., Ory K., Schlichtholz B. Multifactorial analysis of p53 alteration in human cancer: a review. Int. J. Cancer. 57:1994;1-9.
-
(1994)
Int. J. Cancer
, vol.57
, pp. 1-9
-
-
Soussi, T.1
Legros, Y.2
Lubin, R.3
Ory, K.4
Schlichtholz, B.5
-
4
-
-
0027489384
-
Clinical implications of the p53 tumor-suppressor gene
-
Harris C.C., Hollstein M. Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med. 329:1993;1318-1327.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
5
-
-
0027109075
-
Cancer p53, guardian of the genome
-
Lane D.P. Cancer p53, guardian of the genome. Nature. 358:1992;15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
7
-
-
0030460978
-
The p53 response to ionising radiation in adult and developing murine tissues
-
Maccallum D.E., Hupp T.R., Midgley C.A., Stuart D., Campbell S.J., Harper A., Walsh F.S., Wright E.G., Balmain A., Lane D.P., Hall P.A. The p53 response to ionising radiation in adult and developing murine tissues. Oncogene. 13:1996;2575-2587.
-
(1996)
Oncogene
, vol.13
, pp. 2575-2587
-
-
Maccallum, D.E.1
Hupp, T.R.2
Midgley, C.A.3
Stuart, D.4
Campbell, S.J.5
Harper, A.6
Walsh, F.S.7
Wright, E.G.8
Balmain, A.9
Lane, D.P.10
Hall, P.A.11
-
8
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan M.B., Zhan Q., El-Deiry W.S., Carrier F., Jacks T., Walsh W.V., Plunkett B.S., Vogelstein B., Fornace A.J. Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell. 71:1992;587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace A.J., Jr.9
-
9
-
-
0028171182
-
The p53-dependent G1 cell cycle checkpoint pathway and ataxia- telangiectasia
-
Canman C.E., Wolff A.C., Chen C.Y., Fornace A.J. Jr., Kastan M.B. The p53-dependent G1 cell cycle checkpoint pathway and ataxia- telangiectasia. Cancer Res. 54:1994;5054-5058.
-
(1994)
Cancer Res.
, vol.54
, pp. 5054-5058
-
-
Canman, C.E.1
Wolff, A.C.2
Chen, C.Y.3
Fornace A.J., Jr.4
Kastan, M.B.5
-
10
-
-
0028221013
-
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
-
Chen C.Y., Oliner J.D., Zhan Q., Fornace A.J. Jr., Vogelstein B., Kastan M.B. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc. Natl. Acad. Sci. USA. 91:1994;2684-2688.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2684-2688
-
-
Chen, C.Y.1
Oliner, J.D.2
Zhan, Q.3
Fornace A.J., Jr.4
Vogelstein, B.5
Kastan, M.B.6
-
11
-
-
0027298576
-
Induction of cellular p53 activity by DNA-damaging agents and growth arrest
-
Zhan Q., Carrier F., Fornace A.J. Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell Biol. 13:1993;4242-4250.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 4242-4250
-
-
Zhan, Q.1
Carrier, F.2
Fornace A.J., Jr.3
-
12
-
-
0027500246
-
Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
-
Fritsche M., Haessler C., Brandner G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene. 8:1993;307-318.
-
(1993)
Oncogene
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brandner, G.3
-
13
-
-
0027212267
-
Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents
-
Tishler R.B., Calderwood S.K., Coleman C.N., Price B.D. Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. Cancer Res. 53:1993;2212-2216.
-
(1993)
Cancer Res.
, vol.53
, pp. 2212-2216
-
-
Tishler, R.B.1
Calderwood, S.K.2
Coleman, C.N.3
Price, B.D.4
-
14
-
-
0031987277
-
Regulation of p53 downstream genes
-
El-Deiry W.S. Regulation of p53 downstream genes. Semin. Cancer Biol. 8:1998;345-357.
-
(1998)
Semin. Cancer Biol.
, vol.8
, pp. 345-357
-
-
El-Deiry, W.S.1
-
15
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
16
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., Yamashita T., Tokino T., Taniguchi T., Tanaka N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 288:2000;1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
17
-
-
0034664733
-
P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by ser-46-phosphorylated p53
-
Oda K., Arakawa H., Tanaka T., Matsuda K., Tanikawa C., Mori T., Nishimori H., Tamai K., Tokino T., Nakamura Y., Taya Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by ser-46-phosphorylated p53. Cell. 102:2000;849-862.
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
18
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J., Zhang L., Hwang P.M., Kinzler K.W., Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol. Cell. 7:2001;673-682.
-
(2001)
Mol. Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
19
-
-
0030063855
-
Allelotype of salivary gland tumors
-
Johns III M.M., Westra W.H., Califano J.A., Eisele D., Koch W.M., Sidransky D. Allelotype of salivary gland tumors. Cancer Res. 56:1996;1151-1154.
-
(1996)
Cancer Res.
, vol.56
, pp. 1151-1154
-
-
Johns III, M.M.1
Westra, W.H.2
Califano, J.A.3
Eisele, D.4
Koch, W.M.5
Sidransky, D.6
-
20
-
-
0028350523
-
Allelotype of head and neck squamous cell carcinoma
-
Nawroz H., Van Der Riet P., Hruban R.H., Koch W., Ruppert J.M., Sidransky D. Allelotype of head and neck squamous cell carcinoma. Cancer Res. 54:1994;1152-1155.
-
(1994)
Cancer Res.
, vol.54
, pp. 1152-1155
-
-
Nawroz, H.1
Van Der Riet, P.2
Hruban, R.H.3
Koch, W.4
Ruppert, J.M.5
Sidransky, D.6
-
21
-
-
0025652870
-
Chromosome alterations in 21 non-small cell lung carcinomas
-
Miura I., Siegfried J.M., Resau J., Keller S.M., Zhou J.Y., Testa J.R. Chromosome alterations in 21 non-small cell lung carcinomas. Genes Chromosomes Cancer. 2:1990;328-338.
-
(1990)
Genes Chromosomes Cancer
, vol.2
, pp. 328-338
-
-
Miura, I.1
Siegfried, J.M.2
Resau, J.3
Keller, S.M.4
Zhou, J.Y.5
Testa, J.R.6
-
22
-
-
0030799819
-
Genomic alterations in nasopharyngeal carcinoma: Loss of heterozygosity and Epstein-Barr virus infection
-
Mutirangura A., Tanunyutthawongese C., Pornthanakasem W., Kerekhanjanarong V., Sriuranpong V., Yenrudi S., Supiyaphun P., Voravud N. Genomic alterations in nasopharyngeal carcinoma: loss of heterozygosity and Epstein-Barr virus infection. Br. J. Cancer. 76:1997;770-776.
-
(1997)
Br. J. Cancer.
, vol.76
, pp. 770-776
-
-
Mutirangura, A.1
Tanunyutthawongese, C.2
Pornthanakasem, W.3
Kerekhanjanarong, V.4
Sriuranpong, V.5
Yenrudi, S.6
Supiyaphun, P.7
Voravud, N.8
-
23
-
-
0035866332
-
Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers
-
Sanchez-Cespedes M., Ahrendt S.A., Piantadosi S., Rosell R., Monzo M., Wu L., Westra W.H., Yang S.C., Jen J., Sidransky D. Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers. Cancer Res. 61:2001;1309-1313.
-
(2001)
Cancer Res.
, vol.61
, pp. 1309-1313
-
-
Sanchez-Cespedes, M.1
Ahrendt, S.A.2
Piantadosi, S.3
Rosell, R.4
Monzo, M.5
Wu, L.6
Westra, W.H.7
Yang, S.C.8
Jen, J.9
Sidransky, D.10
-
24
-
-
0036682309
-
Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance
-
Wong M.P., Lam W.K., Wang E., Chiu S.W., Lam C.L., Chung L.P. Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance. Cancer Res. 62:2002;4464-4468.
-
(2002)
Cancer Res.
, vol.62
, pp. 4464-4468
-
-
Wong, M.P.1
Lam, W.K.2
Wang, E.3
Chiu, S.W.4
Lam, C.L.5
Chung, L.P.6
-
25
-
-
0029836445
-
Microsatellite alterations in serum DNA of head and neck cancer patients
-
Nawroz H., Koch W., Anker P., Stroun M., Sidransky D. Microsatellite alterations in serum DNA of head and neck cancer patients. Nat. Med. 2:1996;1035-1037.
-
(1996)
Nat. Med.
, vol.2
, pp. 1035-1037
-
-
Nawroz, H.1
Koch, W.2
Anker, P.3
Stroun, M.4
Sidransky, D.5
-
26
-
-
0033595018
-
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array
-
Ahrendt S.A., Halachmi S., Chow J.T., Wu L., Halachmi N., Yang S.C., Wehage S., Jen J., Sidransky D. Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. Proc. Natl. Acad. Sci. USA. 96:1999;7382-7387.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7382-7387
-
-
Ahrendt, S.A.1
Halachmi, S.2
Chow, J.T.3
Wu, L.4
Halachmi, N.5
Yang, S.C.6
Wehage, S.7
Jen, J.8
Sidransky, D.9
-
27
-
-
0035265686
-
Novel proapoptotic gene, is induced by p53
-
Nakano K., Vousden P.U.M.A. novel proapoptotic gene, is induced by p53. Mol. Cell. 7:2001;683-694.
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, P.U.M.A.2
-
28
-
-
0025782858
-
Identification of p53 gene mutations in bladder cancers and urine samples
-
Sidransky D., Von Eschenbach A., Tsai Y.C., Jones P., Summerhayes I., Marshall F., Paul M., Green P., Hamilton S.R., Frost P., et al. Identification of p53 gene mutations in bladder cancers and urine samples. Science. 252:1991;706-709.
-
(1991)
Science
, vol.252
, pp. 706-709
-
-
Sidransky, D.1
Von Eschenbach, A.2
Tsai, Y.C.3
Jones, P.4
Summerhayes, I.5
Marshall, F.6
Paul, M.7
Green, P.8
Hamilton, S.R.9
Frost, P.10
-
29
-
-
0029091503
-
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
-
Cairns P., Polascik T.J., Eby Y., Tokino K., Califano J., Merlo A., Mao L., Herath J., Jenkins R., Westra W., et al. Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nat. Genet. 11:1995;210-212.
-
(1995)
Nat. Genet.
, vol.11
, pp. 210-212
-
-
Cairns, P.1
Polascik, T.J.2
Eby, Y.3
Tokino, K.4
Califano, J.5
Merlo, A.6
Mao, L.7
Herath, J.8
Jenkins, R.9
Westra, W.10
-
30
-
-
0029011539
-
CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A., Herman J.G., Mao L., Lee D.J., Gabrielson E., Burger P.C., Baylin S.B., Sidransky D. CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med. 1:1995;686-692.
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
31
-
-
0028881595
-
Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer
-
Li Y.J., Laurent-Puig P., Salmon R.J., Thomas G., Hamelin R. Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer. Oncogene. 10:1995;599-601.
-
(1995)
Oncogene
, vol.10
, pp. 599-601
-
-
Li, Y.J.1
Laurent-Puig, P.2
Salmon, R.J.3
Thomas, G.4
Hamelin, R.5
-
32
-
-
0034146203
-
Absence of p21 WAF1 and p27 kip1 gene mutations in various feline tumours
-
Mayr B., Wilhelm B., Reifinger M., Brem G. Absence of p21 WAF1 and p27 kip1 gene mutations in various feline tumours. Vet. Res. Commun. 24:2000;115-124.
-
(2000)
Vet. Res. Commun.
, vol.24
, pp. 115-124
-
-
Mayr, B.1
Wilhelm, B.2
Reifinger, M.3
Brem, G.4
-
33
-
-
0027940495
-
Absence of WAF1 mutations in a variety of human malignancies
-
Shiohara M., El-Deiry W.S., Wada M., Nakamaki T., Takeuchi S., Yang R., Chen D.L., Vogelstein B., Koeffler H.P. Absence of WAF1 mutations in a variety of human malignancies. Blood. 84:1994;3781-3784.
-
(1994)
Blood
, vol.84
, pp. 3781-3784
-
-
Shiohara, M.1
El-Deiry, W.S.2
Wada, M.3
Nakamaki, T.4
Takeuchi, S.5
Yang, R.6
Chen, D.L.7
Vogelstein, B.8
Koeffler, H.P.9
-
34
-
-
0033989261
-
Mutation of BAX occurs infrequently in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas
-
Gaidano G., Vivenza D., Forconi F., Capello D., Gloghini A., Bhatia K., Gutierrez M., Gallicchio M., Avanzi G.C., Fassone L., Ariatti C., Buonaiuto D., Cingolani A., Saglio G., Tirelli U., Larocca L.M., Dalla-Favera R., Carbone A. Mutation of BAX occurs infrequently in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. Genes Chromosomes Cancer. 27:2000;177-182.
-
(2000)
Genes Chromosomes Cancer
, vol.27
, pp. 177-182
-
-
Gaidano, G.1
Vivenza, D.2
Forconi, F.3
Capello, D.4
Gloghini, A.5
Bhatia, K.6
Gutierrez, M.7
Gallicchio, M.8
Avanzi, G.C.9
Fassone, L.10
Ariatti, C.11
Buonaiuto, D.12
Cingolani, A.13
Saglio, G.14
Tirelli, U.15
Larocca, L.M.16
Dalla-Favera, R.17
Carbone, A.18
-
35
-
-
0033762237
-
Bax mutations are an infrequent event in indolent lymphomas and in mantle cell lymphoma
-
Martini M., D'alo F., Pierconti F., Ricci R., Capelli A., Leone G., Larocca L.M. Bax mutations are an infrequent event in indolent lymphomas and in mantle cell lymphoma. Haematologica. 85:2000;1019-1023.
-
(2000)
Haematologica
, vol.85
, pp. 1019-1023
-
-
Martini, M.1
D'alo, F.2
Pierconti, F.3
Ricci, R.4
Capelli, A.5
Leone, G.6
Larocca, L.M.7
-
36
-
-
0032445618
-
Infrequent Bax gene mutations in B-cell lymphomas
-
Peng H., Aiello A., Packham G., Isaacson P.G., Pan L. Infrequent Bax gene mutations in B-cell lymphomas. J. Pathol. 186:1998;378-382.
-
(1998)
J. Pathol.
, vol.186
, pp. 378-382
-
-
Peng, H.1
Aiello, A.2
Packham, G.3
Isaacson, P.G.4
Pan, L.5
-
37
-
-
0036645286
-
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
-
Sanchez-Cespedes M., Parrella P., Esteller M., Nomoto S., Trink B., Engles J.M., Westra W.H., Herman J.G., Sidransky D. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. Cancer Res. 62:2002;3659-3662.
-
(2002)
Cancer Res.
, vol.62
, pp. 3659-3662
-
-
Sanchez-Cespedes, M.1
Parrella, P.2
Esteller, M.3
Nomoto, S.4
Trink, B.5
Engles, J.M.6
Westra, W.H.7
Herman, J.G.8
Sidransky, D.9
|