Genomic alterations in nasopharyngeal carcinoma: Loss of heterozygosity and Epstein-Barr virus infection

British Journal of Cancer

Volumn 76, Issue 6, 1997, Pages 770-776

  Mutirangura, A ^a   Tanunyutthawongese, C ^a   Pornthanakasem, W ^a   Kerekhanjanarong, V ^a   Sriuranpong, V ^a   Yenrudi, S ^a   Supiyaphun, P ^a   Voravud, N ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Allelotype; Epstein Barr virus; Loss of heterozygosity; Nasopharyngeal carcinoma; Tumour suppressor gene

Indexed keywords

MICROSATELLITE DNA;

ARTICLE; CARCINOGENESIS; CHROMOSOMAL LOCALIZATION; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 14Q; CHROMOSOME 16Q; CHROMOSOME 19Q; CHROMOSOME 22Q; CHROMOSOME 3P; CHROMOSOME 3Q; CHROMOSOME 6P; CHROMOSOME 9P; CHROMOSOME 9Q; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; EPSTEIN BARR VIRUS; GENE MUTATION; HEAD CANCER; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; NASOPHARYNX CARCINOMA; NECK CANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE; VIRUS INFECTION;

EID: 0030799819     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.460     Document Type: Article

References (39)

1. Brennan JA, Mao L, Hruban RH, Boyle JO, Eby YJ, Koch WM, Goodman SN and Sidransky D (1995) Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 332: 429-435
2. Broder S and Karp JE (1995) Progress against cancer (Review). J. Cancer Res Clin Oncol 121: 633-647
3. Boyle JO, Hakim J, Koch W, van der Riet P, Hruban RH, Roa RA, Correo R, Eby YJ, Ruppert JM and Sidransky D (1993) The incidence of p53 mutations increases with progression of head and neck. Cancer Res 53: 4477-4480
4. Carson DA and Lois A (1995) Cancer progression and p53 (Review). Lancer 346: 1009-1011
5. Chakrani F, Armand J-P, Lenoir G, Ju L, Liang J-P, May E and May P (1995) Mutations clustered in exon 5 of the p53 gene in primary nasopharyngeal carcinomas from southeastern Asia. Int J Cancer 61: 316-320
6. Chang WY, Cairns P, Schoenberg MP, Polascik TJ and Sidransky D (1995) Novel suppressor loci on chromosome 14q in primary bladder cancer. Cancer Res 55: 3246-3249
7. Choi PHK, Suen MWM, Huang DP, Lo K-W and Lee JCK (1993) Nasopharyngeal carcinoma: genetic changes, Epstein-Barr virus infection, or both. Cancer 15: 2873-2878
8. El-Naggar AK, Hurr K, Batsakis JG, Luna MA, Goepfert H and Huff V (1995) Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. Cancer Res 55: 2656-2659
9. Fandi A, Altun M, Azli N, Armand JP and Cvitkovic E (1994) Nasopharyngeal cancer: epidemiology, staging and treatment. Semin Oncol 21: 382-397
10. Feinmesser R, Miyazaki I, Cheung R, Freeman JL, Noyek AM and Dosch H-M (1992) Diagnosis of nasopharyngeal carcinoma by DNA amplification of tissue obtained by fine-needle aspiration. N Engl J Med 326: 17-21
11. Field JK, Spandidos DA, Malliri A, Gosney JK, Yiagnisis M and Stell PM (1991) Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. Br J Cancer 64: 573-577
12. Field JK, Kiaris H, Risk JM, Tsiriyotis C, Adamson R, Zoumpourlis V, Rowley H, Taylor K, Whittaker J, Howard P, Beirne JC, Gosney JR, Woolgar J, Vaughan ED, Spandidos DA and Jones AS (1995) Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival. Br J Cancer 72: 1180-1188
13. Fong CT, White PS, Peterson K, Sapienza C, Cavenee WK, Kern SE, Vogelstein B, Cantor AB, Look AT and Brodeur GM (1992) Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas. Cancer Res 52: 1780-1785
14. Gudmundsson J, Barkardottir RB, Eiriksdottir G, Baldursson T, Arason A, Egilsson V and Ingvarsson S (1995a) Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations. Br J Cancer 72: 696-701
15. Gudmundsson J, Johannesdottir G, Bergthorsson JT, Arason A, Ingvarsson S, Egilsson V and Barkardottir RB (1995b) Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13. Cancer Res 55: 4830-4832
16. Huang DP, Lo KW, Choi PH, Ng AY, Yin GK and Lee JC (1991) Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinoma. Cancer Genetics Cytogenetics 54: 91-99
17. Huang DP, Lo K-W, Van Hasselt A, Woo JKS, Choi PHK, Leung S-F, Cheung S-T, Cairns P, Sidransky D and Lee JCK (1994) A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma. Cancer Res 54: 4003-4006
18. Hui ABY, Lo K-W, Leung S-F, Choi PHK, Fong Y, Lee JCK and Huang DP (1996) Loss of heterozygosity on the long arm of chromosome 11 in nasopharyngeal carcinoma. Cancer Res 56: 3225-3229
19. Iizuka M, Sugiyama Y, Shiraishi M, Jones C and Sekiya T (1995) Allelie losses in human chromosome 11 in lung cancers. Genes Chromosomes Cancer 13: 40-46
20. Knudson AG JR (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820
21. Latif F, Tory K, Gnarra J, Yao M, Duh FM, Orcutt ML, Stackhouse T, Kuzmin I, Modi W, Geil L, Schmidt L, Zhou F, Li H, Wei MH, Chen F, Glenn G, Choyke P, Walther MM, Weng Y, Duan D-SR, Dean M, Glavac D, Richards FM, Crossey PA, Ferguson-Smith MA, Le Paslier D, Chumakov I, Cohen D, Chinault AC, Maher ER, Linehan WM, Zbar B and Lerman M (1993) Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260: 1317-1320
22. Liebowitz D (1994) Nasopharyngeal carcinoma: the Epstein-Barr virus association. Semin Oncol 21: 376-381
23. Lin J-C, Lin S-C, De BK, Chan W-P and Evatt BL (1993) Precision of genotyping of Epstein-Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease. Blood 81: 3372-3381
24. Lo K-W, Huang DP and Lau KM (1995) P16 gene alterations in nasopharyngeal carcinoma. Cancer Res 55: 2039-2043
25. Lo K-W, Cheung S-T, Leung S-F, Van Hasselt A, Tsang Y-S, Mak K-F, Chung Y-F, Woo JKS, Lee JCK and Huang DP (1996) Hypermethylation of the p16 gene in nasopharyngeal carcinoma. Cancer Res 56: 2721-2725
26. Maestro R, Gasparotto D, Vuksavljevic T, Barzan L, Sulfaro S and Boiocchi M (1993) Three discrete regions of deletion in head and neck cancers. Cancer Res 53: 5775-5779
27. Maniatis T, Fritsch EF and Sambrook J (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory: Cold Spring Harbor, NY
28. Meredith SD, Levine PA, Burns JA, Gaffey MJ, Boyd JC, Weiss LM, Erickson NL and Williams ME (1995) Chromosome 11q13 amplification in head and neck squamous cell carcinoma. Association with poor prognosis. Archives of Otolaryngology Head & Neck Surgery 121: 790-794
29. Mutirangura A, Greenberg F, Butler MG, Malcolm S, Nicholls RD, Chakravarti A and Ledbetter DH (1993) Multiplex PCR of three dinucleotide repeats in the Prader-Willi/Angelman critical region (15q11-q13): molecular diagnosis and mechanism of uniparental disomy. Hum Molec Genet 2: 143-151
30. Nawroz H, Van Der Riet P, Hruban RH, Koch W, Ruppert JM and Sidransky D (1994) Allelotype of head and neck squamous cell carcinoma. Cancer Res 54: 1152-1155
31. Rhyu MS (1996) Molecular mechanisms underlying hereditary nonpolyposis colorectal carcinoma. J Natl Cancer Inst 88: 240-251
32. Sample J, Young L, Martin B, Chatman T, Kieff E, Rickinson A and Kieff E (1990) Epstein-Barr virus type 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes. J Virol 64: 4084-4092
33. Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L, Tagle DA, Smith S, Uziel T, Sfez S, Ashkenazi M, Pecker I, Frydman M, Harnik R, Patanjali SR, Gatti RA, Chessa L, Sanal O, Lavin MF, Miki T, Weissman SM, Lovett M, Collin FS and Shiloh YA (1995) Single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749-1753
34. Shin DM, Kim J, Ro JY, Hittelman J, Roth JA, Hong WK and Hittelman WN (1994) Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 54: 321-326
35. Sun Y, Hegamyer G and Colburn NH (1993) Nasopharyngeal carcinoma shows no detectable retinoblastoma susceptibility gene alterations. Oncogene 8: 791-795
36. Thibodeau SN, Bren G and Schaid D (1993) Microsatellite instability in cancer of the proximal colon. Science 260: 816-819
37. Voravud N (1990) Cancer in the Far East. In Treatment of Cancer, 2nd edn, Sikora K and Halman KE. (eds) pp. 887-894. Chapman and Hall Medical: London
38. Young J, Leggett B, Ward M, Thomas L, Buttenshaw R, Searle J and Chenevix-Trench G (1993) Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas. Oncogene 8: 671-675
39. Zhu X, Dunn JM, Goddard AD, Squire JA, Becker A, Phillips RA and Gallie BL (1992) Mechanisms of loss of heterozygosity in retinoblastoma. Cytogenet Cell Genet 59: 248-252