메뉴 건너뛰기




Volumn 270, Issue 3 39-3, 1996, Pages

Impact of aging on adenosine levels, A1/A2 responses, arrhythmogenesis, and energy metabolism in rat heart

Author keywords

bradycardia; coronary vasculature; energy metabolism; phosphorus 31 nuclear magnetic resonance spectroscopy; senescence; vasodilation

Indexed keywords

8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CREATINE; CREATINE PHOSPHATE; OXYGEN;

EID: 0029961010     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.3.h897     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 0026100448 scopus 로고
    • Adenosine antagonism attenuates metabolic but not functional recovery from ischemia
    • (Heart Circ. Physiol. 29)
    • Angello, D. A., J. P. Headrick, N. M. Coddington, and R. M. Berne. Adenosine antagonism attenuates metabolic but not functional recovery from ischemia. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H193-H200, 1991.
    • (1991) Am. J. Physiol. , vol.260
    • Angello, D.A.1    Headrick, J.P.2    Coddington, N.M.3    Berne, R.M.4
  • 2
    • 0027991294 scopus 로고
    • Effects of aging on quantitative structural properties of coronary vasculature and microvasculature in rats
    • (Heart Circ. Physiol. 36)
    • Anversa, P., P. Li, E. H. Sonnenblick, and G. Olivetti. Effects of aging on quantitative structural properties of coronary vasculature and microvasculature in rats. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1062-H1073, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Anversa, P.1    Li, P.2    Sonnenblick, E.H.3    Olivetti, G.4
  • 3
    • 0019125074 scopus 로고
    • Atrioventricular conduction disturbances during hypoxia: Possible role of adenosine in rabbit and guinea pig heart
    • Belardinelli, L., F. L. Belloni, R. Rubio, and R. M. Berne. Atrioventricular conduction disturbances during hypoxia: possible role of adenosine in rabbit and guinea pig heart. Circ. Res. 47: 684-691, 1980.
    • (1980) Circ. Res. , vol.47 , pp. 684-691
    • Belardinelli, L.1    Belloni, F.L.2    Rubio, R.3    Berne, R.M.4
  • 5
    • 0019141614 scopus 로고
    • Role of adenosine in regulation of coronary blood flow
    • Berne, R. M. Role of adenosine in regulation of coronary blood flow. Circ. Res. 47: 807-813, 1980.
    • (1980) Circ. Res. , vol.47 , pp. 807-813
    • Berne, R.M.1
  • 6
    • 0023225087 scopus 로고
    • Maturation of coronary responsiveness to exogenous adenosine in the rabbit
    • Buss, D. D., W. W. Hennemann, and P. Posner. Maturation of coronary responsiveness to exogenous adenosine in the rabbit. Basic Res. Cardiol. 82: 290-296, 1987.
    • (1987) Basic Res. Cardiol. , vol.82 , pp. 290-296
    • Buss, D.D.1    Hennemann, W.W.2    Posner, P.3
  • 8
    • 0028899355 scopus 로고
    • Effects of age on intrinsic heart rate, heart rate variability, and AV conduction in healthy humans
    • (Heart Circ. Physiol. 37)
    • Craft, N., and J. B. Schwartz. Effects of age on intrinsic heart rate, heart rate variability, and AV conduction in healthy humans. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1441-H1452, 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Craft, N.1    Schwartz, J.B.2
  • 10
    • 0027164441 scopus 로고
    • Adenosine inhibition of β-adrenergic induced responses in aged hearts
    • (Heart Circ. Physiol. 34)
    • Dobson, J. G., Jr., and R. A. Fenton. Adenosine inhibition of β-adrenergic induced responses in aged hearts. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H494-H503, 1993.
    • (1993) Am. J. Physiol. , vol.265
    • Dobson Jr., J.G.1    Fenton, R.A.2
  • 11
    • 0025262387 scopus 로고
    • Increased myocardial adenosine production and reduction of β-adrenergic contractile response in aged hearts
    • Dobson, J. G., Jr., R. A. Fenton, and F. D. Romano. Increased myocardial adenosine production and reduction of β-adrenergic contractile response in aged hearts. Circ. Res. 66: 1381-1390, 1990.
    • (1990) Circ. Res. , vol.66 , pp. 1381-1390
    • Dobson Jr., J.G.1    Fenton, R.A.2    Romano, F.D.3
  • 12
    • 0022445502 scopus 로고
    • Endogenous adenosine inhibits catecholamine contractile responses in normoxic hearts
    • (Heart Circ. Physiol. 20)
    • Dobson, J. G., Jr., R. W. Ordway, and R. A. Fenton. Endogenous adenosine inhibits catecholamine contractile responses in normoxic hearts. Am. J. Physiol. 251 (Heart Circ. Physiol. 20): H455-H462, 1986.
    • (1986) Am. J. Physiol. , vol.251
    • Dobson Jr., J.G.1    Ordway, R.W.2    Fenton, R.A.3
  • 13
    • 0026533883 scopus 로고
    • Protective effects of adenosine in myocardial ischemia
    • Ely, S. W., and R. M. Berne. Protective effects of adenosine in myocardial ischemia. Circulation 85: 893-904, 1992.
    • (1992) Circulation , vol.85 , pp. 893-904
    • Ely, S.W.1    Berne, R.M.2
  • 14
    • 0020066862 scopus 로고
    • Cardiac arrhythmias in a healthy elderly population: Detection by 24-hour ambulatory electrocardiography
    • Fleg, J. L., and H. L. Kennedy. Cardiac arrhythmias in a healthy elderly population: detection by 24-hour ambulatory electrocardiography Chest 81: 302-307, 1982.
    • (1982) Chest , vol.81 , pp. 302-307
    • Fleg, J.L.1    Kennedy, H.L.2
  • 15
    • 0027136046 scopus 로고
    • Physiology of cardiovascular aging
    • Folkow, B., and A. Svanborg. Physiology of cardiovascular aging. Physiol. Rev. 73: 725-764, 1993.
    • (1993) Physiol. Rev. , vol.73 , pp. 725-764
    • Folkow, B.1    Svanborg, A.2
  • 16
    • 0025909934 scopus 로고
    • Adenosine deaminase and adenosine attenuate ventricular arryhthmias caused by norepinephrine
    • (Heart Circ. Physiol. 29)
    • Friedrichs, G. S., H. M. Wei, and G. F. Merrill. Adenosine deaminase and adenosine attenuate ventricular arryhthmias caused by norepinephrine. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H979-H984, 1991.
    • (1991) Am. J. Physiol. , vol.260
    • Friedrichs, G.S.1    Wei, H.M.2    Merrill, G.F.3
  • 17
    • 0025039441 scopus 로고
    • Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction: Mechanism and physiological implications
    • Froldi, G., and L. Belardinelli. Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction: mechanism and physiological implications. Circ. Res. 67: 960-978, 1990.
    • (1990) Circ. Res. , vol.67 , pp. 960-978
    • Froldi, G.1    Belardinelli, L.2
  • 19
    • 0018146030 scopus 로고
    • Age-related changes in the response of rabbit isolated aortae to vasoactive agents
    • Hayashi, S., and N. Toda. Age-related changes in the response of rabbit isolated aortae to vasoactive agents. Br. J. Pharmacol. 64: 229-237, 1978.
    • (1978) Br. J. Pharmacol. , vol.64 , pp. 229-237
    • Hayashi, S.1    Toda, N.2
  • 20
  • 21
    • 0027462303 scopus 로고
    • Myocardial adenosine, flow, and metabolism during adenosine antagonism and adrenergic stimulation
    • (Heart Circ. Physiol. 33)
    • Headrick, J. P., S. W. Ely, G. P. Matherne, and R. M. Berne. Myocardial adenosine, flow, and metabolism during adenosine antagonism and adrenergic stimulation. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H61-H70, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Headrick, J.P.1    Ely, S.W.2    Matherne, G.P.3    Berne, R.M.4
  • 22
    • 0023678640 scopus 로고
    • Mediation by adenosine of bradycardia in rat heart during graded global ischemia
    • Headrick, J., and R. J. Willis. Mediation by adenosine of bradycardia in rat heart during graded global ischemia. Pfluegers Arch. 412: 618-623, 1988.
    • (1988) Pfluegers Arch. , vol.412 , pp. 618-623
    • Headrick, J.1    Willis, R.J.2
  • 23
    • 0025344612 scopus 로고
    • 31P-NMR study in isolated rat heart
    • (Heart Circ. Physiol. 27)
    • 31P-NMR study in isolated rat heart. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H617-H624, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Headrick, J.1    Willis, R.J.2
  • 24
    • 0026673586 scopus 로고
    • Age related alterations in the response of the pial arterioles to adenosine in the rat
    • Jiang, H.-X., P. C-Y. Chen, S. S. Sobin, and S. L. Giannotta. Age related alterations in the response of the pial arterioles to adenosine in the rat. Mech. Ageing Dev. 65: 257-276, 1992.
    • (1992) Mech. Ageing Dev. , vol.65 , pp. 257-276
    • Jiang, H.-X.1    Chen, P.C.-Y.2    Sobin, S.S.3    Giannotta, S.L.4
  • 25
    • 0027417262 scopus 로고
    • Cardiovascular regulatory mechanisms in advanced age
    • Lakatta, E. G. Cardiovascular regulatory mechanisms in advanced age. Physiol. Rev. 73: 413-467, 1993.
    • (1993) Physiol. Rev. , vol.73 , pp. 413-467
    • Lakatta, E.G.1
  • 27
    • 0027229939 scopus 로고
    • Adenosine deaminase and BW A1433U attenuate hypoxia-induced ventricular ectopy
    • Leone, R. J., G. S. Friedrichs, and G. F. Merrill. Adenosine deaminase and BW A1433U attenuate hypoxia-induced ventricular ectopy. J. Appl. Physiol. 74: 1543-1548, 1993.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 1543-1548
    • Leone, R.J.1    Friedrichs, G.S.2    Merrill, G.F.3
  • 28
    • 0028985447 scopus 로고
    • 2b receptors in cultured fetal chick heart cells
    • 2b receptors in cultured fetal chick heart cells. Circ. Res. 76: 242-251, 1995
    • (1995) Circ. Res. , vol.76 , pp. 242-251
    • Liang, B.T.1    Haltiwanger, B.2
  • 30
    • 0025697171 scopus 로고
    • Ontogeny of the adenosine response in isolated guinea pig hearts and aorta
    • (Heart Circ. Physiol. 28)
    • Matherne, G. P., J. P. Headrick, and R. M. Berne. Ontogeny of the adenosine response in isolated guinea pig hearts and aorta. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1637-H1642, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Matherne, G.P.1    Headrick, J.P.2    Berne, R.M.3
  • 31
    • 0025334946 scopus 로고
    • Evidence for the involvement of cyclic GMP in adenosine-induced, age-dependent vasodilatation
    • Moritoki, H., T. Matsugi, H. Takase, H. Ueda, and A. Tanioka. Evidence for the involvement of cyclic GMP in adenosine-induced, age-dependent vasodilatation. Br. J. Pharmacol. 100: 569-575, 1990.
    • (1990) Br. J. Pharmacol. , vol.100 , pp. 569-575
    • Moritoki, H.1    Matsugi, T.2    Takase, H.3    Ueda, H.4    Tanioka, A.5
  • 32
    • 0025326815 scopus 로고
    • Cardiovascular purinoceptors
    • Olsson, R. A., and J. D. Pearson. Cardiovascular purinoceptors. Physiol. Rev. 70: 761-845, 1990.
    • (1990) Physiol. Rev. , vol.70 , pp. 761-845
    • Olsson, R.A.1    Pearson, J.D.2
  • 33
    • 0023933154 scopus 로고
    • Expansion of extracellular tracer spaces in the isolated heart perfused with crystalloid solutions: Expansion of extracellular space, transsarcolemmal leakage, or both?
    • Polimeni, P. I., and S. I. Buraczewski. Expansion of extracellular tracer spaces in the isolated heart perfused with crystalloid solutions: expansion of extracellular space, transsarcolemmal leakage, or both? J. Mol. Cell. Cardiol. 20: 15-22, 1988.
    • (1988) J. Mol. Cell. Cardiol. , vol.20 , pp. 15-22
    • Polimeni, P.I.1    Buraczewski, S.I.2
  • 34
    • 0025648337 scopus 로고
    • Adenosine modulates β-adrenergic signal transduction in guinea-pig heart ventricular membranes
    • Romano, F. D., and J. G. Dobson, Jr. Adenosine modulates β-adrenergic signal transduction in guinea-pig heart ventricular membranes. J. Mol. Cell. Cardiol. 22: 1359-1370, 1990.
    • (1990) J. Mol. Cell. Cardiol. , vol.22 , pp. 1359-1370
    • Romano, F.D.1    Dobson Jr., J.G.2
  • 35
    • 0026563271 scopus 로고
    • Effects of physiological aging on cardiac electrophysiology in perfused Fischer 344 rat hearts
    • (Heart Circ. Physiol. 31)
    • Sehmidlin, O., S. Bharati, M. Lev, and J. B. Schwartz. Effects of physiological aging on cardiac electrophysiology in perfused Fischer 344 rat hearts. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H97-H105, 1992.
    • (1992) Am. J. Physiol. , vol.262
    • Sehmidlin, O.1    Bharati, S.2    Lev, M.3    Schwartz, J.B.4
  • 36
    • 0025991263 scopus 로고
    • Delineation of the effects of moderate aging on myocardial perfusion
    • Senneff, M. J., E. M. Geltmann, S. R. Bergmann, and J. Hartmen. Delineation of the effects of moderate aging on myocardial perfusion. J. Nucl. Med. 32. 2037-2042, 1991.
    • (1991) J. Nucl. Med. , vol.32 , pp. 2037-2042
    • Senneff, M.J.1    Geltmann, E.M.2    Bergmann, S.R.3    Hartmen, J.4
  • 37
    • 0027338414 scopus 로고
    • 2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cyclic AMP accumulation in guinea pig, rat, or rabbit isolated ventricular myocytes
    • 2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cyclic AMP accumulation in guinea pig, rat, or rabbit isolated ventricular myocytes. Circ. Res. 72: 194-205, 1993.
    • (1993) Circ. Res. , vol.72 , pp. 194-205
    • Shyrock, J.1    Song, Y.2    Wang, D.3    Baker, S.P.4    Olsson, R.A.5    Belardinelli, L.6
  • 38
    • 0022343258 scopus 로고
    • Effect of development on coronary vasodilator reserve in the isolated guinea pig heart
    • Toma, B. S., R. D. Wangler, D. F. Dewitt, and H. V. Sparks. Effect of development on coronary vasodilator reserve in the isolated guinea pig heart. Circ. Res. 57: 538-544, 1985.
    • (1985) Circ. Res. , vol.57 , pp. 538-544
    • Toma, B.S.1    Wangler, R.D.2    Dewitt, D.F.3    Sparks, H.V.4
  • 39
    • 0026633844 scopus 로고
    • Cardiac microdialysis in isolated rat hearts: Interstitial purine metabolites during ischemia
    • (Heart Circ. Physiol. 31)
    • Van Wylen, D. G., T. J. Schmit, R. D. Lasley, R. L. Gingell, and R. M. Mentzer, Jr. Cardiac microdialysis in isolated rat hearts: interstitial purine metabolites during ischemia. Am. J Physiol. 262 (Heart Circ. Physiol. 31): H1934-H1938, 1992.
    • (1992) Am. J Physiol. , vol.262
    • Van Wylen, D.G.1    Schmit, T.J.2    Lasley, R.D.3    Gingell, R.L.4    Mentzer Jr., R.M.5
  • 40
    • 0021911670 scopus 로고
    • Sick sinus syndrome: An adenosine-mediated disease
    • Watt, A. H. Sick sinus syndrome: an adenosine-mediated disease. Lancet 1: 786-788, 1985.
    • (1985) Lancet , vol.1 , pp. 786-788
    • Watt, A.H.1
  • 41
    • 13344265603 scopus 로고
    • Expression and pharmacological characterization of a stimulatory subtype of adenosine receptor in ventricular myocyte
    • Xu, D., H. Kong, and B. T. Liang. Expression and pharmacological characterization of a stimulatory subtype of adenosine receptor in ventricular myocyte. Circ. Res. 70: 55-56, 1992.
    • (1992) Circ. Res. , vol.70 , pp. 55-56
    • Xu, D.1    Kong, H.2    Liang, B.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.