Age-related decline in beta adrenergic and adenosine A1 receptor function in the heart are attenuated by dietary restriction

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 1, 1998, Pages 186-192

  Gao, Erhe ^a   Snyder, David L ^a   Roberts, Jay ^a   Friedman, Eitan ^a   Cai, Guoping ^a   Pelleg, Amir ^a   Horwitz, Joel ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A1 RECEPTOR; BETA ADRENERGIC RECEPTOR;

AGING; ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIC INTAKE; DIET RESTRICTION; HEART FUNCTION; PRIORITY JOURNAL; RECEPTOR BINDING;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; AGE FACTORS; ANIMALS; CYCLIC AMP; DIET; FORSKOLIN; GTP-BINDING PROTEINS; HEART; ISOPROTERENOL; MALE; MYOCARDIUM; RATS; RATS, INBRED F344; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, PURINERGIC P1;

EID: 0031956231     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Abrass IB, Davis JL and Scarpace PJ (1982) Isoproterenol responsiveness and myocardial β-adrenergic receptors in young and old rats. J Gerontol 37:156-160.
2. Achterberg PW, de Tombe P, Harness E and de Jong JW (1985) Myocardial S-adenosyl-homocysteine hydrolase is important for adenosine production during normoxia. Biochim Biophys Acta 840:393-400.
3. Belardmelli L and Isenberg G (1983) Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res 53:287-297.
4. Benedetti A, Ferreti G, Curatola G, Jezequel AM and Orlandi F (1988) Age and sex related changes of plasma membrane fluidity in isolated rat hepatocytes. Biochem Biophys Res Commun 156:840-845.
5. Birnbaumer L, Codina J, Matters R, Cerione RA, Hildbrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkovitz RJ and Iyengar R (1985) Regulation of hormone receptors and adenylyl cyclase by guanine nucleotide N protein. Recent Prog Horm Res 41:41-99.
6. Bradford MM (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72:248-254.
7. 3H]NECA in rat striatal membranes. Mol. Pharmacol 29:331-346.
8. 1 receptor-Gα protein coupling in rat cardiac ventricles during aging. Circ Res 81:1065-1071.
9. 1-adrenergic receptors and G-protein in the rat parotid gland. J Gerontol Biol Sci 52A:B103-B110.
10. Dax EM, Ingram DK, Partilla JS and Gregerman RI (1989) Food restriction prevents an age-associated increase in rat liver beta-adrenergic receptors. J Gerontol Biol Sci 44:B72-B76.
11. Dobson JG Jr, Fenton RA and Romano FD (1990) Increased myocardial adenosine production and reduction of β-adrenergic contractile response in aged hearts. Circ Res 66:1381-1390.
12. Evans DB and Sehenden JA (1982) Adenosine receptors mediating cardiac depression. Life Sci 31:2425-2432.
13. 1 receptor function in the rat heart. J Mol Cell. Cardiol 29:593-602.
14. 1-adrenoceptor mediated responses during aging in Fischer 344 rats. J Gerontol Biol Sci 50A:B67-B71.
15. 1adenosine receptors on ventricular cardiomyocytes from adult rat and dog heart. Life Sci 41:2381-2388.
16. Herlihy JT (1984) Dietary manipulation of cardiac and aortic smooth muscle reactivity to isoproterenol. Am J Physiol 246:H369-H373.
17. Herlihy JT and Kim S-W (1994) Modulation of the aging cardiovascular system by dietary restriction, in Modulation of Aging Processes by Dietary Restriction (Yu BP, ed) pp 57-87, CRC Press, Boca Raton, FL.
18. Huang M and Drummond GI (1976) Effect of adenosine on cyclic AMP accumulation in ventricular myocardium. Biochem J 25:2713-2719.
19. Insel PA (1993) Adrenergic receptors, G proteins, and cell regulation: implications for aging research. Exp Gerontol 28:341-348.
20. Itoh H, Kozasa T, Nagata S, Nakaminuura S, Katada T, Ui M, Iwai S, Ohtsuka E, Kawasaki H, Suzuki K and Kaziro Y (1986) Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide binding proteins Gs, Gi and Go from rat brain. Proc Natl Acad Sci USA 83:3776-3780.
21. 6-sulfoalkyl derivatives of adenosine: water soluble and peripherally selective adenosine agonists. J Med Chem 35:4143-4149.
22. Johnson MD, Zhou Y, Friedman E and Roberts J (1995) Expression of G protein α subunits in the aging cardiovascular system. J Gerontol 50A:B14-B19.
23. Jones DTR and Reed RR (1987) Molecular cloning of five GTP binding protein cDNA species from rat olfactory neuroepithelium. J Biol Chem 262:9239-9245.
24. Katz MS (1988) Food restriction modulates β-adrenergic-sensitive adenylate cyclase in rat liver during aging. Am J Physiol 254:E54-E62.
25. Kobayashi I, Shibasaki H, Takahashi K, Toyama K, Kurachi Y, Ito H, Ui M and Katada T (1990) Purification and characterization of five different subunits of guanine nucleotide binding proteins in bovine brain membranes. Eur J Biochem 191:499-506.
26. Lee HT, Thompson CL, Linden J and Belloni FL (1993) Differential sensitization of cardiac actions of adenosine in rat after chronic theophylline treatment. Am J Physiol 264:H1634-H1643.
27. Linden J, Hollen CE and Patel A (1985) The mechanism by which adenosine and cholinergic agents reduce contractility in rat myocardium. Circ Res 56:728-735.
28. 1 adenosine receptors in isolated rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol 336:342-348.
29. Masoro EJ (1993) Dietary restriction and aging. J Am Geriatr Sac 41:994-999.
30. 1 receptor activation: Direct effects on chronotropic and inotropic function in the Fisher 344 rat. J Gerontol 51A:B239-B246.
31. Narayanan N and Derby JA (1982) Alterations in the properties of β-adrenergic receptors of myocardial membranes in aging: impairments in agonist-receptor interactions and guanine nucleotide regulation accompany diminished catecholamine-responsiveness of adenylate cyclase. Mech Ageing Dev 19:127-139.
32. O'Connor SW, Scarpace PJ and Abrass IB (1981) Age-associated decrease of adenylate cyclase activity in rat myocardium. Mech Ageing Dev 16:91-95.
33. O'Connor SW, Scarpace PJ and Abrass IB (1983) Age-associated decrease in the catalytic unit activity of rat myocardial adenylate cyclase. Mech Aging Dev 21: 357-363.
34. Romano FD, Naimi TS and Dobson Jr JR (1991) Adenosine attenuation of catecholamine-enhanced contractility of rat heart in vivo. Am J Physiol. 260:H1635-H1639.
35. Romano FD and Dobson Jr JG (1996) Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart. Life Sci 58:493-502.
36. Salomon Y (1979) Adenylate cyclase assay, in Advances in Cyclic Nucleotide Research (Brooker G, Greengard P and Robison GA, eds) vol 10, pp 35-55, Raven Press, New York.
37. Scarpace PJ (1990) Forskolin activation of adenylate cyclase in rat myocardium with age: effect of guanine nucleotide analogs. Mech Ageing Dev 52:169-178.
38. Scarpace PJ and Abrass IB (1986) Beta-adrenergic agonist-mediated desensitization in senescent rats. Mech Ageing Dev 35:255-264.
39. Scarpace PJ and Yu BP (1987) Diet restriction retards the age-related loss of beta-adrenergic receptors and adenylate cyclase activity in rat lung. J Gerontol 42:442-446.
40. Seamon KB and Daly JW (1986) Forskolin: Its biological and chemical properties Adv Cyclic Nucleotide Protein Phosphorylation Res 20:1-150.
41. Shamin MT, Ukena D, Padgett WL and Daly JW (1989) Effect of 8-phenyl and 8-cycloalkyl substitutes on the activity of mono-, di, and trisubstituted alkylxanthines and substitution at the 1-, 3-, and 7-positions. J Med Chem 32:1231-1237.
42. Shu Y and Scarpace PJ (1994) Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging. J Cardiovasc Pharmacol 23:188-193.
43. Snyder DL, Wostmann BS, Pollard M, Luckert PH (1990) The survival, pathology and morphology of diet-restricted conventional and germ-free Lobund-Wistar rats J Gerontol Biol Sci 45:B52-B58.
44. Sparks HV and Bardenhauer H (1986) Regulation of adenosine formation in the heart. Circ Res 58:193-201.
45. Viani P, Cervato G, Fiorilli A and Cestaro A (1991) Age-related differences in synaptosomal peroxidative damage an membrane properties. J Neurochem 56: 253-258.
46. Yu BP (1994) How diet influences the aging process of the rat. Proc Soc Exp Biol Med 205:97-105.