Structure-activity relationships of 3-deoxy androgens as aromatase inhibitors. synthesis and biochemical studies of 4-substituted 4-ene and 5-ene steroids

Steroids

Volumn 68, Issue 6, 2003, Pages 533-542

  Nagaoka, Masao ^a   Watari, Yoko ^a   Yajima, Hiromi ^a   Tsukioka, Kaoru ^a   Muroi, Yasuyo ^a   Yamada, Keiko ^a   Numazawa, Mitsuteru ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

3 Deoxy androgen; 4 Acyloxy steroid; 4 Alkyl steroid; Aromatase; Human placental microsomes; Inhibitor

Indexed keywords

4 ACETATE ANDROST 4 EN 17 ONE; 4 ACETOXY 19 OL ANDROST 4 EN 17 ONE; 4 BENZOATE ANDROST 4 EN 17 ONE; 4 BETA (4' METHOXY)BENZYLANDROST 5 EN 17 ONE; 4 BETA BENZYLANDROST 5 EN 17 ONE; 4 BETA ETHOXYANDROST 5 EN 17 ONE; 4 BETA METHOXYANDROST 5 EN 17 ONE; 4 BETA METHYLANDROST 5 EN 17 ONE; 4 BETA N PROLYLANDROST 5 EN 17 ONE; 4 N BUTYLATE ANDROST 4 EN 17 ONE; 4 N HEXANOATE ANDROST 4 EN 17 ONE; ANDROGEN; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMISTRY; COLUMN CHROMATOGRAPHY; CRYSTALLIZATION; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 0042167222     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(03)00085-0     Document Type: Article

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