Aromatization of 16α-hydroxyandrostenedione by human placental microsomes: Effect of preincubation with suicide substrates of androstenedione aromatization

Journal of Steroid Biochemistry and Molecular Biology

Volumn 81, Issue 2, 2002, Pages 165-172

  Numazawa, Mitsuteru ^a   Tachibana, Mii ^a   Mutsumi, Ayako ^a   Yoshimura, Akiko ^a   Osawa, Yoshio ^b  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

16 Hydroxyandrostenedione; Aromatase; Aromatization; Human placental microsome; Suicide substrate; Time dependent inactivation

Indexed keywords

10BETA ACETOXYESTR 5 ENE 7,17 DIONE; 16ALPHA HYDROXYANDROSTENEDIONE; 6 OXOANDROSTENEDIONE; ANDROST 5 ENE 4,7,17 TRIONE; ANDROSTENEDIONE; ANDROSTENEDIONE DERIVATIVE; AROMATASE; ESTRIOL; ESTRONE; FORMESTANE; NORETHISTERONE; SUICIDE SUBSTRATE; TRITIUM; UNCLASSIFIED DRUG; WATER; 16 HYDROXYANDROST 4 EN 3,17 DIONE; 16-HYDROXYANDROST-4-EN-3,17-DIONE; DRUG DERIVATIVE;

AROMATIZATION; ARTICLE; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GAS CHROMATOGRAPHY; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MICROSOME; PLACENTA; ENZYMOLOGY; FEMALE; METABOLISM; PREGNANCY;

TRITIUM;

ANDROSTENEDIONE; AROMATASE; FEMALE; HUMANS; MICROSOMES; PLACENTA; PREGNANCY;

EID: 0035984318     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(02)00060-2     Document Type: Article

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