Characterization of antisense oligonucleotide-peptide conjugates with negative ionization electrospray mass spectrometry and liquid chromatography-mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 32, Issue 4-5, 2003, Pages 581-590

  Tengvall, Unni ^a   Auriola, Seppo ^a   Antopolsky, Maxim ^a   Azhayev, Alex ^a   Biegelman, Leo ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Sirna Therapeutics Inc   (United States)

Author keywords

Antisense oligonucleotides; LC MS; MS; Oligonucleotide peptide conjugates

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; HYBRID PROTEIN; PEPTIDE; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBOZYME;

CHEMICAL MODIFICATION; CONFERENCE PAPER; CONJUGATE; DRUG CONJUGATION; ERROR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL;

EID: 0042124980     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00165-1     Document Type: Conference Paper

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