Template-directed ligation of peptides to oligonucleotides

Chemistry and Biology

Volumn 3, Issue 1, 1996, Pages 49-56

  Bruick, Richard K ^a   Dawson, Philip E ^a   Kent, Stephen B H ^a   Usman, Nassim ^b   Joyce, Gerald F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Sirna Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; OLIGONUCLEOTIDE; PEPTIDE;

ARTICLE; CHEMISTRY; DNA TEMPLATE; MASS SPECTROMETRY; NASA DISCIPLINE EXOBIOLOGY; NON-NASA CENTER;

NASA DISCIPLINE EXOBIOLOGY; NON-NASA CENTER;

AMIDES; MASS SPECTROMETRY; OLIGONUCLEOTIDES; PEPTIDES; TEMPLATES, GENETIC;

EID: 0030019353     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(96)90084-8     Document Type: Article

References (11)

1. 4-poly(L-lysine) conjugates in intact cells. Biochemistry 25, 3730-3736.
2. Lemaitre, M., Bayard, B. & Lebleu, B. (1987). Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site. Proc. Natl. Acad Sci. USA 84, 648-652.
3. Leonetti, J., Degols, G. & Lebleu, B. (1990). Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake. Bioconjugate Chem. 1, 149-153.
4. Zhu, T., et al., & Stein, S. (1993). Oligonucleotide-poly-L-ornithine conjugates: binding to complementary DNA and RNA. Antisense Res. Dev. 3, 265-275.
5. Levy, H.B., et al., & Rice, J. (1975). A modified polyriboinosinic-polyribocytidylic acid complex that induces interferon in primates. J. Infect. Dis. 132, 434-439.
6. Corey, D.R. (1995). 48 000-fold acceleration of hybridization by chemically modified oligonucleotides. J. Am. Chem. Soc. 117, 9373-9374.
7. Arar, K., Aubertin, A., Roche, A., Monsigny, M. & Mayer, R. (1995). Synthesis and antiviral activity of peptide-oligonucleotide conjugates prepared by using Nα-(bromoacetyl)peptides. Bioconjugate Chem. 6, 573-577.
8. Jablonski, E., Moomaw, E.W., Tullis, R.H. & Ruth, J.L. (1986). Preparation of oligonucleotide-alkaline phosphatase conjugates and their use as hybridization probes. Nucleic Acids Res. 14, 6115-6128.
9. Li, P., Medon, P.P., Skingle, D.C., Lanser, J.A. & Symons, R.H. (1987), Enzyme-linked synthetic oligonucleotide probes: non-radioactive detection of enterotoxigenic Escherichia coli in faecal specimens. Nucleic Acids Res. 15, 5275-5287.
10. Chu, B.C.F. & Orgel, L.E. (1988). Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds. Nucleic Acids Res. 16, 3671-3691.
11. Haralambidis, J., et al., & Tregear, G.W. (1990). The preparation of polyamide-oligonucleotide probes containing multiple non-radioactive labels. Nucleic Acids Res. 18, 501-505.