Acute uremia produced in rats by nephrotoxic chemicals is alleviated by protein deficient diet

Renal Failure

Volumn 25, Issue 4, 2003, Pages 517-523

  Levine, Seymour ^a   Saltzman, Arthur ^a  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

D Serine, Metallothionein; Mercuric chloride; Nephrotoxin; Nutrition; Protein deficiency; Uremia

Indexed keywords

DEXTRO SERINE; MERCURIC CHLORIDE; METALLOTHIONEIN;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; MALE; MORTALITY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN RESTRICTION; RAT; RAT STRAIN; SERUM; TREMOR; UREMIA;

ACUTE DISEASE; ANIMALS; BIOLOGICAL MARKERS; BODY WEIGHT; DIET, PROTEIN-RESTRICTED; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, SUBCUTANEOUS; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; MALE; MERCURIC CHLORIDE; METALLOTHIONEIN; PHOSPHATES; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; SUCROSE; TIME FACTORS; TREATMENT OUTCOME; UREA; UREMIA;

EID: 0042122743     PISSN: 0886022X     EISSN: None     Source Type: Journal    
DOI: 10.1081/JDI-120022542     Document Type: Article

References (22)

1. Gretz, N.; Strauch, M., Eds. Experimental and Genetic Rat Models of Chronic Renal Failure; Karger: Basel, 1993.
2. Gretz, N.; Strauch, M., Eds. Animal models in chronic renal failure. Contributions to Nephrology 1988, 60, 1-263.
3. Tanner, G.A. Experimental models of acute tubular necrosis. In Handbook of Animal Models of Renal Failure; Ash, S.R., Thornhill, J.A., Eds.; CRC Press: Boca Raton, 1985; 109-144.
4. Levine, S.; Saltzman, A. Carbohydrate diet prolongs survival of rats with acute uremia after bilateral nephrectomy. Nephron 1997, 77, 242-243.
5. Levine, S.; Saltzman, A. Prolongation of survival after bilateral ureteral ligation in rats. Nephron 2000, 84, 383-384.
6. Shea, S.M. The method of paired comparisons in histopathological ranking. A.M.A. Arch. Pathol. 1958, 65, 77-80.
7. Boitnott, J.N.; Solez, K. The use of ranking in the statistical assessment of morphologic data. In Acute Renal Failure. Correlation Between Morphology and Function; Solez, K., Whelton, A., Eds.; Marcel Dekker, Inc.: New York, 1984, 13-16.
8. Onosaka, S.; Cherian, M.G. The induced synthesis of metallothionein in various tissues of rats in response to metals. II. Influence of zinc status and specific effect on pancreatic metallothionein. Toxicology 1982, 23, 11-20.
9. Holck, H.G.O. Dosage of drugs for rats. In The Rat in Laboratory Investigation; Farris, E.J., Griffith, J.Q., Eds.; Hafner Publishing Co.: New York, 1949.
10. Kato, R.; Oshima, T.; Tomizawa, S. Toxicity and metabolism of drugs in relation to dietary protein. Jap. J. Pharmacol. 1968, 18, 356-366.
11. Brenner, B.M.; Meyer, T.W.; Hostetter, T.H. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N. Engl. J. Med. 1982, 307, 652-659.
12. Maroni, B.J.; Mitch, W.E. Role of nutrition in prevention of the progression of renal disease. Ann. Rev. Nut. 1997, 17, 435-455.
13. Niwa, T.; Ise, M. Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis. J. Lab. Clin. Med. 1994, 124, 96-104.
14. Motojima, M.; Hosokawa, A.; Yamato, H.; Muraki, T.; Yoshioka, T. Uremic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake. Brit. J. Pharmacol. 2002, 135, 555-563.
15. Zalups, R. Molecular interactions with mercury in the kidney. Pharmacol. Rev. 2000, 52, 113-143.
16. Chapman, L.; Chan, H.M. The influence of nutrition on methyl mercury intoxication. Environmental Health Perspectives 2000, 108 (suppl. 1), 29-56.
17. Adachi, T.; Yasutake, A.; Eto, K.; Hirayama, K. Influence of dietary protein levels on the acute toxicity of methylmercury in mice. Toxicology 1996, 112, 11-17.
18. Hostetter, T.H.; Meyer, T.W.; Rennke, H.G.; Brenner, B.M. Chronic effects of dietary protein in the rat with intact and reduced renal mass. Kidney Int. 1986, 30, 509-517.
19. Kenner, C.H.; Evan, A.P.; Blomgren, P.; Aronoff, G.R.; Luft, F.C. Effect of protein intake on renal function and structure in partially nephrectomized rats. Kidney Int. 1985, 27, 739-750.
20. Kleinknecht, C.; Salusky, I.; Broyer, M.; Gubler, M.-C. Effect of various protein diets on growth, renal function and survival of uremic rats. Kidney Int. 1979, 15, 534-541.
21. Bremner, I. Cadmium toxicity. Nutritional influences and the role of metallothionein. World Rev. Nutrition Diet 1978, 32, 165-197.
22. Shaikh, Z.A.; Jordan, S.A.; Tang, W. Protection against chronic cadmium toxicity by caloric restriction. Toxicology 1999, 133, 93-103.