Direct synthesis of 1,1′-[1,4-phenylenebis(methylene)]-bis-1,4,8,11- tetraazacyclotetradecane octahydrochloride (AMD 3100) without the use of protecting groups

Journal of Organic Chemistry

Volumn 68, Issue 16, 2003, Pages 6435-6436

  Achmatowicz, Michal ^a   Hegedus, Louis S ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COUPLING REACTIONS;

REACTION KINETICS; SYNTHESIS (CHEMICAL);

ORGANIC COMPOUNDS;

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ACRYLIC ACID METHYL ESTER; CYCLAM DERIVATIVE; ETHYLENEDIAMINE; MALONIC ACID DERIVATIVE; MALONIC ACID DIMETHYL ESTER; PARA XYLENE; TRIOXOCYCLAM; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTALLIZATION; DRUG SYNTHESIS; FILTRATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFRARED SPECTROSCOPY; MICHAEL ADDITION; PRECIPITATION; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION;

ACRYLATES; ANTI-HIV AGENTS; ETHYLENEDIAMINES; HETEROCYCLIC COMPOUNDS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0042074662     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo030146r     Document Type: Article

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