메뉴 건너뛰기




Volumn 77, Issue 17, 2003, Pages 9422-9430

Variability at human immunodeficiency virus type 1 subtype C protease cleavage sites: An indication of viral fitness?

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; NEF PROTEIN; POL PROTEIN; PROTEINASE;

EID: 0041888278     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.17.9422-9430.2003     Document Type: Article
Times cited : (54)

References (49)
  • 1
    • 0034897709 scopus 로고    scopus 로고
    • Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution
    • Anisimova, M., J. P. Bielawski, and Z. Yang. 2001. Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution. Mol. Biol. Evol. 18:1585-1592.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 1585-1592
    • Anisimova, M.1    Bielawski, J.P.2    Yang, Z.3
  • 3
    • 0024238272 scopus 로고
    • Synthetic peptides as substrates and inhibitors of human immunodeficiency virus-1 protease
    • Billich, S., M. T. Knoop, J. Hansen, P. Strop, J. Sedlacek, R. Mertz, and K. Moelling. 1988. Synthetic peptides as substrates and inhibitors of human immunodeficiency virus-1 protease. J. Biol. Chem. 263:17905-17908.
    • (1988) J. Biol. Chem. , vol.263 , pp. 17905-17908
    • Billich, S.1    Knoop, M.T.2    Hansen, J.3    Strop, P.4    Sedlacek, J.5    Mertz, R.6    Moelling, K.7
  • 5
    • 0035163687 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir
    • Cote, H. C. F., Z. L. Brumme, and P. R. Harrigan. 2001. Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir. J. Virol. 75:589-594.
    • (2001) J. Virol. , vol.75 , pp. 589-594
    • Cote, H.C.F.1    Brumme, Z.L.2    Harrigan, P.R.3
  • 6
    • 0031015475 scopus 로고    scopus 로고
    • Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors
    • Croteau, G., L. Doyon, D. Thibeault, G. McKercher, L. Pilote, and D. Lamarre. 1997. Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors. J. Virol. 71:1089-1096.
    • (1997) J. Virol. , vol.71 , pp. 1089-1096
    • Croteau, G.1    Doyon, L.2    Thibeault, D.3    McKercher, G.4    Pilote, L.5    Lamarre, D.6
  • 7
    • 0042463364 scopus 로고    scopus 로고
    • An integrated Genetic Data Environment (GDE)-based LINUX interface for the analysis of HIV-1 and other microbial sequences
    • De Oliveira, T., R. Miller, M. Tarin, and S. Cassol. 2002. An integrated Genetic Data Environment (GDE)-based LINUX interface for the analysis of HIV-1 and other microbial sequences. Bioinformatics 19:1-2.
    • (2002) Bioinformatics , vol.19 , pp. 1-2
    • De Oliveira, T.1    Miller, R.2    Tarin, M.3    Cassol, S.4
  • 8
    • 0029899093 scopus 로고    scopus 로고
    • Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors
    • Doyon, L., G. Croteau, D. Thibeault, F. Poulin, L. Pilote, and D. Lamarre. 1996. Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors. J. Virol. 70:3736-3769.
    • (1996) J. Virol. , vol.70 , pp. 3736-3769
    • Doyon, L.1    Croteau, G.2    Thibeault, D.3    Poulin, F.4    Pilote, L.5    Lamarre, D.6
  • 10
    • 0034631503 scopus 로고    scopus 로고
    • Accelerating the development and future availability of HIV-1 vaccines: Why, when, where and how?
    • Esparza, J., and N. Bhamarapravati. 2000. Accelerating the development and future availability of HIV-1 vaccines: why, when, where and how? Lancet 355:2061-2066.
    • (2000) Lancet , vol.355 , pp. 2061-2066
    • Esparza, J.1    Bhamarapravati, N.2
  • 12
    • 0042964538 scopus 로고    scopus 로고
    • The subtype C of human immunodeficiency virus type 1 circulating in Brazil and South Africa presents a hypersusceptibility to the protease inhibitor Lopinavir
    • in press
    • Gonzales, L. J. M., R. M. Brindeiro, M. Gordon, A. Calazans, M. A. Soares, S. Cassol, and A. Tanuri. The subtype C of human immunodeficiency virus type 1 circulating in Brazil and South Africa presents a hypersusceptibility to the protease inhibitor Lopinavir. J. Antimicrob. Chemother. in press.
    • J. Antimicrob. Chemother.
    • Gonzales, L.J.M.1    Brindeiro, R.M.2    Gordon, M.3    Calazans, A.4    Soares, M.A.5    Cassol, S.6    Tanuri, A.7
  • 13
    • 0037320125 scopus 로고    scopus 로고
    • Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa: Implications for vaccine and antiretroviral control strategies
    • Gordon, M., T. De Oliveira, K. Bishop, H. M. Coovadia, L. Madurai, S. Engelbrecht, E. Janse van Rensburg, A. Mosam, and S. Cassol. 2003. Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa: implications for vaccine and antiretroviral control strategies. J. Virol. 77:2587-2599.
    • (2003) J. Virol. , vol.77 , pp. 2587-2599
    • Gordon, M.1    De Oliveira, T.2    Bishop, K.3    Coovadia, H.M.4    Madurai, L.5    Engelbrecht, S.6    Van Rensburg, E.J.7    Mosam, A.8    Cassol, S.9
  • 14
    • 0034444948 scopus 로고    scopus 로고
    • Positive and negative aspects of the human immunodeficiency virus protease: Development of inhibitors versus its role in AIDS pathogenesis
    • Ikuta, K., S. Suzuki, H. Horikoshi, T. Mukai, and R. B. Luftig. 2000. Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesis. Microbiol. Mol. Biol. Rev. 64:725-745.
    • (2000) Microbiol. Mol. Biol. Rev. , vol.64 , pp. 725-745
    • Ikuta, K.1    Suzuki, S.2    Horikoshi, H.3    Mukai, T.4    Luftig, R.B.5
  • 15
    • 0023870815 scopus 로고    scopus 로고
    • Characterization of ribosomal frameshifting in HIV-1 gag-pol expression
    • Jacks, T., M. D. Power, F. R. Masiarz, P. A. Luciw, P. J. Barr, H. E. Varmus. 1998. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Nature 331:280-283.
    • (1998) Nature , vol.331 , pp. 280-283
    • Jacks, T.1    Power, M.D.2    Masiarz, F.R.3    Luciw, P.A.4    Barr, P.J.5    Varmus, H.E.6
  • 16
    • 0027932364 scopus 로고
    • The activity of the protease of HIV-1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency
    • Kaplan, A. H., M. Manchester, and R. Swanstrom. 1994. The activity of the protease of HIV-1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency. J. Virol. 68:6782-6786.
    • (1994) J. Virol. , vol.68 , pp. 6782-6786
    • Kaplan, A.H.1    Manchester, M.2    Swanstrom, R.3
  • 17
    • 1542502945 scopus 로고
    • Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides
    • Krausslich, H., F. H. Ingraham, M. Skoog, E. Wimmer, P. V. Pallai, and C. A. Carter. 1989. Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides. Proc. Natl. Acad. Sci. USA 86:807-811.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 807-811
    • Krausslich, H.1    Ingraham, F.H.2    Skoog, M.3    Wimmer, E.4    Pallai, P.V.5    Carter, C.A.6
  • 19
    • 0034059812 scopus 로고    scopus 로고
    • Transmission and prevalence of HIV resistance among treatment-naïve subjects
    • Little, S. J. 2000. Transmission and prevalence of HIV resistance among treatment-naïve subjects. Antivir. Ther. 5:33-40.
    • (2000) Antivir. Ther. , vol.5 , pp. 33-40
    • Little, S.J.1
  • 20
    • 0034691653 scopus 로고    scopus 로고
    • Comparisons of Vpu sequences from diverse geographical isolates of HIV type 1 identifies the presence of highly variable domains, additional invariant amino acids and a signature sequence motif common to subtype C isolates
    • McCormick-Davis, C., S. B. Dalton, D. K. Singh, and E. B. Stephens. 2000. Comparisons of Vpu sequences from diverse geographical isolates of HIV type 1 identifies the presence of highly variable domains, additional invariant amino acids and a signature sequence motif common to subtype C isolates. AIDS Res. Hum. Retrovir. 16:1089-1095.
    • (2000) AIDS Res. Hum. Retrovir. , vol.16 , pp. 1089-1095
    • McCormick-Davis, C.1    Dalton, S.B.2    Singh, D.K.3    Stephens, E.B.4
  • 21
    • 0036145336 scopus 로고    scopus 로고
    • The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles
    • Muller, B., T. Patschinsky, and H. G. Krausslich. 2002. The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles. J. Virol. 76:1015-1024.
    • (2002) J. Virol. , vol.76 , pp. 1015-1024
    • Muller, B.1    Patschinsky, T.2    Krausslich, H.G.3
  • 24
    • 0037213627 scopus 로고    scopus 로고
    • The dimer interfaces of protease and extra-protease domains influence the activation of protease and the specificity of GagPol cleavage
    • Pettit, S. C., S. Gulnik, L. Everitt, and A. H. Kaplan. 2003. The dimer interfaces of protease and extra-protease domains influence the activation of protease and the specificity of GagPol cleavage. J. Virol. 77:366-374.
    • (2003) J. Virol. , vol.77 , pp. 366-374
    • Pettit, S.C.1    Gulnik, S.2    Everitt, L.3    Kaplan, A.H.4
  • 25
    • 0036784575 scopus 로고    scopus 로고
    • Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by viral protease
    • Pettit, S. C., G. J. Henderson, C. A. Schiffer, and R. Swanstrom. 2002. Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by viral protease. J. Virol. 76:10226-10233.
    • (2002) J. Virol. , vol.76 , pp. 10226-10233
    • Pettit, S.C.1    Henderson, G.J.2    Schiffer, C.A.3    Swanstrom, R.4
  • 26
    • 0027971621 scopus 로고
    • The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions
    • Pettit, S. C., M. D. Moody, R. S. Wehbie, A. H. Kaplan, P. V. Nantermet, C. A. Klein, and R. Swanstrom. 1994. The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions. J. Virol. 68:8017-8027.
    • (1994) J. Virol. , vol.68 , pp. 8017-8027
    • Pettit, S.C.1    Moody, M.D.2    Wehbie, R.S.3    Kaplan, A.H.4    Nantermet, P.V.5    Klein, C.A.6    Swanstrom, R.7
  • 28
    • 0034044313 scopus 로고    scopus 로고
    • Estimating the rate of molecular evolution: Incorporating non-contemporaneous sequences into maximum likelihood phylogenetics
    • Rambaut, A. 2000. Estimating the rate of molecular evolution: incorporating non-contemporaneous sequences into maximum likelihood phylogenetics. Bioinformatics 16:395-399.
    • (2000) Bioinformatics , vol.16 , pp. 395-399
    • Rambaut, A.1
  • 29
    • 0029939026 scopus 로고    scopus 로고
    • Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids in adjacent enzyme subsites
    • Ridky, T. W., C. E. Cameron, J. Cameron, J. Leis, T. Copeland, A. Wlodawer, I. T. Weber, and R. W. Harrison. 1996. Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids in adjacent enzyme subsites. J. Biol. Chem. 271:4709-4717.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4709-4717
    • Ridky, T.W.1    Cameron, C.E.2    Cameron, J.3    Leis, J.4    Copeland, T.5    Wlodawer, A.6    Weber, I.T.7    Harrison, R.W.8
  • 30
    • 0035141859 scopus 로고    scopus 로고
    • Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents
    • Rodenburg, C. M., Y. Li, and S. A. Trask. 2001. Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents. AIDS Res. Hum. Retrovir. 17:161-168.
    • (2001) AIDS Res. Hum. Retrovir. , vol.17 , pp. 161-168
    • Rodenburg, C.M.1    Li, Y.2    Trask, S.A.3
  • 31
    • 0034796179 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 env sequences from Calcutta in eastern India: Identification of features that distinguish subtype C sequences in India from other subtype C sequences
    • Shankarappa, R., R. Chatterjee, and C. Learn. 2001. Human immunodeficiency virus type 1 env sequences from Calcutta in eastern India: identification of features that distinguish subtype C sequences in India from other subtype C sequences. J. Virol. 75:10479-10487.
    • (2001) J. Virol. , vol.75 , pp. 10479-10487
    • Shankarappa, R.1    Chatterjee, R.2    Learn, C.3
  • 32
    • 0034856077 scopus 로고    scopus 로고
    • Proteolytic processing of the p2/nucleocapsid cleavage site is critical for human immunodeficiency virus type 1 RNA dimer maturation
    • Shehu-Xhilaga, M., H. G. Kraesslich, S. Pettit, R. Swanstrom, J. Y. Lee, J. A. Marshall, S. M. Crowe, and J. Mak. 2001. Proteolytic processing of the p2/nucleocapsid cleavage site is critical for human immunodeficiency virus type 1 RNA dimer maturation. J. Virol. 75:9156-9164.
    • (2001) J. Virol. , vol.75 , pp. 9156-9164
    • Shehu-Xhilaga, M.1    Kraesslich, H.G.2    Pettit, S.3    Swanstrom, R.4    Lee, J.Y.5    Marshall, J.A.6    Crowe, S.M.7    Mak, J.8
  • 33
    • 0028598812 scopus 로고
    • The Genetic Data Environment: An expandable GUI for multiple sequence analysis
    • Smith, S. W., R. Overbeek, C. R., Woese, W. Gilbert, and P. M. Gillevet. 1994. The Genetic Data Environment: an expandable GUI for multiple sequence analysis. Comput. Appl. Sci. 10:671-675.
    • (1994) Comput. Appl. Sci. , vol.10 , pp. 671-675
    • Smith, S.W.1    Overbeek, R.2    Woese, C.R.3    Gilbert, W.4    Gillevet, P.M.5
  • 35
    • 0001118596 scopus 로고    scopus 로고
    • Retroviral gene expression. II. Synthesis, processing, and assembly of viral proteins
    • J. M. Coffin, S. H. Hughes, and H. E. Varmus (ed.). Cold Spring Harbor. Laboratory, Cold Spring Harbor, N.Y.
    • Swanstrom, R., and J. W. Wills. 1997. Retroviral gene expression. II. Synthesis, processing, and assembly of viral proteins, p. 263-334. In J. M. Coffin, S. H. Hughes, and H. E. Varmus (ed.), Retroviruses. Cold Spring Harbor. Laboratory, Cold Spring Harbor, N.Y.
    • (1997) Retroviruses , pp. 263-334
    • Swanstrom, R.1    Wills, J.W.2
  • 36
    • 0035659973 scopus 로고    scopus 로고
    • The public health significance of HIV-1 subtypes
    • Tatt, I. D., K. L. Barlow, A. Nicoll, and J. P. Clewley. 2001. The public health significance of HIV-1 subtypes. AIDS 15:S59-S71.
    • (2001) AIDS , vol.15
    • Tatt, I.D.1    Barlow, K.L.2    Nicoll, A.3    Clewley, J.P.4
  • 37
    • 2642680072 scopus 로고    scopus 로고
    • Cleavage of human immunodeficiency virus type 1 proteinase from the N-terminally adjacent p6* protein is essential for efficient Gag polyprotein processing and viral infectivity
    • Tessmer, U., and H.-G. Karausslich. 1998. Cleavage of human immunodeficiency virus type 1 proteinase from the N-terminally adjacent p6* protein is essential for efficient Gag polyprotein processing and viral infectivity. J. Virol. 72:3459-3463.
    • (1998) J. Virol. , vol.72 , pp. 3459-3463
    • Tessmer, U.1    Karausslich, H.-G.2
  • 38
    • 0029991762 scopus 로고    scopus 로고
    • Anti-idiotypic antibody to the V3 domain of gp120 binds to vimentin: A possible role of intermediate filaments in the early steps of HIV-1 infection cycle
    • Thomas, E. K., R. J. Connelly, S. Pennathur, L. Dubrovsky, O. K. Haffar, and M. I. Bukrinsky. 1996. Anti-idiotypic antibody to the V3 domain of gp120 binds to vimentin: a possible role of intermediate filaments in the early steps of HIV-1 infection cycle. Viral Immunol. 9:73-87.
    • (1996) Viral Immunol. , vol.9 , pp. 73-87
    • Thomas, E.K.1    Connelly, R.J.2    Pennathur, S.3    Dubrovsky, L.4    Haffar, O.K.5    Bukrinsky, M.I.6
  • 39
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignments through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignments through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 40
    • 0029052114 scopus 로고
    • Specificity of retroviral proteases: An analysis of viral and nonviral protein substrates
    • Tomasselli, A. G., and R. L. Heinrickson. 1994. Specificity of retroviral proteases: an analysis of viral and nonviral protein substrates. Methods Enzymol. 241:279-301.
    • (1994) Methods Enzymol. , vol.241 , pp. 279-301
    • Tomasselli, A.G.1    Heinrickson, R.L.2
  • 42
    • 0033045487 scopus 로고    scopus 로고
    • A predominantly HIV type 1 subtype C-restricted epidemic in South African urban populations
    • Van Harmelen, J. H., E. Van der Ryst, and S. A. Loubser. 1999. A predominantly HIV type 1 subtype C-restricted epidemic in South African urban populations. AIDS Res. Hum. Retrovir. 15:395-398.
    • (1999) AIDS Res. Hum. Retrovir. , vol.15 , pp. 395-398
    • Van Harmelen, J.H.1    Van der Ryst, E.2    Loubser, S.A.3
  • 43
    • 0035933060 scopus 로고    scopus 로고
    • Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes
    • Velazquez-Campoy, A., M. J. Todd, S. Vega, and E. Freire. 2001. Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes. Proc. Natl. Acad. Sci. USA 98:6062-6067.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6062-6067
    • Velazquez-Campoy, A.1    Todd, M.J.2    Vega, S.3    Freire, E.4
  • 44
    • 0033692959 scopus 로고    scopus 로고
    • Maximum likelihood estimation on large phylogenies and analysis of adaptive evolution in human influenza virus A
    • Yang, Z. 2000. Maximum likelihood estimation on large phylogenies and analysis of adaptive evolution in human influenza virus A. J. Mol. Evol. 51:423-432.
    • (2000) J. Mol. Evol. , vol.51 , pp. 423-432
    • Yang, Z.1
  • 45
    • 0034097381 scopus 로고    scopus 로고
    • Codon-substitution models for variable selection pressure at amino acid sites
    • Yang, Z., R. Nielsen, N. Goldman, and A.-M. K. Pedersen. 2000. Codon-substitution models for variable selection pressure at amino acid sites. Genetics 155:431-449.
    • (2000) Genetics , vol.155 , pp. 431-449
    • Yang, Z.1    Nielsen, R.2    Goldman, N.3    Pedersen, A.-M.K.4
  • 46
    • 0031946007 scopus 로고    scopus 로고
    • Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo
    • Zennou, V., F. Mammano, S. Paulous, D. Mathez, and F. Clavel. 1998. Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo. J. Virol. 72:3300-3306.
    • (1998) J. Virol. , vol.72 , pp. 3300-3306
    • Zennou, V.1    Mammano, F.2    Paulous, S.3    Mathez, D.4    Clavel, F.5
  • 47
    • 0030769354 scopus 로고    scopus 로고
    • Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites
    • Zhang, Y. M., H. Imamichi, T. Imamichi, H. C. Lane, J. Falloon, M. B. Vasudevachari, and N. P. Salzman. 1997. Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites. J. Virol. 71:6662-6670.
    • (1997) J. Virol. , vol.71 , pp. 6662-6670
    • Zhang, Y.M.1    Imamichi, H.2    Imamichi, T.3    Lane, H.C.4    Falloon, J.5    Vasudevachari, M.B.6    Salzman, N.P.7
  • 49
    • 0029013602 scopus 로고
    • Domains upstream of the protease (PR) in human immunodeficiency virus type I Gag-Pol influence PR autoprocessing
    • Zybarth, G., and C. Carter. 1995. Domains upstream of the protease (PR) in human immunodeficiency virus type I Gag-Pol influence PR autoprocessing. J. Virol. 69:3878-3884.
    • (1995) J. Virol. , vol.69 , pp. 3878-3884
    • Zybarth, G.1    Carter, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.