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Volumn 26, Issue 3, 2002, Pages 202-207

Animal models for the genetic study of human alcohol phenotypes

Author keywords

Alcoholic beverage, phenotype; Animal model, gene knockout, transgenic technology; Gene expression; Genetic correlation analysis; Genetic theory of AODU (alcohol and other drug use); Genetic trait; Mutagenesis; QTL (quantitative trait locus) mapping

Indexed keywords

ALCOHOLISM; ANIMAL; ARTICLE; DISEASE MODEL; GENETICS; METHODOLOGY; MOLECULAR BIOLOGY; MOUSE; MOUSE MUTANT; PHENOTYPE; POINT MUTATION; TRANSGENIC MOUSE;

EID: 0041850100     PISSN: 0090838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (41)
  • 1
    • 0034708480 scopus 로고    scopus 로고
    • The genome sequence of Drosophila melanogaster
    • ADAMS, M.D.; CELNIKER, S.E.; HOLT, R.A.; ET AL. The genome sequence of Drosophila melanogaster. Science 287:2185-2195, 2000.
    • (2000) Science , vol.287 , pp. 2185-2195
    • Adams, M.D.1    Celniker, S.E.2    Holt, R.A.3
  • 3
    • 0034891003 scopus 로고    scopus 로고
    • QTL analysis and genomewide mutagenesis in mice: Complementary genetic approaches to the dissection of complex traits
    • BELKNAP, J.K.; HITZEMANN, R.; CRABBE, J.C.; ET AL. QTL analysis and genomewide mutagenesis in mice: Complementary genetic approaches to the dissection of complex traits. Behavior Genetics 31:5-15, 2001.
    • (2001) Behavior Genetics , vol.31 , pp. 5-15
    • Belknap, J.K.1    Hitzemann, R.2    Crabbe, J.C.3
  • 4
    • 0034973416 scopus 로고    scopus 로고
    • A high-resolution consensus linkage map of the rat, integrating radiation hybrid and genetic maps
    • BIHOREAU, M.T.; SEBAG-MONTEFIORE, L.; GODFREY, R.F.; ET AL. A high-resolution consensus linkage map of the rat, integrating radiation hybrid and genetic maps. Genomics 75:57-69, 2001.
    • (2001) Genomics , vol.75 , pp. 57-69
    • Bihoreau, M.T.1    Sebag-Montefiore, L.2    Godfrey, R.F.3
  • 5
    • 0034478075 scopus 로고    scopus 로고
    • Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research
    • CARLEZON, W.A., JR.; NESTLER, E.J.; AND NEVE, R.L. Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research. Critical Reviews in Neurobiology 14:47-67, 2000.
    • (2000) Critical Reviews in Neurobiology , vol.14 , pp. 47-67
    • Carlezon Jr., W.A.1    Nestler, E.J.2    Neve, R.L.3
  • 6
    • 0031815148 scopus 로고    scopus 로고
    • A quantitative trait locus for alcohol consumption in selectively bred rat lines
    • CARR, L.G.; FOROUD, T.; BICE, P.; ET AL. A quantitative trait locus for alcohol consumption in selectively bred rat lines. Alcoholism: Clinical and Experimental Research 22:884-887, 1998.
    • (1998) Alcoholism: Clinical and Experimental Research , vol.22 , pp. 884-887
    • Carr, L.G.1    Foroud, T.2    Bice, P.3
  • 7
    • 0033118963 scopus 로고    scopus 로고
    • Identifying genes for alcohol and drug sensitivity: Recent progress and future directions
    • CRABBE, J.C.; PHILLIPS, T.J.; BUCK, K.J.; ET AL. Identifying genes for alcohol and drug sensitivity: Recent progress and future directions. Trends in Neuroscience 22:173-179, 1999.
    • (1999) Trends in Neuroscience , vol.22 , pp. 173-179
    • Crabbe, J.C.1    Phillips, T.J.2    Buck, K.J.3
  • 8
    • 0345274805 scopus 로고    scopus 로고
    • Genetic basis of ethanol reward
    • Maldonado, R., ed. Totowa, NJ: Humana Press
    • CUNNINGHAM, C.L., AND PHILLIPS, T.J. Genetic basis of ethanol reward. In: Maldonado, R., ed. Molecular Biology of Drug Addiction. Totowa, NJ: Humana Press, 2003. pp. 263-294.
    • (2003) Molecular Biology of Drug Addiction , pp. 263-294
    • Cunningham, C.L.1    Phillips, T.J.2
  • 10
    • 0033546155 scopus 로고    scopus 로고
    • Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid
    • DELTOUR, L.; FOGLIO, M.H.; AND DUESTER, G. Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid. Journal of Biological Chemistry 274:16796-16801, 1999.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 16796-16801
    • Deltour, L.1    Foglio, M.H.2    Duester, G.3
  • 11
    • 17844381297 scopus 로고    scopus 로고
    • High-throughput sequence identification of gene coding variants within alcohol-related QTLs
    • EHRINGER, M.A.; THOMPSON, J.; CONROY, O.; ET AL. High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mammalian Genome 12:657-663, 2001.
    • (2001) Mammalian Genome , vol.12 , pp. 657-663
    • Ehringer, M.A.1    Thompson, J.2    Conroy, O.3
  • 12
    • 0033844787 scopus 로고    scopus 로고
    • Identification of quantitative trait loci influencing alcohol consumption in the high alcohol drinking and low alcohol drinking rat lines
    • FOROUD, T.; BICE, P.; CASTELLUCCIO, P.; ET AL. Identification of quantitative trait loci influencing alcohol consumption in the high alcohol drinking and low alcohol drinking rat lines. Behavior Genetics 30:131-140, 2000.
    • (2000) Behavior Genetics , vol.30 , pp. 131-140
    • Foroud, T.1    Bice, P.2    Castelluccio, P.3
  • 13
    • 0035048109 scopus 로고    scopus 로고
    • Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression
    • FREEMAN, W.M.; NADER, M.A.; NADER, S.H.; ET AL. Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression. Journal of Neurochemistry 77:542-549, 2001.
    • (2001) Journal of Neurochemistry , vol.77 , pp. 542-549
    • Freeman, W.M.1    Nader, M.A.2    Nader, S.H.3
  • 14
    • 0034486729 scopus 로고    scopus 로고
    • Drinks like a fish: Zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects
    • GERLAI, R.; LAHAV, M.; GUO, S.; AND ROSENTHAL, A. Drinks like a fish: Zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects. Pharmacology Biochemistry and Behavior 67:773-782, 2000.
    • (2000) Pharmacology Biochemistry and Behavior , vol.67 , pp. 773-782
    • Gerlai, R.1    Lahav, M.2    Guo, S.3    Rosenthal, A.4
  • 15
    • 0033969701 scopus 로고    scopus 로고
    • The broken mouse: The role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice
    • GINGRICH, J.A., AND HEN, R. The broken mouse: The role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Current Opinion in Neurobiology 10:146-152, 2000.
    • (2000) Current Opinion in Neurobiology , vol.10 , pp. 146-152
    • Gingrich, J.A.1    Hen, R.2
  • 16
    • 0035057121 scopus 로고    scopus 로고
    • Towards a molecular epidemiology of alcohol dependence: Analysing the interplay of genetic and environmental risk factors
    • HEATH, A.C.; WHITFIELD, J.B.; MADDEN, P.A.; ET AL. Towards a molecular epidemiology of alcohol dependence: Analysing the interplay of genetic and environmental risk factors. British Journal of Psychiatry 178 (Suppl. 40):s33-s40, 2001.
    • (2001) British Journal of Psychiatry , vol.178 , Issue.40 SUPPL.
    • Heath, A.C.1    Whitfield, J.B.2    Madden, P.A.3
  • 17
    • 0034566268 scopus 로고    scopus 로고
    • Genetics of alcohol-induced behaviors in Drosophila
    • HEBERLEIN, U. Genetics of alcohol-induced behaviors in Drosophila. Alcohol Research & Health 24:185-188, 2000.
    • (2000) Alcohol Research & Health , vol.24 , pp. 185-188
    • Heberlein, U.1
  • 18
    • 84943244825 scopus 로고    scopus 로고
    • Knockout and knockin mice
    • Liu, Y., and Lovinger, D.M., eds. Washington DC: CRC Press
    • HOMANICS, G.E. Knockout and knockin mice. In: Liu, Y., and Lovinger, D.M., eds. Methods in Alcohol-Related Neuroscience Research. Washington DC: CRC Press, 2002. pp. 31-61.
    • (2002) Methods in Alcohol-Related Neuroscience Research , pp. 31-61
    • Homanics, G.E.1
  • 19
    • 0034770193 scopus 로고    scopus 로고
    • Association of neuropeptide Y polymorphism with the occurrence of type 1 and type 2 alcoholism
    • ILVESKOSKI, E.; KAJANDER, O.A.; LEHTIMAKI, T.; ET AL. Association of neuropeptide Y polymorphism with the occurrence of type 1 and type 2 alcoholism. Alcoholism: Clinical and Experimental Research 25:1420-1422, 2001.
    • (2001) Alcoholism: Clinical and Experimental Research , vol.25 , pp. 1420-1422
    • Ilveskoski, E.1    Kajander, O.A.2    Lehtimaki, T.3
  • 21
    • 0033913720 scopus 로고    scopus 로고
    • Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference
    • KIMMEL, H.L.; GONG, W.; VECHIA, S.D.; ET AL. Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference. Journal of Pharmacology and Experimental Therapeutics 294:784-792, 2000.
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.294 , pp. 784-792
    • Kimmel, H.L.1    Gong, W.2    Vechia, S.D.3
  • 22
    • 0034821702 scopus 로고    scopus 로고
    • Efficacy of naltrexone and acamprosate for alcoholism treatment: A meta-analysis
    • KRANZLER, H.R., AND VAN KIRK, J. Efficacy of naltrexone and acamprosate for alcoholism treatment: A meta-analysis. Alcoholism: Clinical and Experimental Research 25:1335-1341, 2001.
    • (2001) Alcoholism: Clinical and Experimental Research , vol.25 , pp. 1335-1341
    • Kranzler, H.R.1    Van Kirk, J.2
  • 24
    • 0035840788 scopus 로고    scopus 로고
    • Alcoholism, ALDH2*2 allele and the A1 allele of the dopamine D2 receptor gene: An association study
    • MATSUSHITA, S.; MURAMATSU, T.; MURAYAMA, M.; ET AL. Alcoholism, ALDH2*2 allele and the A1 allele of the dopamine D2 receptor gene: An association study. Psychiatry Research 104:19-26, 2001.
    • (2001) Psychiatry Research , vol.104 , pp. 19-26
    • Matsushita, S.1    Muramatsu, T.2    Murayama, M.3
  • 25
    • 0034917401 scopus 로고    scopus 로고
    • Trans-NIH neuroscience initiatives on mouse phenotyping and mutagenesis
    • MOLDIN, S.O.; FARMER, M.E.; CHIN, H.R.; AND BATTEY, J.F. JR. Trans-NIH neuroscience initiatives on mouse phenotyping and mutagenesis. Mammalian Genome 12:575-581, 2001.
    • (2001) Mammalian Genome , vol.12 , pp. 575-581
    • Moldin, S.O.1    Farmer, M.E.2    Chin, H.R.3    Battey Jr., J.F.4
  • 27
    • 0034252558 scopus 로고    scopus 로고
    • The DRD2 gene in psychiatric and neurological disorders and its phenotypes
    • NOBLE, E.P. The DRD2 gene in psychiatric and neurological disorders and its phenotypes. Pharmacogenomics 1:309-333, 2000.
    • (2000) Pharmacogenomics , vol.1 , pp. 309-333
    • Noble, E.P.1
  • 28
    • 0003304633 scopus 로고    scopus 로고
    • Quantitative trait locus mapping in mice
    • Liu, Y., and Lovinger, D.M., eds. Washington, DC: CRC Press
    • PALMER, A.A., AND PHILLIPS, T.J. Quantitative trait locus mapping in mice. In: Liu, Y., and Lovinger, D.M., eds. Methods in Alcohol-Related Neuroscience Research. Washington, DC: CRC Press, 2002. pp. 1-30.
    • (2002) Methods in Alcohol-Related Neuroscience Research , pp. 1-30
    • Palmer, A.A.1    Phillips, T.J.2
  • 31
    • 0345034780 scopus 로고    scopus 로고
    • Expression of ZFOR1, a δ-opioid receptor, in the central nervous system of the zebrafish (Danio rerio)
    • PORTEROS, A.; GARCIA-ISIDORO, M.; BARRALLO, A.; ET AL. Expression of ZFOR1, a δ-opioid receptor, in the central nervous system of the zebrafish (Danio rerio). Journal of Comparative Neurology 412:429-438, 1999.
    • (1999) Journal of Comparative Neurology , vol.412 , pp. 429-438
    • Porteros, A.1    Garcia-Isidoro, M.2    Barrallo, A.3
  • 32
    • 0035859815 scopus 로고    scopus 로고
    • Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized
    • RUAN, Y.; TECOTT, L; JIANG, M.-M.; ET AL. Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized. Proceedings of the National Academy of Sciences of the USA 98:9907-9912, 2001.
    • (2001) Proceedings of the National Academy of Sciences of the USA , vol.98 , pp. 9907-9912
    • Ruan, Y.1    Tecott, L.2    Jiang, M.-M.3
  • 33
    • 0032445401 scopus 로고    scopus 로고
    • Y do we drink?
    • TECOTT, L.H., AND HEBERLEIN, U. Y do we drink? Cell 95:733-735, 1998.
    • (1998) Cell , vol.95 , pp. 733-735
    • Tecott, L.H.1    Heberlein, U.2
  • 34
    • 0034844411 scopus 로고    scopus 로고
    • Overexpression of dopamine D2 receptors reduces alcohol self-administration
    • THANOS, P.K.; VOLKOW, N.D.; FREIMUTH, P.; ET AL. Overexpression of dopamine D2 receptors reduces alcohol self-administration. Journal of Neurochemistry 78:1094-1103, 2001.
    • (2001) Journal of Neurochemistry , vol.78 , pp. 1094-1103
    • Thanos, P.K.1    Volkow, N.D.2    Freimuth, P.3
  • 35
    • 0034656653 scopus 로고    scopus 로고
    • High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice
    • THIELE, T.E.; WILLIS, B.; STADLER, J.; ET AL. High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice. Journal of Neuroscience 20(RC75): 1-6, 2000.
    • (2000) Journal of Neuroscience , vol.20 , Issue.RC75 , pp. 1-6
    • Thiele, T.E.1    Willis, B.2    Stadler, J.3
  • 36
    • 0035209299 scopus 로고    scopus 로고
    • Polysubstance abuse-vulnerability genes: Genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms
    • UHL, G.R.; LIU, Q.-R.; WALTHER, D.; ET AL. Polysubstance abuse-vulnerability genes: Genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms. American Journal of Human Genetics 69:1290-1300, 2001.
    • (2001) American Journal of Human Genetics , vol.69 , pp. 1290-1300
    • Uhl, G.R.1    Liu, Q.-R.2    Walther, D.3
  • 37
    • 0034554823 scopus 로고    scopus 로고
    • Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance
    • WAGGONER, L.E.; DICKINSON, K.A.; POOLE, D.S.; ET AL. Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance. Journal of Neuroscience 20:8802-8811, 2000.
    • (2000) Journal of Neuroscience , vol.20 , pp. 8802-8811
    • Waggoner, L.E.1    Dickinson, K.A.2    Poole, D.S.3
  • 38
    • 0035078936 scopus 로고    scopus 로고
    • Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats
    • WHEELER, M.D.; KONO, H.; YIN, M.; ET AL. Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats. Gastroenterology 120:12411-1250, 2001.
    • (2001) Gastroenterology , vol.120 , pp. 12411-21250
    • Wheeler, M.D.1    Kono, H.2    Yin, M.3
  • 39
    • 0034967563 scopus 로고    scopus 로고
    • Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization
    • XU, Y.; EHRINGER, M.; YANG, F.; AND SIKELA, J.M. Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization. Alcoholism: Clinical and Experimental Research 25:810-818, 2001.
    • (2001) Alcoholism: Clinical and Experimental Research , vol.25 , pp. 810-818
    • Xu, Y.1    Ehringer, M.2    Yang, F.3    Sikela, J.M.4
  • 40
    • 0035937536 scopus 로고    scopus 로고
    • Increased levels of calcium-sensitive adenylyl cyclase subtypes in the limbic system of alcoholics: Evidence for a specific role of cAMP signaling in the human addictive brain
    • YAMAMOTO, M.; POHLI, S.; DURANY, N.; ET AL. Increased levels of calcium-sensitive adenylyl cyclase subtypes in the limbic system of alcoholics: Evidence for a specific role of cAMP signaling in the human addictive brain. Brain Research 895:233-237, 2001.
    • (2001) Brain Research , vol.895 , pp. 233-237
    • Yamamoto, M.1    Pohli, S.2    Durany, N.3
  • 41
    • 0034885773 scopus 로고    scopus 로고
    • Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae
    • ZU, T.; VERNA, J.; AND BALLESTER, R. Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae. Molecular Genetics and Genomics 266:142-155, 2001.
    • (2001) Molecular Genetics and Genomics , vol.266 , pp. 142-155
    • Zu, T.1    Verna, J.2    Ballester, R.3


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