Spectrophotometric and liquid chromatographic determination of trimebutine maleate in the presence of its degradation products

Journal of Pharmaceutical and Biomedical Analysis

Volumn 33, Issue 2, 2003, Pages 231-241

  El Gindy, Alaa ^a   Emara, Samy ^a   Hadad, Ghada M ^a  

^a Suez Canal University   (Egypt)

Author keywords

First derivative spectrophotometry; HPLC; Kinetics of degradation; PH rate profile; Trimebutine

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID; ACETONITRILE; SPASMOLYTIC AGENT; SULFONIC ACID DERIVATIVE; TRIMEBUTINE MALEATE;

ACIDITY; ALKALINITY; ANALYTIC METHOD; ARTICLE; DRUG DEGRADATION; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SPECTROPHOTOMETRY; TEMPERATURE; ULTRAVIOLET SPECTROSCOPY;

EID: 0041825166     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00285-1     Document Type: Article

References (15)

1. Parfitt K. Martindale - The Complete Drug Reference. 32nd ed:1999;1639 Pharmaceutical Press, London.
2. Abdel-Gawad F.M. J. Pharm. Biomed. Anal. 16:1998;793-799.
3. S.M. Khalil, National Organization For Drug Control And Research, Sixth Scientific Conference, Quality Control Of Drugs, Vaccines and Natural Products, Cairo, Egypt, March 2002, p. 30.
4. Astier A., Deutsch A.M. J. Chromatogr. 224:1981;149-155.
5. Shehata M.A.M., Abdel-Barry A. Bull. Fac. Pharm. Cairo Univ. 37:1999;175-180.
6. Lavit M., Saivin S., Boudra H., Michel F., Martin A., Cahiez G., La J., Chomard J., Houin G. Arzneimittelforschung. 50:2000;640-644.
7. Joo E.H., Chang W.I., Oh I., Shin S.C., Na H.K., Lee Y.B. J. Chromatogr. B. Biomed. Appl. 723:1999;239-246.
8. Wang H., Zhou H., Horimoto S., Jiang J., Mayumi T., Hu P. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 779:(2):2002;173-187.
9. Lin Z.H., Song M. Yaowu Fenxi Zazhi. 21:2001;25-28.
10. Yu L.N., Li F.M. Fenxi Huaxue. 29:2001;785-787.
11. Yu L.N., Li F.M. Yaowu Fenxi Zazhi. 21:2001;48-50.
12. Li F.M., Yu L.N. Biomed. Chromatogr. 15:2001;248-251.
13. Brezina M., Zuman P. Polarography in Medicine, Biochemistry, and Pharmacy. 1958;731 Interscience, New York.
14. Morelli B. Talanta. 41:1994;673-683.
15. The European Agency for The Evaluation of Medical Products. ICH Topic Q2B Note for Guidance on Validation of Analytical Procedures: Methodology GPMP/ICH/281/95, 1996.