Functional type I PTH/PTHrP receptor in freshly isolated newborn rat keratinocytes: Identification by RT-PCR and immunohistochemistry

Journal of Bone and Mineral Research

Volumn 18, Issue 4, 2003, Pages 737-750

  Errazahi, Amina ^a   Bouizar, Zhor ^b   Lieberherr, Michele ^a   Souil, Evelyne ^a   Rizk Rabin, Marthe ^a,c  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

Immunohistochemistry; Keratinocytes; Reverse transcription polymerase chain reaction; Sequencing; Type I parathyroid hormone parathyroid hormone related peptide receptor

Indexed keywords

CELL EXTRACT; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE RECEPTOR ANTIBODY; PARATHYROID HORMONE RELATED PEPTIDE[7-34][10 ASPARAGINE 11 LEUCINE 12 DEXTRO TRYPTOPHAN]; PARATHYROID HORMONE RELATED PROTEIN 1 RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN RECEPTOR; PARATHYROID HORMONE[1-34]; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONTROLLED STUDY; DNA CONTENT; DNA SEQUENCE; EPIDERMIS; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; NEWBORN; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

EID: 0041805426     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.4.737     Document Type: Article

References (40)

1. Merendino JJ, Insogna KL, Milstone LM, Broadus AE, Stewart AF, Broadus AE, Stewart AF 1986 Parathyroid hormone related-like protein from cultured human keratinocytes. Science 231:388-390.
2. Holick MF, Ray S, Chen TC, Tian X, Persons KS 1994 A parathyroid antagonist stimulates epidermal proliferation and hair growth in mice. Proc Natl Acad Sci USA 91:8014-8016.
3. Foley J, Longely BJ, Wysolmerski JJ, Dreyer BE, Broadus AE, Philbrick WM 1998 PTHrP regulates epidermal differentiation in adult mice. J Invest Dermatol 111:1122-1128.
4. Werkmeister JR, Merryman JI, McCauley LK, Horton JE, Capen CC, Rosol TJ 1993 Parathyroid hormone related protein production by normal human keratinocytes in vitro. Exp Cell Res 208: 68-74.
5. Moseley JM, Hayman JA, Danks JA, Alcorn D, Grill V, Southby J, Horton MA 1991 Immunohistochemical detection of parathyroid hormone related protein in human fetal epithelia. J Clin Endocrinol Metab 73:478-484.
6. Lee K, Deeds JD, Segre GV 1995 Expression of parathyroid hormone related peptide and its receptor messenger ribonucleic acids during fetal development of rats. Endocrinology 136:453-463.
7. ++ signal transduction pathway. J Biol Chem 270: 151-156.
8. Whitfield JF, Balu R, Chakravarthy BR, Durkin JP, Issacs RJ, Jouishome H, Sikorska M, Williams RE, Rixon RH 1992 Parathyroid hormone stimulates protein kinase C but not adenylcyclase in mouse epidermal keratinocytes. J Cell Physiol 150:299-303.
9. Gaich G, Orloff JJ, Atillasoy EJ, Burtis WJ, Ganz MB, Stewart AF 1993 Amino terminal parathyroid related protein: Specific binding and cytosolic calcium responses in rat insulinoma cells. Endocrinology 132:1402-1409.
10. Orloff JJ, Kats Y, Urena P, Shipani E, Vasavada RC, Philbrick WM, Behal A, Abou-Samra AB, Segre GV, Juppner H 1995 Further evidence for a novel receptor for amino-terminal parathyroid hormone related protein on keratinocytes and squamous carcinoma cell lines. Endocrinology 136:3016-3023.
11. Vilanueva-Penacarrillo ML, Cancelas J, de Miguel F, Redondo A, Valin A, Valverde I, Eesbrit P 1999 Parathyroid hormone related peptide stimulates DNA synthesis and insulin secretion in pancreatic islets. J Endocrinol 163:403-408.
12. Urena P, Kong XF, Abou-Samra AB, Juppner H, Kronenberg HM, Potts JT, Segre GV 1993 Parathyroid hormone PTH/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues. Endocrinology 133:617-623.
13. Lavker RM, Sun TT 1982 Heterogeneity in epidermal basal keratinocytes: Morphological and functional correlations. Science 215: 1239-1241.
14. Pavlovitch JH, Rizk-Rabin M, Gervaise M, Metezeau P, Grunwald D 1989 Cell subpopulations within the proliferative and differentiating compartment of cell epidermis: Multiparameter analysis and selective sorting of epidermal stem cells. Am J Physiol 256: C977-C986.
15. Abou-Samra AB, Juppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736.
16. Cataisson C, Lieberherr M, Cros M, Gauville C, Graulet AM, Cotton J, Calvo F, de Vernejoul MC, Foley J, Bouizar Z 2000 Autocrine effect of parathyroid hormone-related peptide and alternative signaling pathways during malignant progression in human SV40-immortalized breast cell lines. J Bone Miner Res 15:2129-2139.
17. Nutt RF, Caulfield MP, Levy JJ, Gibbons SW, Rosenblatt M, McKee RL 1990 Removal of partial agonism from parathyroid hormone (PTH)-related protein (7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. Endocrinology 127:491-493.
18. Xie LY, Leung A, Segre GV, Yamamoto I, Abou-Samra AB 1996 Down regulation of the PTH/PTHrP receptor, by vitamin D3 in the osteoblast-like Ros 1712.8 cells. Am J Physiol 270:E654-E660.
19. Yuspa SH, Harris CC 1974 Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res 86:95-105.
20. Chomczynski PN, Sacchi N 1987 Single-step method of RNA isolation by acid guanidium thiocyanate phenol-chloroform extraction. Anal Biochem 162:156-159.
21. Cros M, Silve C, Graulet AM, Morieux C, Urena P, de Vernejoul MC, Bouizar Z 1998 Estrogen stimulates PTHrP but not PTH/PTHrP receptor gene expression in the kidney of ovariectomized rat. J Cell Biochem 70:84-93.
22. Moll RM, Franke WW, Schiller DL 1982 The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24.
23. Bradford M 1976 A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
24. Labarca C, Paigen K 1980 A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102:344-352.
25. Varani J 1998 Preservation of human skin structure and function in organ culture. Histol Histopathol 13:775-783.
26. Kong XF, Schipani E, Lanskee B, Joun H, Karperien HM, Defize LH, Juppner H, Potts JT Jr, Segre GV, Kronenberg HM, Abou-Samza AB 1994 The rat, mouse and human genes encoding the receptor for parathyroid hormone and parathyroid hormone-related peptide are highly homologous. Biochem Biophys Res Commun 200:1290-1299.
27. Watson PH, Fraher LJ, Hendy GN, Chung UI, Kisiel M, Natale BV, Hodsman AB 2000 Nuclear localization of the type I PTH/ PTHrP receptor in rat tissues. J Bone Miner Res 15:1033-1044.
28. Hayman JA, Danks JK, Ebelig PR, Mosley JM, Kemp BE, Martin TJ 1989 Expression of parathyroid hormone related protein in normal skin and in tumors of skin and skin appendages. J Pathol 158:293-296.
29. Blomme EAG, Werkmeister JR, Zhou H, Kartsogiannis V, Capen CC, Rosol TJ 1998 Parathyroid hormone related protein expression and secrefion in a skin organotypic culture system. Endocrine 8:143-151.
30. Arts MM, Rix A, Guo J, Bringhurst R, Henderson JE 1999 The nucleolar targeting signal (NTS) of parathyroid hormone related protein mediates endocytosis and nucleolar translocation. J Bone Miner Res 14:1493-1503.
31. Lam MH, Thomas RJ, Loveland KL, Schilders S, Gu M, Martin TJ, Gillepsie MT, Jans DA 2002 Nuclear transport of parathyroid hormone (PTH)-related protein is dependent on microtubules. Mol Endocrinol 16:390-401.
32. O'Keefe EJ, Chiu ML 1988 Stimulation of thymidine incorporation in keratinocytes by insulin, epidermal growth factor and placental extract: Comparison with cell number to assess growth. J Invest Dermatol 90:2-7.
33. Henderson JE, Kremer K, Rhim JS, Goltzman D 1992 Identification of adenylate cyclase receptors for parathyroid hormone like peptides on immortalized human keratinocytes. Endocrinology 130:449-457.
34. Kaiser SM, Laneuville P, Bernier SM, Rhim JS, Kremer R, Goltzman D 1992 Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide. J Biol Chem 267:13623-13628.
35. Kaiser SM, Sebag M, Rhim JS, Kremer R, Goltzman DC 1992 Antisense-mediated inhibition of parathyroid hormone related peptide production in a keratinocyte cell line impedes differentiation. Mol Endocrinol 8:139-147.
36. Hanafin NM, Chen TC, Heunrich G, Segre GV, Holick MF 1995 Cultured human fibroblasts and not cultured human keratinocytes express a PTH/PTHrP receptor mRNA. J Invest Dermatol 105: 133-137.
37. Pausova Z, Bourdon J, Clayton D, Mattei M-G, Seldin MF, Janicic N, Riviere M, Szpirer J, Levan G, Sziper C, Goltzman D, Hendy GN 1994 Cloning of a Parathyroid hormone/Parathyroid hormone related peptide receptor (PTHR) cDNA from a rat osteosarcoma (UMR 106) cell line/Chromosomal assignment of the gene in the human, mouse and rat genomes. Genomics 20:20-26.
38. Wysolmerski JJ, Philbrick WM, Zhou J, Broadus AE, Milstone LM 1994 Overexpression of parathyroid hormone related protein in the skin of transgenic mice interferes with hair follicle development. Proc Natl Acad Sci USA 91:1133-1137.
39. Ebeling PR, Adam WR, Moseley JM, Martin TJ 1989 Actions of synthetic parathyroid hormone related protein (1-34) on the isolated rat kidney. J Endocrinol 120:45-50.
40. Insigna KL, Stewart AF, Morris CA, Hough LM, Milstone LM, Centrella M 1989 Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties. J Clin Invest 83:1057-1060.