Review article: Inflammation-related promotion of gastrointestinal carcinogenesis - A perigenetic pathway

Alimentary Pharmacology and Therapeutics, Supplement

Volumn 18, Issue 1, 2003, Pages 82-89

  Tsuji, S ^a   Kawai, N ^a   Tsujii, M ^a   Kawano, S ^b   Hori, M ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BETA CATENIN; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FREE RADICAL; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL CLONE; CELL MIGRATION; CONFERENCE PAPER; DIGESTIVE SYSTEM CANCER; DRUG TARGETING; GENE MUTATION; GENETIC ANALYSIS; HELICOBACTER PYLORI; HUMAN; INFLAMMATION; INTESTINE EPITHELIUM CELL; MALIGNANT TRANSFORMATION; NONHUMAN; ONCOGENE SRC; PHENOTYPE; PRIORITY JOURNAL; CELL COMMUNICATION; GASTROENTERITIS; GASTROINTESTINAL TUMOR; PATHOLOGY; PHYSIOLOGY; REVIEW;

CELL COMMUNICATION; CYTOKINES; GASTROENTERITIS; GASTROINTESTINAL NEOPLASMS; HUMANS;

EID: 0041783521     PISSN: 09530673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.18.s1.22.x     Document Type: Conference Paper

References (52)

1. Kuper H, Adami HO, Trichopoulos D. Infections as a major preventable cause of human cancer. J Intern Med 2000; 248: 171-83.
2. Correa P, Fox J, Fontham E, et al. Helicobacter pylori and gastric carcinoma: serum antibody prevalence in populations with contrasting cancer risks. Cancer 1990; 66: 2569-74.
3. Loffeld RJLF, Willems I, Flendrig JA, Arends JW. Helicobacter pylori and gastric carcinoma. Histopathology 1990; 17: 537-41.
4. Parsonnet J, Friedmann GD, Vandersteen DP, et al. Helicobacter pylori infection and the risk of gastric carcinoma. New Engl J Med 1991; 325: 1127-31.
5. Nomura A, Stemmermann GN, Chyou PH, Kato I, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. New Engl J Med 1991; 325: 1132-6.
6. Forman D, Newell DG, Fullerton F, et al. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. BMJ 1991; 302: 1302-5.
7. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991; 338: 1175-6.
8. Erdman SE, Correa P, Coleman LA, Schrenzel MD, Li X, Fox JG. Helicobacter mustelae-associated gastric MALT lymphoma in ferrets. Am J Pathol 1997; 151: 273-80.
9. Enno A, O'Rourke J, Braye S, Howlett R, Lee A. Antigen-dependent progression of mucosa-associated lymphoid tissue (MALT)-type lymphoma in the stomach. Effects of antimicrobial therapy on gastric MALT lymphoma in mice. Am J Pathol 1998; 152: 1625-32.
10. Ward JM, Fox JG, Anver MR, et al. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. J Natl Cancer Inst 1994; 86: 1222-7.
11. Fox JG, Li X, Yan L, et al. Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: a model of Helicobacter-induced carcinogenesis. Infect Immun 1996; 64: 1548-58.
12. Welton JC, Marr JS, Friedman SM. Association between hepatobiliary cancer and typhoid carrier state. Lancet 1979; 1: 791-4.
13. Caygill CP, Hill MJ, Braddick M, Sharp JC. Cancer mortality in chronic typhoid and paratyphoid carriers. Lancet 1994; 343: 83-4.
14. Barthold SW, Jonas AM. Morphogenesis of early 1, 2-dimethylhydrazine-induced lesions and latent period reduction of colon carcinogenesis in mice by a variant of Citrobacter freundii. Cancer Res 1977; 37: 4352-60.
15. Newman JV, Kosaka T, Sheppard BJ, Fox JG, Schauer DB. Bacterial infection promotes colon tumorigenesis in Apc (Min/+) mice. J Infect Dis 2001; 184: 227-30.
16. Caygill CP, Braddick M, Hill MJ, Knowles RL, Sharp JC. The association between typhoid carriage, typhoid infection and subsequent cancer at a number of sites. Eur J Cancer Prev 1995; 4: 187-93.
17. Tsuji S, Kawano S, Tsujii M, et al. Helicobacter pylori extract stimulates inflammatory nitric oxide production. Cancer Lett 1996; 108: 195-200.
18. Mannick EE, Bravo LE, Zarama G, et al. Indible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res 1996; 56: 3238-43.
19. Wilson KT, Ramanujam KS, Mobley HL, Musselman RF, James SP, Meltzer SJ. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology 1996; 111: 1524-33.
20. Kimura A, Tsuji S, Tsujii M, et al. Expression of cyclo-oxygenase-2 and nitrotyrosine in human gastric mucosa before and after Helicobacter pylori eradication. Prostagland Leukotri Ess Fatty Acids 2000; 63: 315-22.
21. Aries V, Crowther JS, Drasar BS, Hill MJ, Williams RE. Bacteria and the aetiology of cancer of the large bowel. Gut 1969; 10: 334-5.
22. Tsujii M, Kawano S, Tsuji S, et al. Ammonia: a possible promotor in Helicobacter pylori-related gastric carcinogenesis. Cancer Lett 1992; 65: 15-8.
23. Tsujii M, Kawano S, Tsuji S, et al. Mechanism for ammonia-induced promotion of gastric carcinogenesis in rats. Carcinogenesis 1995; 16: 563-6.
24. Tsujii M, Kawano S, Tsuji S, Fusamoto H, Kamada T, Sato N. Mechanism of gastric mucosal damage induced by ammonia. Gastroenterology 1992; 102: 1881-8.
25. Kawano S, Tsujii M, Fusamoto H, Sato N, Kamada T. Chronic effect of intragastric ammonia on gastric mucosal structure in rats. Dig Dis Sci 1991; 36: 33-8.
26. Kawano S, Tsujii M, Tsuji S, et al. Effects of ammonia on Helicobacter pylori-associated gastric disease. Eur J Gastroenterol Hepatol 1993; 5(Suppl. 1): 29-33(S).
27. Tsujii M, Kawano S, Tsuji S, et al. Cell kinetics of mucosal atrophy in rat stomach induced by long-term administration of ammonia. Gastroenterology 1993; 104: 796-801.
28. Asahi M, Azuma T, Ito S, et al. Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med 2000; 191: 587-92.
29. Selbach M, Moese S, Hauck CR, Meyer TF, Backert S. Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem 2002; 277: 6775-8.
30. Stein M, Baqnoli F, Halenbeck R, Rappuoli R, Fanti WJ, Covacci A. c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol Microbiol 2002; 43: 971-80.
31. Higashi H, Tsutsumi R, Muto S, et al. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science 2002; 295: 683-6.
32. Li W, Nishimura R, Kashishian A, et al. A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol Cell Biol 1994; 14: 509-17.
33. Benett AM, Hausdorff SF, O'Reilly AM, Freeman RM, Neel BG. Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol Cell Biol 1996; 16: 1189-202.
34. Crabtree JE, Farmery SM, Lindley IJD, Figura N, Peichl P, Tompkins DS. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol 1994; 47: 945-50.
35. Mitsuno Y, Yoshida H, Maeda S, et al. Helicobacter pylori induced transactivation of SRE and AP-1 through the ERK signaling pathway in gastric cancer cells. Gut 2001; 49: 18-22.
36. Kwok T, Backert S, Schwarz H, Berger J, Meyer TF. Specific entry of Helicobacter pylori into cultured gastric epithelial cells via a zipper-like mechanism. Infect Immun 2002; 70: 2108-20.
37. Supajatura V, Ushio H, Wada A, et al. Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines. J Immunol 2002; 168: 2606-7.
38. Hudson JD, Shoabi MA, Maestro R, Carnero A, Hannon GJ, Beach DH. A proinflammatory cytokine inhibits p53 tumor suppressor activity. J Exp Med 1999; 190: 1375-82.
39. Cordon-Cardo C, Prives C. At the crossroads of inflammation and tumorigenesis. J Exp Med 1999; 190: 1367-70.
40. Bernstein CN, Blanchard JF, Kliewer E, Wajda A. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer 2001; 91: 854-62.
41. Pitsch RJ, Becker JM, Dayton MT. The occurrence of colon cancer in patients with known premalignant colonic mucosal diseases. J Surg Res 1994; 57: 293-8.
42. Moore RJ, Owens DM, Stamp G, et al. Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat Med 1999; 5: 828-31.
43. Suganuma M, Okabe S, Marino NW, Sakai A, Sueoka E, Fujiki H. Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice. Cancer Res 1999; 59: 4516-8.
44. Kawai N, Tsuji S, Tsujii M, et al. Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells. Gastroenterology 2002; 122: 331-9.
45. Coffey RJ, McCutchen CM, Graves-Deal R, Polk WH. Transforming growth factors and related peptides in gastrointestinal neoplasia. J Cell Biochem Suppl 1992; 16G: 111-8.
46. Moghal N, Sternberg PW. Multiple positive and negative regulators of signaling by the EGF-receptor. Curr Opin Cell Biol 1999; 11: 190-6.
47. Page K, Li J, Hodge JA, et al. Characterization of a Rac1 signaling pathway to cyclin D (1) expression in airway smooth muscle cells. J Biol Chem 1999; 274: 22065-71.
48. Yoshikawa T, Naito Y, Tanigawa T, Kondo M. Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. Arzneimittelforschung 1993; 43: 363-6.
49. Hahm KB, Park IS, Kim YS, et al. Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells. Free Radic Biol Med 1997; 22: 711-6.
50. Banan A, Fitzpatrick L, Zhang Y, Keshavarzian A. OPC-compounds prevent oxidant-induced carbonylation and depolymerizaion of the F-actin cytoskeleton and intestinal hyperpermeability. Free Radic Biol Med 2001; 30: 287-98.
51. Hong WS, Jung HY, Yang SK, et al. The antioxidant effect of rebamipide on oxygen free radical production by H. pylori activated human neutrophils: in comparison with N-acetylcysteamine, ascorbic acid and glutathione. Pharmcol Res 2001; 44: 293-7.
52. Kawai N, Tsuji S, Tsujii M, et al. TNF-alpha induces production of VEGF in Src-expressing intestinal cells: a possible implication of radical scavengers in prevention of inflammation related carcinogenesis(Abstract). Gastroenterology 2002; 122(Suppl. 1): 379.