OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability

Free Radical Biology and Medicine

Volumn 30, Issue 3, 2001, Pages 287-298

  Banan, A ^a   Fitzpatrick, L ^b   Zhang, Y ^a   Keshavarzian, A ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b Otsuka Pharmaceuticals   (United States)

Author keywords

Antioxidants; Caco 2 cells; Dinitrophenylhydrazine (DNP) immunoreactivity; F and G actin; Free radicals; IBD; Intestinal permeability; Quantitative immunoblotting

Indexed keywords

2,4 DINITROPHENOL; CARBOXYLIC ACID DERIVATIVE; CYTOCHALASIN D; F ACTIN; G ACTIN; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; REACTIVE OXYGEN METABOLITE; REBAMIPIDE; TETOMILAST; UNCLASSIFIED DRUG;

ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL STRAIN CACO 2; CONTROLLED STUDY; CYTOSKELETON; DEPOLYMERIZATION; DOSE RESPONSE; DRUG EFFECT; GASTROINTESTINAL MUCOSA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOREACTIVITY; INTESTINE MUCOSA PERMEABILITY; OXIDATION; PRIORITY JOURNAL;

ACTINS; ALANINE; ANTIOXIDANTS; BLOTTING, WESTERN; CACO-2 CELLS; CYTOSKELETON; FLUORESCENT DYES; HUMANS; IMMUNOBLOTTING; INTESTINAL MUCOSA; MICROSCOPY, FLUORESCENCE; OXIDANTS; OXIDATION-REDUCTION; PERMEABILITY; QUINOLONES; REACTIVE OXYGEN SPECIES; THIAZOLES;

EID: 0035254810     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00471-8     Document Type: Article

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