Immunohistochemical comparison of anti-prion protein (PrP) antibodies in the CNS of mice infected with scrapie

Journal of Histochemistry and Cytochemistry

Volumn 51, Issue 8, 2003, Pages 1065-1071

  Liu, Wing Gee ^a   Brown, Debbie A ^a   Fraser, Janet R ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

CNS; Immunohistochemistry; PrP; Scrapie

Indexed keywords

LYSINE; MONOCLONAL ANTIBODY; PARAFORMALDEHYDE; PERIODATE; POLYCLONAL ANTIBODY; PRION PROTEIN; PRION PROTEIN ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE COURSE; HIPPOCAMPUS; IMMUNODETECTION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; SCRAPIE; TISSUE FIXATION;

ANIMALIA;

EID: 0041743826     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540305100810     Document Type: Article

References (26)

1. Baxter HC, Liu W-G, Forster JL, Aitken A, Fraser JR (2002) Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain. Neuroscience 109:5-14
2. Bell JE, Gentleman SM, Ironside JW, McCardle L, Lantos PL, Doey L, Lowe J, et al. (1997) Prion protein immunocytochemistry-UK Five Centre Consensus Report. Neuropathol Appl Neurobiol 23:26-35
3. Brown KL, Ritchie DL, McBride PA, Bruce ME (2000) Detection of PrP in extraneural tissues. Microsc Res Tech 50:40-45
4. Bruce ME, McBride PA, Farquhar CF (1989) Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie. Neurosci Lett 102:1-6
5. DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB (1987) Changes in the localization of brain prion proteins during scrapie infection. Neurology 37:1271-1280
6. Farquhar CF, Somerville RA, Ritchie LA (1989) Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy. J Virol Methods 24:215-221
7. Franklin KBJ, Paxinos G (1997) The Mouse Brain in Stereotaxic Co-ordinates. San Diego, Academic Press
8. Haritani M, Spencer YI, Wells GAH (1994) Hydrated autoclave pretreatment enhancement of prion protein immunoreactivity in formalin-fixed bovine spongiform encephalopathy-affected brain. Acta Neuropathol (Berl) 87:86-90
9. Jamieson E, Jeffrey M, Ironside JW, Fraser JR (2001) Apoptosis and dendritic dysfunction precede prion protein accumulation in 87V scrapie. Neuroreport 12:2147-2153
10. Jeffrey M, Goodsir CM, Bruce M, McBride PA, Scott JR, Halliday WG (1994) Correlative light and electron-microscopy studies of PrP localization in 87V scrapie. Brain Res 656:329-343
11. Jeffrey M, Halliday WG, Bell J, Johnston AR, Macleod NK, Ingham C, Sayers AR, et al. (2000) Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus. Neuropathol Appl Neurobiol 26:41-54
12. res in murine ME7 scrapie in relation to pathological and PrP immunohistochemical changes. J Comp Pathol 124:20-28
13. Kitamoto T, Ogomori K, Tateishi J, Prusiner SB (1987) Formic acid pre-treatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest 57:230-236
14. Kretzschmar HA, Ironside JW, Dearmond SJ, Tateishi J (1996) Diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Arch Neurol 53:913-920
15. Langeveld JPM, Farquhar CF, Pocchiari M, Birkett C, Bostock C, Meloen RH (1993) Antigenic sites of bovine prion protein. In Bradley R, Marchant B, eds. Transmissible Spongiform Encephalopathies. Proceedings of a Consultation on BSE. Brussels, Commission of the European Communities 315-321
16. Li R, Liu T, Wong B-S, Pan T, Morillas M, Swietnicki W, O'Rourke K, et al. (2000) Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus. J Mol Biol 301:567-573
17. Liu T, Zwingman T, Li R, Pan T, Wong B-S, Petersen RB, Gambetti P, et al. (2001) Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies. Brain Res 896:118-129
18. McBride PA, Eikelenboom P, Kraal G, Fraser H, Bruce ME (1992) PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice. J Pathol 168:413-418
19. McBride PA, Schulz-Schaeffer WJ, Donaldson M, Bruce M, Diringer H, Kretzschmar HA, Beekes M (2001) Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves. J Virol 75:9320-9327
20. McBride PA, Wilson MI, Eikelenboom P, Tunstall A, Bruce ME (1998) Heparan sulfate proteoglycan is associated with amyloid plaques and neuroanatomically targeted PrP pathology throughout the incubation period of scrapie-infected mice. Exp Neurol 149:447-454
21. McLean CA, Ironside JW, Alpers MP, Brown PW, Cervenakova L, Anderson RM, Masters CL (1998) Comparative neuropathology of kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype of host. Brain Pathol 8:429-437
22. McLean IW, Nakane PK (1974) Periodate-lysine-paraformaldehyde fixative. A new fixative for immunoelectron microscopy. J Histochem Cytochem 22:1077-1083
23. O'Rourke KI, Baszler TV, Besser TE, Miller JM, Cutlip RC, Wells GAH, Ryder SJ, et al. (2000) Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue. J Clin Microbiol 38:3254-3259
24. Scott JR, Fraser H (1984) Degenerative hippocampal pathology in mice infected with scrapie. Acta Neuropathol (Berl) 65:62-68
25. Somerville (1999) Host and transmissible spongiform encephalopathy agent strain control glycosylation of PrP. J Gen Virol 80:1865-1872
26. Wolfe LL, Conner MM, Baker TH, Dreitz VJ, Burnham KP, Williams ES, Hobbs NT, et al. (2002) Evaluation of antemortem sampling to estimate chronic wasting disease prevalence in free-ranging mule deer. J Wildl Manage 66:564-573