The role of drug metabolism in new drug development

Yaoxue Xuebao

Volumn 35, Issue 2, 2000, Pages 156-160

  Zhao, Dongmei ^a   Li, Yan ^a   Lu, Yehong ^a  

^a NONE

Author keywords

Drug design; Drug metabolism; New drug development; Safety and side effect

Indexed keywords

EID: 0041723098     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Obach RS, Baxter JG, Liston TE, et al. J Pharmacol Exp Ther, 1997, 283:46
2. Lin JH, Anthony YH Lu. Pharmacol Rev, 1997, 49:403
3. Lin JH, Duggan DE, Chen IW, et al. Drug Metab Dispos, 1991, 19:926
4. Feldman PL, James MK, Brackeen MF, et al. J Med Chem, 1991, 34:2202
5. Jensen CB, Jollow DJ. Toxicol Appl Pharmacol, 1991, 111:1
6. Paul D, Standifer KM, Inturrisi CE, et al. J Pharmacol Exp Ther, 1989, 251:477
7. Rodrigues AD. Pharm Res, 1997, 14:1504
8. Yun CH, Okerholm RA, Guengerich FP. Drug Metab Dispos, 1993, 21:403
9. Lemoine A, Gautier JC, Azoulay D, et al. Mol Pharmacol, 1993, 43:827
10. Yasumori T, Chen L, Nagata K, et al. J Pharmacol Exp Ther, 1993, 264:89
11. Dogterom P, Rothuizen J. Drug Metab Dispos, 1993, 21: 705
12. Lin JH, Anthony YH Lu. Clin Pharmacokinet, 1998, 35 :361
13. Nelson DR, Koymans L, Kamataki T, et al. Pharmacogenetics, 1996, 6:1
14. Stearns RA, Miller RR, Doss GA, et al. Drug Metab Dispos, 1992, 20:281
15. Kunze KL, Wienkers LC, Thummel KE, et al. Drug Metab Dispos, 1996, 24:414
16. Ronald EW. Drug Metab Dispos, 1998, 26:1213
17. Parkinson A. Toxicol Pathol, 1996, 24:45
18. Alexander J, Wallin H, Rossland OJ, et al. Carcinogenesis, 1991, 12:2239
19. Wrighton SA, Ring BJ. Pharm Res, 1994, 11:921
20. Siddoway LA, Thompson KA, McAllister CB, et al. Circulation, 1987, 75:785
21. Szklarz GD, Halpert JR. Drug Metab Dispos, 1998, 26: 1179
22. Kuhlmann J. Int J Clin Pharmacol Ther, 1997, 35:541