RPE cell transplants to non-immune-privileged sites of the eye transform into fibroblast-like cells

Current Eye Research

Volumn 27, Issue 1, 2003, Pages 25-34

  Knoernschild, Tina ^a   Grasbon, Thomas ^b   Wilsch, Caren ^a   Kampik, Anselm ^b   Lütjen Drecoll, Elke ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Adult tissue transplantation *immunology; Animal; Graft survival physiology; Inbred mice; Pigment epithelium of eye *immunology *transplantation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASOLATERAL MEMBRANE; CELL COMPARTMENTALIZATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; EPIRETINAL MEMBRANE; EPITHELIUM CELL; FIBROBLAST; GRAFT SURVIVAL; IMMUNOLOGY; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SPINDLE CELL; SUBRETINAL NEOVASCULARIZATION; TISSUE TRANSPLANTATION; VITREORETINOPATHY;

ANIMALS; CELL DIFFERENTIATION; CELL TRANSPLANTATION; CHOROID; CONJUNCTIVA; FIBROBLASTS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON; PIGMENT EPITHELIUM OF EYE; RETINA; RETINAL DEGENERATION; TRANSPLANTATION TOLERANCE; TRANSPLANTATION, HETEROTOPIC; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC; VITREOUS BODY;

EID: 0041704875     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.27.2.25.15453     Document Type: Article

References (29)

1. Machemer R, Laqua H. Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation). Am J Ophthalmol. 1975;80:1-23.
2. Smith RS, Van Heuven WA, Streeten B. Vitreous membranes: A light and electron microscopical study. Arch Ophthalmol. 1976;94:1556-1560.
3. Machemer R. Pathogenesis and classification of massive periretinal proliferation. Br J Ophthalmol. 1978;62:737-747.
4. Machemer R, van Horn D, Aaberg TM. Pigment epithelial proliferation in human retinal detachment with massive periretinal proliferation. Am J Ophthalmol. 1978;85:181-191.
5. Wallow IH, Miller SA. Preretinal membrane by retinal pigment epithelium. Arch Ophthalmol. 1978;96:1643-1646.
6. Green WR, Kenyon KR, Michels RG et al. Ultrastructure of epiretinal membranes causing macular pucker after retinal re-attachment surgery. Trans Ophthalmol Soc UK. 1979;99:65-77.
7. Kampik A, Kenyon KR, Michels RG et al. Epiretinal and vitreous membranes. Comparative study of 56 cases. Arch Ophthalmol. 1981;99:1445-1454.
8. Radtke ND, Tano Y, Chandler D et al. Simulation of massive periretinal proliferation by autotransplantation of retinal pigment epithelial cells in rabbits. Am J Ophthalmol. 1981;91:76-87.
9. Flood MT, Gouras P, Kjeldbye H. Growth characteristics and ultrastructure of human retinal pigment epithelium in vitro. Invest Ophthalmol Vis Sci. 1980;19:1309-1320.
10. Kim KS, Tezel TH, Del Priore LV. Minimum number of adult human retinal pigment epithelial cells required to establish a confluent monolayer in vitro. Curr Eye Res. 1998;17:962-969.
11. Casaroli-Marano RP, Pagan R, Vilaro S. Epithelial-mesenchymal transition in proliferative vitreoretinopathy: Intermediate filament protein expression in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1999;40:2062-2072.
12. Uebersax ED, Grindstaff RD, Defoe DM. Survival of the retinal pigment epithelium in vitro: Comparison of freshly isolated and subcultured cells. Exp Eye Res. 2000;70:381-390.
13. Grisanti S, Ishioka M, Kosiewicz M et al. Immunity and immune privilege elicited by cultured retinal pigment epithelial cell transplants. Invest Ophthalmol Vis Sci. 1997;38:1619-1626.
14. Streilein JW, Ma N, Wenkel H et al. Immunobiology and privilege of neuronal retina and pigment epithelium transplants. Vision Res. 2002;42:487-495.
15. Streilein JW. Limitations in the study of immune privilege in the subretinal space of the rodent. Invest Ophthalmol Vis Sci. 1999;40:3069.
16. Al-Amro S, Tang L, Kaplan HJ. Limitations in the study of immune privilege in the subretinal space of the rodent. Invest Ophthalmol Vis Sci. 1999;40:3067-3069.
17. Jiang LQ, Jorquera M, Streilein JW. Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. Invest Ophthalmol Vis Sci. 1993;34:3347-3354.
18. Zhang X, Bok D. Transplantation of retinal pigment epithelial cells and immune response in the subretinal space [see comments]. Invest Ophthalmol Vis Sci. 1998;39:1021-1027.
19. Wenkel H, Streilein JW. Evidence that retinal pigment epithelium functions as an immune-privileged tissue. Invest Ophthalmol Vis Sci. 2000;41:3467-3473.
20. Lutjen-Drecoll E, Bergstrom A, Ehinger B. Ultrastructure of retinal cells transplanted to the rabbit choroid. Ophthalmologica. 2000;214:70-77.
21. Ghosh F, Ehinger B. Full-thickness retinal transplants: A review. Ophthalmologica. 2000;214:54-69.
22. Jiang LQ, Jorquera M, Streilein JW. Immunologic consequences of intraocular implantation of retinal pigment epithelial allografts. Exp Eye Res. 1994;58:719-728.
23. Welge-Lüssen U, Wilsch C, Neuhardt T et al. Loss of anterior chamber-associated immune deviation (ACAID) in aged retinal degeneration (rd) mice [In Process Citation]. Invest Ophthalmol Vis Sci. 1999;40:3209-3214.
24. Ito S, Karnovsky MJ. Formaldehyde-glutaraldehyde fixatives containing trinitro compounds. J Cell Biol. 1968;39:168-169.
25. Campochiaro PA. Cytokine production by retinal pigmented epithelial cells. Int Rev Cytol. 1993;146:75-82.
26. Campochiaro PA. Pathogenic mechanisms in proliferative vitreoretinopathy. Arch Ophthalmol. 1997;115:237-241.
27. Bynoe LA, Chang TS, Funata M et al. Histopathologic examination of vascular patterns in subfoveal neovascular membranes. Ophthalmology. 1994;101:1112-1117.
28. Chang TS, Freund KB, de la Cruz Z et al. Clinicopathologic correlation of choroidal neovascularization demonstrated by indocyanine green angiography in a patient with retention of good vision for almost four years. Retina. 1994;14:114-124.
29. el Baba F, Jarrett WH, 2nd, Harbin TS, Jr et al. Massive hemorrhage complicating age-related macular degeneration. Clinicopathologic correlation and role of anticoagulants. Ophthalmology. 1986;93:1581-1.592.