메뉴 건너뛰기




Volumn 25, Issue 7, 2003, Pages 1952-1974

Tegaserod maleate in the treatment of irritable bowel syndrome: A clinical review

Author keywords

Constipation; Irritable bowel syndrome; Tegaserod maleate

Indexed keywords

ANTIDEPRESSANT AGENT; BENZAMIDE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CISAPRIDE; DEXTROMETHORPHAN; DICYCLOVERINE; DIGOXIN; ETHINYLESTRADIOL PLUS LEVONORGESTREL; HYOSCYAMINE; ISPAGULA; METHYLCELLULOSE; PLACEBO; POLYCARBOPHIL CALCIUM; SEROTONIN 4 AGONIST; SEROTONIN UPTAKE INHIBITOR; SPASMOLYTIC AGENT; TEGASEROD; THEOPHYLLINE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 0041701536     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(03)80198-4     Document Type: Article
Times cited : (32)

References (91)
  • 1
    • 0029024716 scopus 로고
    • Irritable bowel syndrome in a community: Symptom subgroups, risk factors, and health care utilization
    • Talley NJ, Zinsmeister AR, Melton LJ III. Irritable bowel syndrome in a community: Symptom subgroups, risk factors, and health care utilization. Am J Epidemiol. 1995;142:76-83.
    • (1995) Am J Epidemiol , vol.142 , pp. 76-83
    • Talley, N.J.1    Zinsmeister, A.R.2    Melton L.J. III3
  • 2
    • 0038161823 scopus 로고    scopus 로고
    • Extra-intestinal symptoms in patients with irritable bowel syndrome (IBS)
    • Abstract
    • Zaman M, Chavez N, Krueger R, et al. Extra-intestinal symptoms in patients with irritable bowel syndrome (IBS). Gastroenterology. 2001;120:A636. Abstract.
    • (2001) Gastroenterology , vol.120
    • Zaman, M.1    Chavez, N.2    Krueger, R.3
  • 3
    • 0035109696 scopus 로고    scopus 로고
    • Management of the irritable bowel syndrome
    • Camilleri M. Management of the irritable bowel syndrome. Gastroenterology. 2001;120:652-668.
    • (2001) Gastroenterology , vol.120 , pp. 652-668
    • Camilleri, M.1
  • 4
    • 3042581462 scopus 로고    scopus 로고
    • Evidence-based position statement on the management of irritable bowel syndrome in North America
    • Evidence-based position statement on the management of irritable bowel syndrome in North America. Am J Gastroenterol. 2002;97(Suppl 11):S1-S5.
    • (2002) Am J Gastroenterol , vol.97 , Issue.11 SUPPL.
  • 5
    • 0035859198 scopus 로고    scopus 로고
    • The irritable bowel syndrome
    • Horwitz BJ, Fisher RS. The irritable bowel syndrome. N Engl J Med. 2001;344:1846-1850.
    • (2001) N Engl J Med , vol.344 , pp. 1846-1850
    • Horwitz, B.J.1    Fisher, R.S.2
  • 6
    • 0036234316 scopus 로고    scopus 로고
    • The burden of selected digestive diseases in the United States
    • Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology. 2002;122:1500-1511.
    • (2002) Gastroenterology , vol.122 , pp. 1500-1511
    • Sandler, R.S.1    Everhart, J.E.2    Donowitz, M.3
  • 8
    • 0036081004 scopus 로고    scopus 로고
    • The economic impact of irritable bowel syndrome in a managed care setting
    • Patel RP, Petitta A, Fogel R, et al. The economic impact of irritable bowel syndrome in a managed care setting. J Clin Gastroenterol. 2002;35:14-20.
    • (2002) J Clin Gastroenterol , vol.35 , pp. 14-20
    • Patel, R.P.1    Petitta, A.2    Fogel, R.3
  • 9
    • 0042307885 scopus 로고    scopus 로고
    • Economic outcomes of irritable bowel syndrome: An employer perspective
    • Abstract
    • Leong S, Barghout V, Birnbaum H, et al. Economic outcomes of irritable bowel syndrome: An employer perspective. Am J Gastroenterol. 2001;96:S320. Abstract.
    • (2001) Am J Gastroenterol , vol.96
    • Leong, S.1    Barghout, V.2    Birnbaum, H.3
  • 11
    • 0002340025 scopus 로고    scopus 로고
    • Rome II: A multinational consensus document on functional gastrointestinal disorders
    • Drossman D, Corazziari E, Talley N, et al. Rome II: A multinational consensus document on functional gastrointestinal disorders. Gut. 1999;45:1-81.
    • (1999) Gut , vol.45 , pp. 1-81
    • Drossman, D.1    Corazziari, E.2    Talley, N.3
  • 12
    • 85059110443 scopus 로고    scopus 로고
    • Reclassification of functional bowel disorders with Rome II diagnostic criteria
    • Abstract
    • Badiali D, Altobelli G, Corazziari E. Reclassification of functional bowel disorders with Rome II diagnostic criteria. Gastroenterology. 2001;120:A755. Abstract.
    • (2001) Gastroenterology , vol.120
    • Badiali, D.1    Altobelli, G.2    Corazziari, E.3
  • 13
    • 0035057423 scopus 로고    scopus 로고
    • Irritable bowel syndrome: New agents targeting serotonin receptor subtypes
    • De Ponti F, Tonini M. Irritable bowel syndrome: New agents targeting serotonin receptor subtypes. Drugs. 2001;61:317-332.
    • (2001) Drugs , vol.61 , pp. 317-332
    • De Ponti, F.1    Tonini, M.2
  • 14
    • 0036829091 scopus 로고    scopus 로고
    • Gender differences in irritable bowel syndrome
    • Chang L, Heitkemper MM. Gender differences in irritable bowel syndrome. Gastroenterology. 2002;123:1686-1701.
    • (2002) Gastroenterology , vol.123 , pp. 1686-1701
    • Chang, L.1    Heitkemper, M.M.2
  • 15
    • 0026047760 scopus 로고
    • Effect of eating on colonic motility and transit in patients with functional diarrhea. Simultaneous scintigraphic and manometric evaluations
    • Bazzocchi G, Ellis J, Villanueva-Meyer J, et al. Effect of eating on colonic motility and transit in patients with functional diarrhea. Simultaneous scintigraphic and manometric evaluations. Gastroenterology. 1991;101:1298-1306.
    • (1991) Gastroenterology , vol.101 , pp. 1298-1306
    • Bazzocchi, G.1    Ellis, J.2    Villanueva-Meyer, J.3
  • 16
    • 0025019710 scopus 로고
    • Postprandial colonic transit and motor activity in chronic constipation
    • Bazzocchi G, Ellis J, Villanueva-Meyer J, et al. Postprandial colonic transit and motor activity in chronic constipation. Gastroenterology. 1990;98:686-693.
    • (1990) Gastroenterology , vol.98 , pp. 686-693
    • Bazzocchi, G.1    Ellis, J.2    Villanueva-Meyer, J.3
  • 17
    • 0020560879 scopus 로고
    • Irritable bowel syndrome: Relationship of disorders in the transit of a single solid meal to symptom patterns
    • Cann PA, Read NW, Brown C, et al. Irritable bowel syndrome: Relationship of disorders in the transit of a single solid meal to symptom patterns. Gut. 1983;24:405-411.
    • (1983) Gut , vol.24 , pp. 405-411
    • Cann, P.A.1    Read, N.W.2    Brown, C.3
  • 18
    • 0026542908 scopus 로고
    • Transit through the proximal colon influences stool weight in the irritable bowel syndrome
    • Vassallo M, Camilleri M, Phillips SF, et al. Transit through the proximal colon influences stool weight in the irritable bowel syndrome. Gastroenterology. 1992;102:102-108.
    • (1992) Gastroenterology , vol.102 , pp. 102-108
    • Vassallo, M.1    Camilleri, M.2    Phillips, S.F.3
  • 19
    • 0025893393 scopus 로고
    • Scintigraphic measurement of regional gut transit in idiopathic constipation
    • Stivland T, Camilleri M, Vassallo M, et al. Scintigraphic measurement of regional gut transit in idiopathic constipation. Gastroenterology. 1991;101:107-115.
    • (1991) Gastroenterology , vol.101 , pp. 107-115
    • Stivland, T.1    Camilleri, M.2    Vassallo, M.3
  • 20
    • 0025271210 scopus 로고
    • Anorectal manometry in irritable bowel syndrome: Differences between diarrhoea and constipation predominant subjects
    • Prior A, Maxton DG, Whorwell PJ. Anorectal manometry in irritable bowel syndrome: Differences between diarrhoea and constipation predominant subjects. Gut. 1990;31:458-462.
    • (1990) Gut , vol.31 , pp. 458-462
    • Prior, A.1    Maxton, D.G.2    Whorwell, P.J.3
  • 21
    • 0027329920 scopus 로고
    • 3-antagonist (ondansetron) on rectal sensitivity and compliance in health and the irritable bowel syndrome
    • 3-antagonist (ondansetron) on rectal sensitivity and compliance in health and the irritable bowel syndrome. Aliment Pharmacol Ther. 1993;7:543-551.
    • (1993) Aliment Pharmacol Ther , vol.7 , pp. 543-551
    • Hammer, J.1    Phillips, S.F.2    Talley, N.J.3    Camilleri, M.4
  • 22
    • 0026695825 scopus 로고
    • Colonic tone and motility in patients with irritable bowel syndrome
    • Vassallo MJ, Camilleri M, Phillips SF, et al. Colonic tone and motility in patients with irritable bowel syndrome. Mayo Clin Proc. 1992;67:725-731.
    • (1992) Mayo Clin Proc , vol.67 , pp. 725-731
    • Vassallo, M.J.1    Camilleri, M.2    Phillips, S.F.3
  • 23
    • 0023234469 scopus 로고
    • Altered small bowel motility in irritable bowel syndrome is correlated with symptoms
    • Kellow JE, Phillips SF. Altered small bowel motility in irritable bowel syndrome is correlated with symptoms. Gastroenterology. 1987;92:1885-1893.
    • (1987) Gastroenterology , vol.92 , pp. 1885-1893
    • Kellow, J.E.1    Phillips, S.F.2
  • 24
    • 0028205275 scopus 로고
    • Ambulatory small intestinal motility in 'diarrhoea' predominant irritable bowel syndrome
    • Gorard DA, Libby GW, Farthing MJ. Ambulatory small intestinal motility in 'diarrhoea' predominant irritable bowel syndrome. Gut. 1994;35:203-210.
    • (1994) Gut , vol.35 , pp. 203-210
    • Gorard, D.A.1    Libby, G.W.2    Farthing, M.J.3
  • 25
    • 0029950915 scopus 로고    scopus 로고
    • Ambulatory 24-hour jejunal motility in diarrhea-predominant irritable bowel syndrome
    • Schmidt T, Hackelsberger N, Widmer R, et al. Ambulatory 24-hour jejunal motility in diarrhea-predominant irritable bowel syndrome. Scand J Gastroenterol. 1996;31:581-589.
    • (1996) Scand J Gastroenterol , vol.31 , pp. 581-589
    • Schmidt, T.1    Hackelsberger, N.2    Widmer, R.3
  • 26
    • 0030063571 scopus 로고    scopus 로고
    • Jejunal sensorimotor dysfunction in irritable bowel syndrome: Clinical and psychosocial features
    • Evans PR, Bennett EJ, Bak YT, et al. Jejunal sensorimotor dysfunction in irritable bowel syndrome: Clinical and psychosocial features. Gastroenterology. 1996;110:393-404.
    • (1996) Gastroenterology , vol.110 , pp. 393-404
    • Evans, P.R.1    Bennett, E.J.2    Bak, Y.T.3
  • 27
    • 0024326058 scopus 로고
    • Motility disorders and stress
    • Camilleri M, Neri M. Motility disorders and stress. Dig Dis Sci. 1989;34:1777-1786.
    • (1989) Dig Dis Sci , vol.34 , pp. 1777-1786
    • Camilleri, M.1    Neri, M.2
  • 28
    • 0015581604 scopus 로고
    • Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome
    • Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut. 1973;14:125-132.
    • (1973) Gut , vol.14 , pp. 125-132
    • Ritchie, J.1
  • 29
    • 0029022779 scopus 로고
    • Altered rectal perception is a biological marker of patients with irritable bowel syndrome
    • Mertz H, Naliboff B, Munakata J, et al. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology. 1995;109:40-52.
    • (1995) Gastroenterology , vol.109 , pp. 40-52
    • Mertz, H.1    Naliboff, B.2    Munakata, J.3
  • 30
    • 0030859166 scopus 로고    scopus 로고
    • Sigmoid afferent mechanisms in patients with irritable bowel syndrome
    • Lembo T, Munakata J, Naliboff B, et al. Sigmoid afferent mechanisms in patients with irritable bowel syndrome. Dig Dis Sci. 1997;42:1112-1120.
    • (1997) Dig Dis Sci , vol.42 , pp. 1112-1120
    • Lembo, T.1    Munakata, J.2    Naliboff, B.3
  • 31
    • 0033986140 scopus 로고    scopus 로고
    • Correlation of symptom criteria with perception thresholds during rectosigmoid distension in irritable bowel syndrome patients
    • Schmulson M, Chang L, Naliboff B, et al. Correlation of symptom criteria with perception thresholds during rectosigmoid distension in irritable bowel syndrome patients. Am J Gastroenterol. 2000;95:152-156.
    • (2000) Am J Gastroenterol , vol.95 , pp. 152-156
    • Schmulson, M.1    Chang, L.2    Naliboff, B.3
  • 32
    • 0034926870 scopus 로고    scopus 로고
    • The role of serotonin in the pathophysiology of irritable bowel syndrome
    • Crowell MD. The role of serotonin in the pathophysiology of irritable bowel syndrome. Am J Manag Care. 2001;7(Suppl 8):S252-S260.
    • (2001) Am J Manag Care , vol.7 , Issue.8 SUPPL.
    • Crowell, M.D.1
  • 33
    • 4244099468 scopus 로고    scopus 로고
    • c-fos Protein expression in the brain of the anesthetized rat induced by colorectal distention
    • Abstract
    • Wrzos H, Guillaume M, Norgren R, et al. c-fos Protein expression in the brain of the anesthetized rat induced by colorectal distention. Gastroenterology. 2001;120:A715. Abstract.
    • (2001) Gastroenterology , vol.120
    • Wrzos, H.1    Guillaume, M.2    Norgren, R.3
  • 34
    • 0034066325 scopus 로고    scopus 로고
    • The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat
    • Kozlowski CM, Green A, Grundy D, et al. The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat. Gut. 2000;46:474-480.
    • (2000) Gut , vol.46 , pp. 474-480
    • Kozlowski, C.M.1    Green, A.2    Grundy, D.3
  • 35
    • 85059110369 scopus 로고    scopus 로고
    • Is psychiatric illness, personality or both a predictor of IBS in young adults? Results from a birth cohort study in New Zealand
    • Abstract
    • Howell S, Poulton R, Talley N. Is psychiatric illness, personality or both a predictor of IBS in young adults? Results from a birth cohort study in New Zealand. Gastroenterology. 2001;120:A114. Abstract.
    • (2001) Gastroenterology , vol.120
    • Howell, S.1    Poulton, R.2    Talley, N.3
  • 36
    • 0001866072 scopus 로고    scopus 로고
    • Psychological stress increases visceral sensitivity in patients with irritable bowel syndrome (IBS) but not controls
    • Abstract
    • Dickhaus B, Firooz N, Stains J, et al. Psychological stress increases visceral sensitivity in patients with irritable bowel syndrome (IBS) but not controls. Gastroenterology. 2001;120:A67. Abstract.
    • (2001) Gastroenterology , vol.120
    • Dickhaus, B.1    Firooz, N.2    Stains, J.3
  • 37
    • 85059110086 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide levels are elevated in the blood plasma of irritable bowel syndrome (IBS) patients
    • Abstract
    • Palsson O, Turner M, Davies M, et al. Vasoactive intestinal peptide levels are elevated in the blood plasma of irritable bowel syndrome (IBS) patients. Gastroenterology. 2001;120:A718. Abstract.
    • (2001) Gastroenterology , vol.120
    • Palsson, O.1    Turner, M.2    Davies, M.3
  • 38
    • 0031980886 scopus 로고    scopus 로고
    • Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study
    • Bearcroft CP, Perrett D, Farthing MJ. Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study. Gut. 1998;42:42-46.
    • (1998) Gut , vol.42 , pp. 42-46
    • Bearcroft, C.P.1    Perrett, D.2    Farthing, M.J.3
  • 39
    • 0000021676 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine and enterochromaffin cells in the irritable bowel syndrome
    • Abstract
    • Bose M, Nickols C, Feakins R, Farthing M. 5-Hydroxytryptamine and enterochromaffin cells in the irritable bowel syndrome. Gastroenterology. 2000;118:A563. Abstract.
    • (2000) Gastroenterology , vol.118
    • Bose, M.1    Nickols, C.2    Feakins, R.3    Farthing, M.4
  • 40
    • 0030068596 scopus 로고    scopus 로고
    • Psychometric scores and persistence of irritable bowel after infectious diarrhoea
    • Gwee KA, Graham JC, McKendrick MW, et al. Psychometric scores and persistence of irritable bowel after infectious diarrhoea. Lancet. 1996;347:150-153.
    • (1996) Lancet , vol.347 , pp. 150-153
    • Gwee, K.A.1    Graham, J.C.2    McKendrick, M.W.3
  • 41
    • 0033665517 scopus 로고    scopus 로고
    • Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome
    • Spiller R, Jenkins D, Thornley J, et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut. 2000;47:804-811.
    • (2000) Gut , vol.47 , pp. 804-811
    • Spiller, R.1    Jenkins, D.2    Thornley, J.3
  • 42
    • 25744445275 scopus 로고    scopus 로고
    • IBS patients exhibit subtle differences in the composition of the residual colonic inflammatory infiltrate
    • Abstract
    • Hollerbach S, Kizil F, Reiser M, et al. IBS patients exhibit subtle differences in the composition of the residual colonic inflammatory infiltrate. Gastroenterology. 2002;122:A319. Abstract.
    • (2002) Gastroenterology , vol.122
    • Hollerbach, S.1    Kizil, F.2    Reiser, M.3
  • 43
    • 0033608354 scopus 로고    scopus 로고
    • Increased risk of irritable bowel syndrome after bacterial gastroenteritis: Cohort study
    • Rodriguez LA, Ruigomez A. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: Cohort study. BMJ. 1999;318:565-566.
    • (1999) BMJ , vol.318 , pp. 565-566
    • Rodriguez, L.A.1    Ruigomez, A.2
  • 44
    • 0027964714 scopus 로고
    • Irritable bowel syndrome - Post Salmonella infection
    • McKendrick MW, Read NW. Irritable bowel syndrome - post Salmonella infection. J Infect. 1994;29:1-3.
    • (1994) J Infect , vol.29 , pp. 1-3
    • McKendrick, M.W.1    Read, N.W.2
  • 45
    • 0036716739 scopus 로고    scopus 로고
    • Prognosis in post-infective irritable bowel syndrome: A six year follow up study
    • Neal KR, Barker L, Spiller RC. Prognosis in post-infective irritable bowel syndrome: A six year follow up study. Gut. 2002;51:410-413.
    • (2002) Gut , vol.51 , pp. 410-413
    • Neal, K.R.1    Barker, L.2    Spiller, R.C.3
  • 46
    • 0034666393 scopus 로고    scopus 로고
    • Oral serotonin type 3-receptor antagonists for prevention of chemotherapy-induced emesis
    • Lindley C, Blower P. Oral serotonin type 3-receptor antagonists for prevention of chemotherapy-induced emesis. Am J Health Syst Pharm. 2000;57:1685-1697.
    • (2000) Am J Health Syst Pharm , vol.57 , pp. 1685-1697
    • Lindley, C.1    Blower, P.2
  • 47
    • 0026735031 scopus 로고
    • 3 receptors mediate cisplatin-induced emesis in dogs
    • 3 receptors mediate cisplatin-induced emesis in dogs. Jpn J Pharmacol. 1992;59:221-226.
    • (1992) Jpn J Pharmacol , vol.59 , pp. 221-226
    • Fukui, H.1    Yamamoto, M.2    Sato, S.3
  • 49
    • 0024477741 scopus 로고
    • 3 Receptor antagonists injected into the area postrema inhibit cisplatin-induced emesis in the ferret
    • 3 Receptor antagonists injected into the area postrema inhibit cisplatin-induced emesis in the ferret. Br J Pharmacol. 1989;97:247-255.
    • (1989) Br J Pharmacol , vol.97 , pp. 247-255
    • Higgins, G.A.1    Kilpatrick, G.J.2    Bunce, K.T.3
  • 50
    • 0001787087 scopus 로고    scopus 로고
    • 4 receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat
    • Abstract
    • 4 receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat. Gastroenterology. 2001;120:A6. Abstract.
    • (2001) Gastroenterology , vol.120
    • Hicks, G.1    Clayton, N.2    Kirkup, A.3
  • 51
    • 0005469245 scopus 로고    scopus 로고
    • 4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects
    • Abstract
    • 4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects. Gastroenterology. 2002;122:A311. Abstract.
    • (2002) Gastroenterology , vol.122
    • Coffin, B.1    Farmachidi, J.2    Bastie, A.3
  • 52
    • 0036743090 scopus 로고    scopus 로고
    • A new look at irritable bowel syndrome (IBS): A neuroenteric disorder
    • Frissora CL. A new look at irritable bowel syndrome (IBS): A neuroenteric disorder. Compr Ther. 2002;28:222-231.
    • (2002) Compr Ther , vol.28 , pp. 222-231
    • Frissora, C.L.1
  • 53
    • 0021272930 scopus 로고
    • What is the benefit of coarse wheat bran in patients with irritable bowel syndrome?
    • Cann PA, Read NW, Holdsworth CD. What is the benefit of coarse wheat bran in patients with irritable bowel syndrome? Gut. 1984;25:168-173.
    • (1984) Gut , vol.25 , pp. 168-173
    • Cann, P.A.1    Read, N.W.2    Holdsworth, C.D.3
  • 54
    • 0031022542 scopus 로고    scopus 로고
    • Clinical response to dietary fiber treatment of chronic constipation
    • Voderholzer WA, Schatke W, Muhldorfer BE, et al. Clinical response to dietary fiber treatment of chronic constipation. Am J Gastroenterol. 1997;92:95-98.
    • (1997) Am J Gastroenterol , vol.92 , pp. 95-98
    • Voderholzer, W.A.1    Schatke, W.2    Muhldorfer, B.E.3
  • 55
    • 0028097382 scopus 로고
    • Meta-analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome
    • Poynard T, Naveau S, Mory B, Chaput JC. Meta-analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther. 1994;8:499-510.
    • (1994) Aliment Pharmacol Ther , vol.8 , pp. 499-510
    • Poynard, T.1    Naveau, S.2    Mory, B.3    Chaput, J.C.4
  • 56
    • 0001103799 scopus 로고
    • The properties of a new prokinetically active drug, SDZ HTF 919
    • Abstract
    • Pfannkuche HJ, Buhl T, Gamse R, Hoyer D, et al. The properties of a new prokinetically active drug, SDZ HTF 919. Neurogastroenterol Motil. 1995;7:280. Abstract.
    • (1995) Neurogastroenterol Motil , vol.7 , pp. 280
    • Pfannkuche, H.J.1    Buhl, T.2    Gamse, R.3    Hoyer, D.4
  • 57
    • 0036035301 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity
    • Appel-Dingemanse S. Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity. Clin Pharmacokinet. 2002;41:1021-1042.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 1021-1042
    • Appel-Dingemanse, S.1
  • 59
    • 0031595212 scopus 로고    scopus 로고
    • 4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine
    • 4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine. Gastroenterology. 1998;115:370-380.
    • (1998) Gastroenterology , vol.115 , pp. 370-380
    • Grider, J.R.1    Foxx-Orenstein, A.E.2    Jin, J.G.3
  • 61
    • 0033345899 scopus 로고    scopus 로고
    • Effect of meal timing not critical for the pharmacokinetics of tegaserod (HTF 919)
    • Zhou H, Khalilieh S, Lau H, et al. Effect of meal timing not critical for the pharmacokinetics of tegaserod (HTF 919). J Clin Pharmacol. 1999;39:911-919.
    • (1999) J Clin Pharmacol , vol.39 , pp. 911-919
    • Zhou, H.1    Khalilieh, S.2    Lau, H.3
  • 62
    • 0000585343 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of SDZ HTF 919, a new promotile drug, in healthy subjects and in patients with hepatic cirrhosis
    • Abstract
    • Appel-Dingemanse S, Hubert M, Alladina L, et al. Pharmacokinetics and safety of SDZ HTF 919, a new promotile drug, in healthy subjects and in patients with hepatic cirrhosis. Digestion. 1998;59:736. Abstract.
    • (1998) Digestion , vol.59 , pp. 736
    • Appel-Dingemanse, S.1    Hubert, M.2    Alladina, L.3
  • 63
    • 33749113374 scopus 로고    scopus 로고
    • Pharmacokinetics of SDZ HTF 919 not altered in subjects with severe renal insufficiency requiring hemodialysis
    • Abstract
    • Zhou H, McLeod J, Alladina L, et al. Pharmacokinetics of SDZ HTF 919 not altered in subjects with severe renal insufficiency requiring hemodialysis. Clin Pharmacol Ther. 1999;65:203. Abstract.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 203
    • Zhou, H.1    McLeod, J.2    Alladina, L.3
  • 64
    • 0034958807 scopus 로고    scopus 로고
    • The pharmacokinetics of the novel promotile drug, tegaserod, are similar in healthy subjects - Male and female, elderly and young
    • Appel-Dingemanse S, Horowitz A, Campestrini J, et al. The pharmacokinetics of the novel promotile drug, tegaserod, are similar in healthy subjects - male and female, elderly and young. Aliment Pharmacol Ther. 2001;15:937-944.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 937-944
    • Appel-Dingemanse, S.1    Horowitz, A.2    Campestrini, J.3
  • 65
    • 0004048238 scopus 로고    scopus 로고
    • East Hanover, NJ: Novartis Pharmaceuticals Corporation
    • Zelnorm™ [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2002.
    • (2002) Zelnorm™ [Package Insert]
  • 66
    • 0035123099 scopus 로고    scopus 로고
    • Review article: Tegaserod
    • Camilleri M. Review article: Tegaserod. Aliment Pharmacol Ther. 2001;15:277-289.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 277-289
    • Camilleri, M.1
  • 67
    • 0034821488 scopus 로고    scopus 로고
    • In vitro metabolism of tegaserod in human liver and intestine: Assessment of drug interactions
    • Vickers AE, Zollinger M, Dannecker R, et al. In vitro metabolism of tegaserod in human liver and intestine: Assessment of drug interactions. Drug Metab Dispos. 2001;29:1269-1276.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1269-1276
    • Vickers, A.E.1    Zollinger, M.2    Dannecker, R.3
  • 68
    • 0034873723 scopus 로고    scopus 로고
    • Tegaserod coadrninistration does not alter the pharmacokinetics of theophylline in healthy subjects
    • Zhou H, Khalilieh S, Svendsen K, et al. Tegaserod coadrninistration does not alter the pharmacokinetics of theophylline in healthy subjects. J Clin Pharmacol. 2001;41:987-993.
    • (2001) J Clin Pharmacol , vol.41 , pp. 987-993
    • Zhou, H.1    Khalilieh, S.2    Svendsen, K.3
  • 69
    • 0001300178 scopus 로고    scopus 로고
    • Tegaserod does not significantly affect the pharmacokinetics of dextromethorphan in healthy subjects
    • Abstract
    • Kalbag J, Migoya E, Osborn S, Lasseter K, et al. Tegaserod does not significantly affect the pharmacokinetics of dextromethorphan in healthy subjects. Gastroenterology. 2000;118 (Suppl 2):5422. Abstract.
    • (2000) Gastroenterology , vol.118 , Issue.2 SUPPL. , pp. 5422
    • Kalbag, J.1    Migoya, E.2    Osborn, S.3    Lasseter, K.4
  • 70
    • 0001300177 scopus 로고    scopus 로고
    • Tegaserod does not significantly affect the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
    • Abstract
    • Ledford PC, Ligueros-Saylan M, Campestrini J, Osborne S. Tegaserod does not significantly affect the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Gastroenterology. 2000;118:A1184. Abstract.
    • (2000) Gastroenterology , vol.118
    • Ledford, P.C.1    Ligueros-Saylan, M.2    Campestrini, J.3    Osborne, S.4
  • 71
    • 0001300176 scopus 로고    scopus 로고
    • Tegaserod (HTF919) does not decrease the effectiveness of an oral contraceptive when coadministered to healthy female subjects
    • Abstract
    • Zhou H, Walter Y, Hubert M, et al. Tegaserod (HTF919) does not decrease the effectiveness of an oral contraceptive when coadministered to healthy female subjects. Gastroenterology. 2000;118:A1207. Abstract.
    • (2000) Gastroenterology , vol.118
    • Zhou, H.1    Walter, Y.2    Hubert, M.3
  • 72
    • 0034829740 scopus 로고    scopus 로고
    • The effects of tegaserod (HTF 919) on the pharmacokinetics and pharmacodynamics of digoxin in healthy subjects
    • Zhou H, Horowitz A, Ledford PC, et al. The effects of tegaserod (HTF 919) on the pharmacokinetics and pharmacodynamics of digoxin in healthy subjects. J Clin Pharmacol. 2001;41:1131-1139.
    • (2001) J Clin Pharmacol , vol.41 , pp. 1131-1139
    • Zhou, H.1    Horowitz, A.2    Ledford, P.C.3
  • 73
    • 0030972047 scopus 로고    scopus 로고
    • SDZ HTF 919 stimulates canine colonic motility and transit in vivo
    • Nguyen A, Camilleri M, Kost LJ, et al. SDZ HTF 919 stimulates canine colonic motility and transit in vivo. J Pharmacol Exp Ther. 1997;280:1270-1276.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1270-1276
    • Nguyen, A.1    Camilleri, M.2    Kost, L.J.3
  • 74
    • 0033087906 scopus 로고    scopus 로고
    • Management of irritable bowel syndrome: Novel approaches to the pharmacology of gut motility
    • Scarpignato C, Pelosini I. Management of irritable bowel syndrome: Novel approaches to the pharmacology of gut motility. Can J Gastroenterol. 1999;13(Suppl A):50A-65A.
    • (1999) Can J Gastroenterol , vol.13 , Issue.SUPPL. A
    • Scarpignato, C.1    Pelosini, I.2
  • 75
    • 0034740722 scopus 로고    scopus 로고
    • 4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects
    • 4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects. Aliment Pharmacol Ther. 2001;15:1745-1751.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1745-1751
    • Degen, L.1    Matzinger, D.2    Merz, M.3
  • 76
    • 0034089045 scopus 로고    scopus 로고
    • Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome
    • Prather CM, Camilleri M, Zinsmeister AR, et al. Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome. Gastroenterology. 2000;118:463-468.
    • (2000) Gastroenterology , vol.118 , pp. 463-468
    • Prather, C.M.1    Camilleri, M.2    Zinsmeister, A.R.3
  • 77
    • 0036189032 scopus 로고    scopus 로고
    • Review article: The complexity of drug development for irritable bowel syndrome
    • Kamm MA. Review article: The complexity of drug development for irritable bowel syndrome. Aliment Pharmacol Ther. 2002;16:343-351.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 343-351
    • Kamm, M.A.1
  • 78
    • 0038136459 scopus 로고    scopus 로고
    • Persistent placebo response during a year-long controlled trial of IBS treatment
    • Abstract
    • Northcuff A, Mangel A, Hamm L, et al. Persistent placebo response during a year-long controlled trial of IBS treatment. Gastroenterology. 2001;120:A640. Abstract.
    • (2001) Gastroenterology , vol.120
    • Northcuff, A.1    Mangel, A.2    Hamm, L.3
  • 80
    • 0034794595 scopus 로고    scopus 로고
    • Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
    • Muller-Lissner SA, Fumagalli I, Bardhan KD, et al. Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation. Aliment Pharmacol Ther. 2001;15:1655-1666.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1655-1666
    • Muller-Lissner, S.A.1    Fumagalli, I.2    Bardhan, K.D.3
  • 81
    • 0001416435 scopus 로고    scopus 로고
    • 4 partial agonist tegaserod improves abdominal discomfort/pain and normalizes altered bowel function in irritable bowel syndrome
    • Abstract
    • 4 partial agonist tegaserod improves abdominal discomfort/pain and normalizes altered bowel function in irritable bowel syndrome. Am J Gastroenterol. 1999;94:A396. Abstract.
    • (1999) Am J Gastroenterol , vol.94
    • Lefkowitz, M.1    Shi, Y.2    Schmitt, C.3
  • 82
    • 0007692411 scopus 로고    scopus 로고
    • 4 agonist, improves abdominal bloating and altered stool consistency in irritable bowel syndrome (IBS)
    • Abstract
    • 4 agonist, improves abdominal bloating and altered stool consistency in irritable bowel syndrome (IBS). Am J Gastroenterol. 1999;94:A432. Abstract.
    • (1999) Am J Gastroenterol , vol.94
    • Rueegg, P.1    Shi, Y.2    Krumholtz, S.3
  • 83
    • 0036829638 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation
    • Novick J, Miner P, Krause R, et al. A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2002;16:1877-1888.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1877-1888
    • Novick, J.1    Miner, P.2    Krause, R.3
  • 84
    • 0038562985 scopus 로고    scopus 로고
    • Effectiveness and safety of tegaserod in the treatment of irritable bowel syndrome: A meta-analysis of randomized controlled trials
    • Abstract
    • Schoenfeld P, Chey W, Drossman D, et al. Effectiveness and safety of tegaserod in the treatment of irritable bowel syndrome: A meta-analysis of randomized controlled trials. Gastroenterology. 2002;122:A465. Abstract.
    • (2002) Gastroenterology , vol.122
    • Schoenfeld, P.1    Chey, W.2    Drossman, D.3
  • 85
    • 0033033084 scopus 로고    scopus 로고
    • Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart
    • Drici MD, Ebert SN, Wang WX, et al. Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart. J Cardiovasc Pharmacol. 1999;34:82-88.
    • (1999) J Cardiovasc Pharmacol , vol.34 , pp. 82-88
    • Drici, M.D.1    Ebert, S.N.2    Wang, W.X.3
  • 86
    • 0000164178 scopus 로고    scopus 로고
    • 4 receptor partial agonist, is devoid of significant electrocardiographic effects
    • Abstract
    • 4 receptor partial agonist, is devoid of significant electrocardiographic effects. Gastroenterology. 2001;120:A643. Abstract.
    • (2001) Gastroenterology , vol.120
    • Rueegg, P.1    Baldauf, C.2    Appel-Dingemanse, S.3
  • 87
    • 0036732793 scopus 로고    scopus 로고
    • Tegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effects
    • Morganroth J, Rueegg PC, Dunger-Baldauf C, et al. Tegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effects. Am J Gastroenterol. 2002;97:2321-2327.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2321-2327
    • Morganroth, J.1    Rueegg, P.C.2    Dunger-Baldauf, C.3
  • 88
    • 0036792345 scopus 로고    scopus 로고
    • Long-term safety of tegaserod in patients with constipation-predominant irritable bowel syndrome
    • Tougas G, Snape WJ Jr, Otten MH, et al. Long-term safety of tegaserod in patients with constipation-predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2002;16:1701-1708.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1701-1708
    • Tougas, G.1    Snape W.J., Jr.2    Otten, M.H.3
  • 89
    • 0036254583 scopus 로고    scopus 로고
    • Safety and tolerability of tegaserod in patients with irritable bowel syndrome and diarrhea symptoms
    • Fidelhohz J, Smith W, Rawls J, et al. Safety and tolerability of tegaserod in patients with irritable bowel syndrome and diarrhea symptoms. Am J Gastroenterol. 2002;97:1176-1181.
    • (2002) Am J Gastroenterol , vol.97 , pp. 1176-1181
    • Fidelhohz, J.1    Smith, W.2    Rawls, J.3
  • 90
    • 85030808842 scopus 로고    scopus 로고
    • Montvale, NJ: Medical Economics Company
    • Drug Topics Redbook. Montvale, NJ: Medical Economics Company; 2002.
    • (2002) 2002 Drug Topics Redbook
  • 91
    • 18744388283 scopus 로고    scopus 로고
    • Systematic review on the management of irritable bowel syndrome in North America
    • Brandt LJ, Bjorkman D, Fennerty MB, et al. Systematic review on the management of irritable bowel syndrome in North America. Am J Gastroenterol. 2002;97(Suppl 11):S7-S26.
    • (2002) Am J Gastroenterol , vol.97 , Issue.11 SUPPL.
    • Brandt, L.J.1    Bjorkman, D.2    Fennerty, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.