Effect of disopyramide on potassium currents in rabbit ventricular myocytes

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 357, Issue 3, 1998, Pages 268-275

  Virág, Lászlo ^a   Varró, András ^a   Papp, Julius Gy ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Disopyramide; I(K); I(k1); I(to); Patch clamp

Indexed keywords

ANTIARRHYTHMIC AGENT; DISOPYRAMIDE;

ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DRUG EFFECT; HEART REPOLARIZATION; HEART VENTRICLE WALL; MUSCLE CELL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; REPOLARIZATION;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; DISOPYRAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RABBITS;

EID: 0031940530     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005167     Document Type: Article

References (43)

1. Balser JR, Bennett PB, Hondeghem LM, Roden DM (1991) Suppression of time-dependent outward current in guinea-pig ventricular myocytes. Action of quinidine and amiodarone. Circ Res 69 : 519-529
2. + currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ Res 73 : 379-385
3. Buggisch D, Isenberg G, Ravens U, Sclioltysik G (1985) The role of sodium channels in the effects of the cardiotonic DPI 201-106 on contractility and membrane potentials in isolated mammalian heart preparations. Eur J Pharmacol 118 : 303-311
4. + current in cardiac myocytes by dofetilide. J Pharmacol Exp Ther 262 : 809-817
5. + current in rabbit ventricular myocytes. Cardiovasc Drugs Ther 7 [Suppl 3] : 599-604
6. Colatsky TJ. Follmer CH, Starmer CF (1990) Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias. Circulation 82 : 2235-2242
7. Coraboeul E, Carmeliet E (1982) Existance of two transient outward currents in sheep cardiac Purkinje fibers. Pflügers Arch 392 : 352-359
8. Coraboeuf E, Deroubaix E, Escande D, Coulombe A (1988) Comparative effects of three class I antiarrhythmic drugs on plateau and pacemaker currents of sheep cardiac Purkinje fibres. Cardiovasc Res 22 : 375-384
9. + current in guinea pig ventricular myocytes. Voltage-independent and time-dependent block of the slowly activating component. Circ Res 76 : 223-235
10. Escande D, Coulombe A, Faivre JF, Deroubaix E, Coraboeul E (1987) Two types of transient outward currents in adult human atrial cells. Am J Physiol 252 : H142-H148
11. K. by flecainide and E-4031 in cat ventricular myocytes. Circulation 82 : 289-293
12. + current by quinidine in rabbit sinoatrial and atrioventricular nodes. J Pharmacol Exp Ther 251 : 756-763
13. Giles WR, Imaizumi Y (1988) Comparison of potassium currents in rabbit atrial and ventricular cells. J Physiol (Lond) 405: 123-145
14. Gruber R, Carmeliet E (1989) The activation gate of the sodium channel controls blockade and deblockade by disopyramide in rabbit Purkinje fibres. Br J Pharmacol 97 : 41-50
15. Hiraoka M, Kawano S (1989) Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes. J Physiol (Lond) 410 : 187-212
16. Hiraoka M, Sawada K, Kawano S (1986) Effects of quinidine on plateau currents of guinea-pig ventricular myocytes. J Mol Cell Cardiol 18 : 1097-1106
17. Hiraoka M, Kuga K, Kawano S, Sunami A, Fan Z (1989) New observations on the mechanisms of antiarrhythmic actions of disopyramide on cardiac membranes. Am J Cardiol 64:15J-19J
18. Horie M, Hayashi S, Yuzuki Y, Sasayama S (1992) Comparative studies of ATP sensitive potassium channels in heart and pancreatic beta cells using Vaughan-Williams class Ia antiarrhythmics. Cardiovasc Res 26: 1087-1094
19. Imaizumi Y, Giles WR (1987) Quinidine-induced inhibition of transient outward current in cardiac muscle. Am J Physiol 253 : H704-H708
20. Josephson IR, Sanchez-Chapula J, Brown AM (1984) Early outward current in rat single ventricular cells. Circ Res 54: 157-162
21. Kass RS, Arena JP, Walsh B (1990) Measurement and block of potassium channel currents in the heart: importance of channel type. Drug Dev Res 19: 115-127
22. Koch-Weser J (1979) Drug therapy: disopyramide. N Engl J Med 300 : 957-962
23. Kodama I. Toyama J, Yamada K (1986) Open and inactivated sodium channel block by class-I antiarrhythmic drugs. Jpn Heart J 27 [Suppl 1]: 83-89
24. Kotake H, Hasegawa J, Hata T, Mashiba H (1985) Electrophysiological effect of disopyramide on rabbit sinus node cells. J Electrocardiol 18 : 377-383
25. 2+ channels of myocardial cells. Jpn Circ J 52 : 238-242
26. Kus T, Sasyniuk BI (1975) The electrophysiological action of disopyramide phosphate on canine ventricular muscle and Purkinje fibers. Circ Res 37 : 844-854
27. + current by the class Ia agent disopyramide in cat ventricular myocytes. J Pharmacol Exp Ther 272 : 714-723
28. Martin CL, Chinn K (1992) Contribution of delayed rectifier and inward rectifier to repolarization of the action potential: pharmacologic separation. J Cardiovasc Pharmacol 19 : 830-837
29. Martin DK, Nakaya Y, Wyse KR, Campbell TJ (1994) Effects of disopyramide and flecainide on the kinetics of inward rectifier potassium channels in rabbit heart muscle. Br J Pharmacol 111 : 873-879
30. Näbauer M, Beuckelmann DJ, Erdmann E (1993) Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure. Circ Res 73 : 386-394
31. + current: Differential sensitivity to block by Class III antiarrhythmic agents. J Gen Physiol 96 : 195-215
32. Sekiya A, Vaughan-Williams EM (1963) A comparison of the antifibrillatory action and effects on intracellular cardiac potentials of promethalol, disopyramide and quinidine. Br J Pharmacol Chemother 21 : 473-481
33. Shimoni Y, Clark RB, Giles WR (1992) Role of an inwardly rectifying potassium current in rabbit ventricular action potential. J Physiol (Lond) 448 : 709-727
34. + channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. J Pharmacol Exp Ther 269 : 66-74
35. + current by disopyramide and lidocaine in guinea-pig ventricular myocytes. Circ Res 68 : 653-661
36. The CAST investigators (1989) Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia supression after myocardial infarction. N Engl J Med 321 : 406-412
37. Waldo AL, Camm AJ, Ruyter H de, Friedman PL, MacNeil DJ. Pauls JF, Pitt B, Pratt CM, Schwartz PJ, Veltri EP (1996) Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol. Lancet 348(9019) : 7-12
38. Wang Z, Fermini B, Nattel S (1995) Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes. J Pharmacol Exp Ther 272 : 184-196
39. Wettwer E, Amos GJ, Gath J, Zerkowski HR. Reidemeister JC. Ravens U (1993) Transient outward current in human and rat ventricular myocytes. Cardiovasc Res 27 : 1662-1669
40. Wettwer E, Amos GJ, Posival H, Ravens U (1994) Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin. Circ Res 75 : 473-482
41. Wu B, Sato T, Kiyosue T, Arita M (1992) Blockade of 2,4-dinitrophenol-induced ATP sensitive potassium current in guinea-pig ventricular myocytes by class I antiarrhythmic drugs. Cardiovasc Res 26 : 1095-1101
42. Yatani A, Akaike N (1985) Blockade of sodium current in isolated single cells from rat ventricle with mexiletine and disopyramide. J Mol Cell Cardiol 17 : 467-476
43. Zygmunt AC, Gibbons WR (1991) Calcium-activated chloride current in rabbit ventricular myocytes. Circ Res 68 : 424-437