Novel bisubstrate analog inhibitors of serotonin N-acetyltransferase: The importance of being neutral

Bioorganic Chemistry

Volumn 31, Issue 5, 2003, Pages 398-411

  Zheng, Weiping ^a   Cole, Philip A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Catalysis; Inhibitors; pKa; Serotonin N acetyltransferase

Indexed keywords

ACYLTRANSFERASE INHIBITOR; AMINE; CARBENE; SEROTONIN N ACETYLTRANSFERASE;

ARTICLE; CATALYSIS; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SUBSTRATE; HYDROGEN BOND; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

EID: 0041662030     PISSN: 00452068     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-2068(03)00081-6     Document Type: Article

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