A novel gene, Btcl1, encoding CUB and LDLa domains is expressed in restricted areas of mouse brain

Biochemical and Biophysical Research Communications

Volumn 306, Issue 3, 2003, Pages 680-686

  Michishita, Masaki ^a,b   Ikeda, Toshio ^b   Nakashiba, Toshiaki ^b   Ogawa, Masaharu ^b   Tashiro, Kei ^c   Honjo, Tasuku ^c   Doi, Kunio ^a   Itohara, Shigeyoshi ^b   Endo, Shogo ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Axon guidance; Btcl1; CUB; LDLa; Neuropilin; Signal sequence trap

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BRAIN PROTEIN; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S; LOW DENSITY LIPOPROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; NEUROPILIN 1; NEUROPILIN 2; PROTEIN BTCL1; PROTEIN UEGF; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; BTCL1 PROTEIN, MOUSE; NERVE PROTEIN;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; GENE; GENE BTCL1; GENE EXPRESSION; GENE ISOLATION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MOUSE; NEOCORTEX; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OLFACTORY BULB; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; BRAIN; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEUROPILIN-1; NEUROPILIN-2; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; TISSUE DISTRIBUTION;

EID: 0041630623     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01035-0     Document Type: Article

References (24)

1. Tessier-Lavigne M., Goodman C.S. The molecular biology of axon guidance. Science. 274:1996;1123-1133.
2. Obst-Pernberg K., Redies C. Cadherins and synaptic specificity. J. Neurosci. Res. 58:1999;130-138.
3. McCawley L.J., Matrisian L.M. Matrix metalloproteinases: they're not just for matrix anymore! Curr. Opin. Cell Biol. 13:2001;534-540.
4. Dickson B.J. Molecular mechanisms of axon guidance. Science. 298:2002;1959-1964.
5. Sabatini D.D., Kreibich G., Morimoto T., Adesnik M. Mechanisms for the incorporation of proteins in membranes and organelles. J. Cell Biol. 92:1982;1-22.
6. Tashiro K., Tada H., Heilker R., Shirozu M., Nakano T., Honjo T. Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science. 261:1993;600-603.
7. Nakashiba T., Ikeda T., Nishimura S., Tashiro K., Honjo T., Culotti J.G., Itohara S. Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins. J. Neurosci. 20:2000;6540-6550.
8. Liang F., Hatanaka Y., Saito H., Yamamori T., Hashikawa T. Differential expression of γ-aminobutyric acid type receptor-1a and -1b mRNA variants in GABA and non-GABAergic neurons of the rat brain. J. Comp. Neurol. 416:2000;475-495.
9. ′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation Cell. 46:1986;659-667.
10. Bork P., Beckmann G. The CUB domain a widespread module in developmentally regulated proteins. J. Mol. Biol. 231:1993;539-545.
11. Koduri V., Blacklow S.C. Folding determinants of LDL receptor type A modules. Biochemistry. 40:2001;12801-12807.
12. Sugiyama T., Kumagai H., Morikawa Y., Wada Y., Sugiyama A., Yasuda K., Yokoi N., Tamura S., Kojima T., Nosaka T., Senba E., Kimura S., Kadowaki T., Kodama T., Kitamura T. A novel low-density lipoprotein-related protein mediating cellular uptake of apolipoprotein E-enriched β-VLDL in vitro. Biochemistry. 39:2000;15817-15825.
13. Ishii H., Kim D.-H., Fujita T., Endo Y., Saeki S., Yamamoto T.T. cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13.2. Genomics. 51:1998;132-135.
14. Qing J., Wei D., Maher V.M., McCormick J.J. Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines. Oncogene. 18:1999;335-342.
15. Lecain E., Zelenika D., Laine M.-C., Rhyner T., Pessac B. Isolation of a novel cDNA corresponding to a transcript expressed in the choroid plexus and leptomeninges. J. Neurochem. 56:1991;2133-2138.
16. Takahara K., Brevard R., Hoffman G.G., Suzuki N., Greenspan D.S. Characterization of a novel geneproduct (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1. Genomics. 34:1996;157-165.
17. Herz J. The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron. 29:2001;571-581.
18. Takahashi S., Kawarabayasi Y., Nakai T., Sakai J., Yamamoto T. Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc. Natl. Acad. Sci. USA. 89:1992;9252-9256.
19. Kolodkin A.L., Levengood D.V., Rowe E.G., Tai Y.-U., Giger R.J., Ginty D.D. Neuropilin is a semaphorin III receptor. Cell. 90:1997;753-762.
20. He Z., Tessier-Lavigne M. Neuropilin is a receptor for the axonal chemorepellent semaphorin III. Cell. 90:1997;739-751.
21. Giger R.J., Urquhart E.R., Gillespie S.K.H., Levengood D.V., Ginty D.D., Kolodkin A.L. Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity. Neuron. 21:1998;1079-1092.
22. Nakamura F., Tanaka M., Takahashi T., Kalb R.G., Strittmatter S.M. Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron. 21:1998;1093-1100.
23. Giger R.J., Jeroen Pasterkamp R., Heijnen S., Holtmaat A.J.G.D., Verhaagen J. Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: predominant expression in structures of the olfactory-hippocampal pathway and the motor system. J. Neurosci. Res. 52:1998;27-42.
24. Stöhr H., Berger C., Fröhlich S., Weber B.H.F. A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain. Gene. 286:2002;223-231.