From Eden to a hell of uniformity? Directed evolution in humans

BioEssays

Volumn 25, Issue 8, 2003, Pages 815-821

  Brosius, Jürgen ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME ANALYSIS; DIRECTED MOLECULAR EVOLUTION; DISEASE ASSOCIATION; GENE FREQUENCY; GENE TECHNOLOGY; GENE THERAPY; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC ENHANCEMENT; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; GENETIC VARIABILITY; GENOMICS; GENOTYPE ENVIRONMENT INTERACTION; GENOTYPE PHENOTYPE CORRELATION; GERM LINE; HOMOZYGOSITY; HUMAN; MOLECULAR CLONING; NONHUMAN; POPULATION GENETICS; PREDICTION; PRENATAL DIAGNOSIS; REPRODUCTION; REVIEW; SPECIES DIFFERENCE;

BIOMEDICAL AND BEHAVIORAL RESEARCH; GENETICS AND REPRODUCTION;

ALLELES; DIRECTED MOLECULAR EVOLUTION; FEMALE; GENETIC ENHANCEMENT; GENOTYPE; HUMANS; MALE; PHENOTYPE; REPRODUCTION; VARIATION (GENETICS);

EID: 0041589712     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.10313     Document Type: Review

References (71)

1. Brosius J. Gene duplication and other evolutionary strategies: from the RNA world to the future. J Struct Funct Genomics 2003;3:1-17.
2. Silver LM. Remaking Eden. Cloning and beyond in a brave new world. New York: Avon. 1997.
3. Brosius J, Kreitman M. Eugenics - evolutionary nonsense? Nat Genet 2000;25:253.
4. Mayr E. Animal species and evolution. Cambridge, MA: The Belknap Press of Harvard University Press. 1963.
5. Smith JM. Eugenics and Utopia. Daedalus 1965;94:487-505.
6. Robertson KD, Wolffe AP. DNA methylation in health and disease. Nat Rev Genet 2000;1:11-19.
7. Nicholls RD, Knepper JL. Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes. Annu Rev Genomics Hum Genet 2001;2:153-175.
8. Reik W, Walter J. Genomic imprinting: parental influence on the genome. Nat Rev Genet 2001;2:21-32.
9. Weinstein LS. The role of tissue-specific imprinting as a source of phenotypic heterogeneity in human disease. Biol Psychiatry 2001;50:927-931.
10. Scriver CR, Waters PJ. Monogenic traits are not simple: lessons from phenylketonuria. Trends Genet 1999;15:267-272.
11. Gerlai R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 1996;19:177-181.
12. Lathe R. Mice, gene targeting and behaviour: more than just genetic background. Trends Neurosci 1996;19:183-186.
13. Routtenberg A. Knockout mouse fault lines. Nature 1995;374:314-315.
14. Routtenberg A. Reverse piedpiperase: is the knockout mouse leading neuroscientists to a watery end? Trends Neurosci 1996;19:471-472.
15. Wolfer DP, Crusio WE, Lipp HP. Knockout mice: simple solutions to the problems of genetic background and flanking genes. Trends Neurosci 2002;25:336-340.
16. Zimmer A. Gene targeting and behaviour: a genetic problem requires a genetic solution. Trends Neurosci 1996;19:470.
17. deBelle JS, Heisenberg M. Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: A case study of the mushroom body miniature gene (mbm). Proc Natl Sci USA 1996;93:9875-9880.
18. Gottesman II, Shields J. Schizophrenia: geneticism and environmentalism. Hum Hered 1971;21:517-522.
19. Gottesman II, Bertelsen A. Confirming unexpressed genotypes for schizophrenia. Risks in the offspring of Fischer's Danish identical and fraternal discordant twins. Arch Gen Psychiatry 1989;46:867-872.
20. Reiss D, Plomin R, Hetherington EM. Genetics and psychiatry: an unheralded window on the environment. Am J Psychiatry 1991;148:283-291.
21. Nesse RM, Williams GC. Why we get sick. The new science of Darwinian medicine. 1995.
22. Hacia JG. Genome of the apes. Trends Genet 2001;17:637-645.
23. Ebersberger I, Metzler D, Schwarz C, Paabo S. Genomewide comparison of DNA sequences between humans and chimpanzees. Am J Hum Genet 2002;70:1490-1497.
24. Olson MV, Varki A. Sequencing the chimpanzee genome: insights into human evolution and disease. Nat Rev Genet 2003;4:20-28.
25. Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, Kitano T, Monaco AP, Pääbo S. Molecular evolution of FOXP2, a gene involved in speech and language. Nature 2002;418:869-872.
26. Haldane JBS. Possible Worlds, and Other Essays. London: Chatto and Windus. 1927.
27. Leakey R, Lewin R. The sixth extinction. Patterns of life and the future of humankind. New York: Doubleday. 1995.
28. Heinberg R. Cloning the Buddha. The Moral Impact of Biotechnology. Wheaton, IL: Quest. 1999.
29. Hamilton WD. Narrow Roads of Gene Land. Evolution of Sex. Oxford, New York: Oxford University Press. 2001.
30. Ridley M. The Red Queen. Sex and the Evolution of Human Nature. New York: MacMillan. 1994.
31. Apanius V, Penn D, Slev PR, Ruff LR, Potts WK. The nature of selection on the major histocompatibility complex. Crit Rev Immunol 1997;17:179-224.
32. Feder JN, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996;13:399-408.
33. Samson M, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-725.
34. Dean M, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996;273:1856-1862.
35. Huang Y, et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996;2:1240-1243.
36. Bardo MT, Donohew RL, Harrington NG. Psychobiology of novelty seeking and drug seeking behavior. Behav Brain Res 1996;77:23-43.
37. Galen LW, Henderson MJ, Whitman RD. The utility of novelty seeking, harm avoidance, and expectancy in the prediction of drinking. Addict Behav 1997;22:93-106.
38. Ebstein RP, Benjamin J, Belmaker RH. Genetics of personality dimensions. Curr Opin Psychiatry 2000;13:617-622.
39. Charman T. Autism and the pervasive developmental disorders. Curr Opin Neurol 1999;12:155-159.
40. Bailey A, Palferman S, Heavey L, Le Couteur A. Autism: the phenotype in relatives. J Autism Dev Disord 1998;28:369-392.
41. Cook EH Jr. Genetics of autism. Child Adolesc Psychiatr Clin N Am 2001;10:333-350.
42. Pickles A, Starr E, Kazak S, Bolton P, Papanikolaou K, Bailey A, Goodman R, Rutter M. Variable expression of the autism broader phenotype: findings from extended pedigrees. J Child Psychol Psychiatry 2000;41:491-502.
43. Piven J. The broad autism phenotype: a complementary strategy for molecular genetic studies of autism. Am J Med Genet 2001;105:34-35.
44. Grandin T. Thinking in Pictures. And Other Reports from My Life with Autism. New York: Vintage Books. 1995.
45. Baron-Cohen S, Wheelwright S, Stott C, Bolton P, Goodyer I. Is there a link between engineering and autism? Autism 1997;1:101-109.
46. Baron-Cohen S, Wheelwright S, Skinner R, Martin J, Clubley E. The autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. J Autism Dev Disord 2001;31:5-17.
47. Baron-Cohen S, Bolton P, Wheelwright S, Short L, Mead G, Smith A, Scahill V. Autism occurs more often in families of physicists, engineers, and mathematicians. Autism 1998;2:296-301.
48. Baron-Cohen S, Hammer J. Parents of children with Asperger syndrome: What is the cognitive phenotype? J Cogn Neurosci 1997;9:548-554.
49. Baron-Cohen S, Hammer J. Is autism an extreme form of the male brain? Adv Inf Res 1997;11:193-217.
50. Happé F, Briskman J, Frith U. Exploring the cognitive phenotype of autism: weak "central coherence" in parents and siblings of children with autism: I. Experimental tests. J Child Psychol Psychiatry 2001;42:299-307.
51. Carlson EA. The Unfit: History of a Bad Idea. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. 2001.
52. Little P. Genetic Destinies. Oxford, New York: Oxford University Press. 2002.
53. Weizenbaum J. Computer power and human reason. From judgement to calculation. San Francisco: W.H. Freeman and Company. 1976.
54. Goldstein JL. Laskers for 2001: knockout mice and test-tube babies. Nat Med 2001;7:1079-1080.
55. Stock G. Redesigning humans. Our inevitable genetic future. Boston, New York: Houghton Mifflin. 2002.
56. Smith JM. On Evolution. Edinburgh: Edinburgh University Press. 1972.
57. Gould SJ. The mismeasure of man. The definite refutation to the argument of The Bell Curve. 1981.
58. Lewontin RC, Rose S, Kamin LJ. Not in Our Genes. Biology, Ideology, and Human Nature. New York: Pantheon. 1984.
59. Schiff M, Lewontin R. Education and class. The irrelevance of IQ genetic studies. 1986.
60. Rose S. What is wrong with reductionist explanations of behaviour? In: Bock GR, Goode JA, editors. The limits of reductionism in biology. Chichester: John Wiley & Sons. 1998. p 176-192.
61. Lewontin R. It ain't necessarily so. The dream of the human genome and other illusions. 2000.
62. Stogdill R. Handbook of leadership. New York: Free Press. 1974.
63. Frieze IH, Olson JE, Good DC. Perceived and actual discrimination in the salaries of male and female managers. J Appl Soc Psychol 1990;20:46-67.
64. Teasdale TW, Owen DR, Sorensen TI. Intelligence and educational level in adult males at the extremes of stature. Hum Biol 1991;63:19-30.
65. Jackson LA. Physical appearance and gender: sociobiology and sociocultural perspectives. Albany: State University of New York Press. 1992.
66. Buss DM. The evolution of desire: strategie of human mating. New York: Basic Books. 1994.
67. Hensley WE, Cooper R. Height and occupational success: a review and critique. Psychol Rep 1987;60:843-849.
68. Pawlowski B, Dunbar RI, Lipowicz A. Tall men have more reproductive success. Nature 2000;403:156.
69. Mueller U, Mazur A. Evidence of unconstrained directional selection for male tallness. Behav Ecol Sociobiol 2001;50:302-311.
70. Hayes B. Experimental Lamarckism. Am Sci 1999;87:494-498.
71. Kling J. The flaw is human. Nature 2000;406:941.