Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies

Human Genetics

Volumn 113, Issue 3, 2003, Pages 253-257

  Huang, Qiqing ^a   Fu, Yun Xin ^a   Boerwinkle, Eric ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CASE CONTROL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; PRIORITY JOURNAL; SAMPLE SIZE; SAMPLING; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

CASE-CONTROL STUDIES; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; PATIENT SELECTION; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS; SAMPLE SIZE;

EID: 0041563906     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-003-0965-x     Document Type: Article

References (19)

1. Ardlie KG, Kruglyak L, Seielstad M (2002) Patterns of linkage disequilibrium in the human genome. Nat Rev Genet 3:299-309
2. Churchill GA, Doerge RW (1994) Empirical threshold values for quantitative trait mapping. Genetics 138:963-971
3. Clark AG, Weiss KM, Nickerson DA, Taylor SL, Buchanan A, Stengard J, Salomaa V, Vartiainen E, Perola M, Boerwinkle E, Sing CF (1998) Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet 63:595-612
4. Collins FS, Guyer MS, Charkravati A (1997) Variations on a theme: Cataloging human DNA sequence variation. Science 278:1580-1581
5. Daly M, Rioux J, Schaffner S, Hudson T, Lander E (2001) High-resolution haplotype structure in the human genome. Nat Genet 29:229-232
6. Das M, Burge CB, Park E, Colinas J, Pelletier J (2001) Assessment of the total number of human transcription units. Genomics 77:71-78
7. Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, Schork N (2001) Genetic analysis of case/control data using estimated haplotype frequencies: Application to APOE locus variation and Alzheimer's disease. Genome Res 11:143-151
8. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, AltshulerD (2002) The structure of haplotype blocks in the human genome. Science 296:2225-2229
9. Hudson RR (1983) Properties of a neutral allele model with intergenic recombination. Theor Popul Biol 23:183-201
10. Jeffreys A, Kauppi L, Neumann R (2001) Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat Genet 29:217-222
11. Johnson G, Esposito L, Barratt BJ, Smith A, Heward J, Genova G, Ueda H, Cordell H, Eaves I, Dudbridge F, Twells R, Payne F, Hughes W, Nutland S, Stevens H, Carr P, Tuomilehto-Wolf E, Tuomilehto J, Gough S, Clayton D, Todd J (2001) Haplotype tagging for the identification of common disease genes. Nat Genet 29:233-237
12. Kruglyak L (1999) Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet 22:139-144
13. Long AD, Langley CH (1999) The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res 9:720-731
14. Petes TD (2001) Meiotic recombination hot spots and cold spots. Nat Rev Genet 2:360-369
15. Reich D, Cargill M, Bolk S, Ireland J, Sabeti P, Richter D, Lavery T, Kouyoumijian R, Farhadian S, Ward R, Lander E (2001) Linkage disequilibrium in the human genome. Nature 411:199-204
16. Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1516-1517
17. Suchard MA, Bailey JN, Elashoff DA, Sinsheimer JS (2001) SNPing away at candidate genes. Genet Epidemiol 21 (Suppl 1): S643-S648
18. Zhao JH, Curtis D, Sham PC (2000) Model-free analysis and permutation tests for allelic associations. Hum Hered 50:133-139
19. Zollner S, Von Haeseler A (2000) A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms. Am J Hum Genet 66:615-628