Multiple signalling pathways connect chemoattractant receptors and calcium channels in Dictyostelium

Journal of Muscle Research and Cell Motility

Volumn 23, Issue 7-8, 2002, Pages 853-865

  Nebl, Thomas ^a,c   Kotsifas, Martha ^a   Schaap, Pauline ^b,d   Fisher, Paul R ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b LEIDEN UNIVERSITY   (Netherlands)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM 45; CALCIUM CHANNEL; CALCIUM ION; CHEMOATTRACTANT; CYCLIC AMP; CYCLIC AMP RECEPTOR; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP PHOSPHODIESTERASE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; RNA;

ARTICLE; CALCIUM CELL LEVEL; CHEMOTAXIS; DICTYOSTELIUM DISCOIDEUM; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; TEMPERATURE SENSITIVITY;

ANIMALS; CALCIUM CHANNELS; CHEMORECEPTORS; CYCLIC AMP; DICTYOSTELIUM; FOLIC ACID; KINETICS; RNA, PROTOZOAN; SECOND MESSENGER SYSTEMS;

DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; PROTOZOA;

EID: 0041517716     PISSN: 01424319     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024496232604     Document Type: Article

References (70)

1. 2+ concentration in suspensions of differentiating D. discoideum cells. J Cell Biol 98: 173-178.
2. Bumann J, Malchow D and Wurster B (1986) Oscillations of calcium concentration during the cell differentiation of Dictyostelium discoideum. Differentiation 31: 85-91.
3. Chung CY and Firtel RA (1999) PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J Cell Biol 147: 559-576.
4. Chung CY, Funamoto S and Firtel RA (2001) Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci 26: 557-566.
5. Coukell MB and Cameron AM (1986) Characterization of revertants of stmF mutants of Dictyostelium discoideum: evidence that stmF is the structural gene of the cGMP-specific phosphodiesterase. Dev Genet 6: 163-177.
6. Cubitt AB, Firtel RA, Fischer G, Jaffe LF and Miller AL (1995) Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin. Development 121: 2291-2301.
7. De Wit RJW, Bulgakov R, Pinas R and Konijn TM (1985) Relationships between the ligand specificity of cell surface folate binding sites, folate degrading enzymes and cellular responses in Dictyostelium discoideum Biochim Biophys Acta 814: 214-226.
8. De Wit RJW and Snaar Jagalska BE (1985) Folate and cAMP modulate GTP binding to isolated membranes of Dictyostelium discoideum. Functional coupling between cell surface receptors and G-proteins. Biochim Biophys Acta 129: 11-17.
9. Drayer AL, Van der Kaay J, Mayr GW and Van Haastert PJ (1994) Role of phospholipase C in Dictyostelium: formation of inositol 1,4,5-trisphosphate and normal development in cells lacking phospholipase C activity. EMBO J 13: 1601-1609.
10. Europe-Finner GN and Newell PC (1986) Inositol 1,4,5-trisphosphate and calcium stimulate actin polymerization in Dictyostelium discoideum. J Cell Sci 82: 41-51.
11. Europe-Finner GN and Newell PC (1987) Cyclic AMP stimulates accumulation of inositol trisphosphate in Dictyostelium. J Cell Sci 87 (Pt2): 221-229.
12. Ferris CD, Cameron AM, Bredt DS, Huganir RL and Snyder SH (1991a) Inositol 1,4,5-trisphosphate receptor is phosphorylated by cyclic AMP-dependent protein kinase at serines 1755 and 1589. Biochem Biophys Res Commun 175: 192-198.
13. Ferris CD, Huganir RL, Bredt DS, Cameron AM and Snyder SH (1991b) Inositol trisphosphate receptor: phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles. Proc Natl Acad Sci USA 88: 2232-2235.
14. Firtel R and Chung CY (2000) The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients. BioEssays 22: 603-615.
15. Flaadt H, Jaworski E and Malchow D (1993a) Evidence for two intracellular calcium pools in Dictyostelium: the cAMP-induced calcium influx is directed into a NBD-Cl- and 2,5-di-(tert-butyl) 1,4-hydroquinone-sensitive pool. J Cell Sci 105 (Pt 4): 1131-1135.
16. 2+ entry across the plasma membrane. J Cell Sci 105: 255-261.
17. Gaskins C, Clark AM, Aubry L, Segall JE and Firtel RA (1996) The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev 10: 118-128.
18. Hadwiger JA, Lee S and Firtel RA (1994) The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium. Proc Natl Acad Sci USA 91: 10,566-10,570.
19. 2+ and trp. Cell Calcium 18: 256-274.
20. Insall RH, Borleis J and Devreotes PN (1996) The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium. Curr Biol 6: 719-729.
21. Jaffe LF (1997) The roles of calcium in pattern formation. In: Maeda Y, Inouye K and Takeuchi I (ed.) Dictyostelium - A Model System for Cell and Developmental Biology (pp. 267-277) Universal Academic Press, Tokyo.
22. Jin T, Soede RD, Liu J, Kimmel AR, Devreotes PN and Schaap P (1998) Temperature-sensitive Gbeta mutants discriminate between G protein-dependent and -independent signaling mediated by serpentine receptors. EMBO J 17: 5076-5084.
23. Jin T, Zhang N, Long Y, Parent CA and Devreotes PN (2000) Localization of the G protein betagamma complex in living cells during chemotaxis. Science 287: 1034-1036.
24. Kim J, Van Haastert P and Devreotes PN (1996) Social senses: G-protein-coupled receptor signaling pathways in Dictyostelium discoideum. Current Biology 3: 239-243.
25. Knetsch ML, Epskamp SJ, Schenk PW, Wang Y, Segall JE and Snaar-Jagalska BE (1996) Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum. EMBO J 15: 3361-3368.
26. Komalavilas P and Lincoln TM (1994) Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase. J Biol Chem 269: 8701-8707.
27. Kuspa A (1995) Analysis of gene function in Dictyostelium. Experientia 51: 1116-1123.
28. Kuwayama H, Ishida S and Van Haastert PJ (1993) Non-chemotactic Dictyostelium discoideum mutants with altered cGMP signal transduction. J Cell Biol 123: 1453-1462.
29. 2+ influx in Dictyostelium discoideum. Biochim Biophys Acta 1402: 102-108.
30. Kuwayama H, Viel GT, Ishida S and Van Haastert PJ (1995) Aberrant cGMP-binding activity in non-chemotactic Dictyostelium discoideum mutants. Biochim Biophys Acta 1268: 214-220.
31. Lee CH, Parent CA, Insall R and Firtel RA (1999) A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol Biol Cell 10: 2829-2845.
32. Lilly P, Wu L, Welker DL and Devreotes PN (1993) A G-protein beta-subunit is essential for Dictyostelium development. Genes Dev 7: 986-995.
33. Ma H, Gamper M, Parent C and Firtel RA (1997) The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase. EMBO J 16: 4317-4332.
34. Maeda M, Aubry L, Insall R, Gaskins C, Devreotes PN and Firtel RA (1996) Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of hetero-trimeric G proteins. J Biol Chem 271: 3351-3354.
35. Maeda Y, Inouye K and Takeuchi I (1997) Dictyostelium - A Model System for Cell and Developmental Biology. Universal Academic Press, Tokyo.
36. Malchow D, Mutzel R and Schlatterer C (1996) On the role of calcium during chemotactic signalling and differentiation of the cellular slime mould Dictyostelium discoideum. Int J Dev Biol 40: 135-139.
37. Maniak M, Saur U and Nellen W (1989) A colony-blot technique for the detection of specific transcripts in eukaryotes. Anal Biochem 176: 78-81.
38. Meili R, Ellsworth C, Lee S, Reddy TB, Ma H and Firtel RA (1999) Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J 18: 2092-2105.
39. 2+ uptake in Dictyostelium. J Cell Sci 99 (Pt 1): 187-191.
40. 2+ transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors. J Cell Biol 112: 103-110.
41. 2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism. Mol Biol Cell 4: 283-292.
42. 2+ entry in the absence of functional G proteins in Dictyostelium. J Biol Chem 270: 5926-5931.
43. Mutzel R (1995) Molecular biology, growth and development of the cellular slime mold Dictyostelium discoideum. Experientia 51: 1103-1196.
44. 2+ influx. J Cell Sci 110 (Pt22): 2845-2853.
45. Newell PC, Malchow D and Gross JD (1995) The role of calcium in aggregation and development of Dictyostelium. Experientia 51: 1155-1165.
46. Pan P, Hall EM and Bonner JT (1972) Folic acid as a second chemotactic substance in the cellular slime moulds. Nature 237: 181-182.
47. Parent CA and Devreotes PN (1999) A cell's sense of direction. Science 284: 765-770.
48. Peracino B, Borleis J, Jin T, Westphal M, Schwartz JM, Wu L, Bracco E, Gerisch G, Devreotes P and Bozzaro S (1998) G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton. J Cell Biol 141: 1529-1537.
49. 2+ influx into Drosophila photoreceptors. J Gen Physiol 104: 1057-1077.
50. Pinter K and Gross J (1995) Calcium and cell-type-specific gene expression in Dictyostelium. Differentiation 59: 201-206.
51. Ranganathan R, Bacskai BJ, Tsien RY and Zuker CS (1994) Cytosolic calcium transients: spatial localization and role in Drosophila photoreceptor cell function. Neuron 13: 837-848.
52. Rogers KC, Ginsburg GT, Mu XG, R, Balint-Kurti P, Louis J and Kimmel AR (1997) The cAMP receptor gene family of Dictyostelium discoideum: expression, regulation, function. In: Maeda Y, Inouye K and Takeuchi I (eds) Dictyostelium - A Model System for Cell and Developmental Biology (pp. 163-292) Universal Academy Press, Tokyo.
53. Ross FM and Newell PC (1981) Streamers: chemotactic mutants of Dictyostelium discoideum with altered cyclic GMP metabolism. J Gen Microbiol 127 (Pt2): 339-350.
54. 2+ influx in Dictyostelium: role of phospholipase A2. Biochem J 327 (Pt1): 233-238.
55. 2+ entry in Dictyostelium discoideum. Biochem J 332 (Pt2): 541-548.
56. Schenk PW, Nebl T, Fisher PR and Snaar-Jagalska BE (1999) A serpentine receptor-dependent, Gbeta- and Ca(2+) influx-independent pathway regulates mitogen-activated protein kinase ERK2 in Dictyostelium. Biochem Biophys Res Commun 260: 504-509.
57. 2+. Biochem J 313 (Pt2): 661-667.
58. Segall JE, Kuspa A, Shaulsky G, Ecke M, Maeda M, Gaskins C, Firtel RA and Loomis WF (1995) A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J Cell Biol 128: 405-413.
59. Sonnemann J, Aichem A and Schlatterer C (1998) Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum: the role of cAMP receptor subtypes and G protein subunits. FEBS Lett 436: 271-276.
60. Traynor D, Milne JL, Insall RH and Kay RR (2000) Ca(2+) signalling is not required for chemotaxis in Dictyostelium. EMBO J 19: 4846-4854.
61. Valkema R and Van Haastert PJ (1994) A model for cAMP-mediated cGMP response in Dictyostelium discoideum. Mol Biol Cell 5: 575-585.
62. 2+ influx. Eur J Biochem 244: 113-119.
63. Van Dijken P, de Haas JR, Craxton A, Erneux C, Shears SB and Van Haastert PJ (1995) A novel, phospholipase C-independent pathway of inositol 1,4,5-trisphosphate formation in Dictyostelium and rat liver. J Biol Chem 270: 29,724-29,731.
64. Van Haastert PJ, De Vries MJ, Penning LC, Roovers E, Van der Kaay J, Erneux C and Van Lookeren Campagne MM (1989) Chemoattractant and guanosine 5′-[gamma-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in Dictyostelium cells that are labelled with [3H]inositol by electroporation. Biochem J 258: 577-586.
65. Van Haastert PJM, Van Lookeren-Campagne MM and Kesbeke F (1983) Multiple degradation pathways of chemoattractant mediated cyclic GMP accumulation in Dictyostelium. Biochim Biophys Acta 756: 67-71.
66. Verkerke-Van Wijk I and Schaap P (1997) cAMP, a signal for survival. In: Maeda Y, Inouye K and Takeuchi I (ed) Dictyostelium - A Model System for Cell and Developmental Biology (pp. 145-162) Universal Academic Press, Tokyo.
67. Wang Y, Liu J and Segall JE (1998) MAP kinase function in amoeboid chemotaxis. J Cell Sci 111 (Pt3): 373-383.
68. Wetterauer B, Morandini P, Hribar I, Murgia-Morandini I, Hamker U, Singleton C and Macwilliams HK (1996) Wild-type strains of Dictyostelium discoideum can be transformed using a novel selection cassette driven by the promoter of the ribosomal V18 gene. Plasmid 36: 169-181.
69. Wu L, Valkema R, Van Haastert P and Devreotes PN (1995) The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium. J Cell Biol 129: 1667-1675.
70. Yumura S, Furuya K and Takeuchi I (1996) Intracellular free calcium responses during chemotaxis of Dictyostelium cells. J Cell Sci 109 (Pt 11): 2673-2678.