Endothelial and platelet activation in acute ischemic stroke and its etiological subtypes

Stroke

Volumn 34, Issue 9, 2003, Pages 2132-2137

  Cherian, Paul ^a,b   Hankey, Graeme J ^a,b   Eikelboom, John W ^a,b   Thom, Jim ^b   Baker, Ross I ^a,b   McQuillan, Andrew ^b   Staton, Janelle ^b   Yi, Qilong ^c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Activation; Endothelium; Platelets; Selectins; Stroke, acute; Stroke, ischemic

Indexed keywords

CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTERY; ARTICLE; ATHEROGENESIS; CASE CONTROL STUDY; CELL ACTIVATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE CLASSIFICATION; EMBOLISM; ENDOTHELIUM CELL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMBRANE VESICLE; PLATELET DERIVED MICROVESICLE; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; STROKE; THROMBOCYTE ACTIVATION; THROMBOSIS; VASCULAR ENDOTHELIUM;

ACUTE DISEASE; AGED; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; CEREBROVASCULAR ACCIDENT; COMORBIDITY; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; ODDS RATIO; P-SELECTIN; PLATELET ACTIVATION; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; SUBCELLULAR FRACTIONS; VON WILLEBRAND FACTOR; WESTERN AUSTRALIA;

EID: 0041416281     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000086466.32421.F4     Document Type: Article

References (32)

1. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115-126.
2. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314,
3. Tedder TF, Steeber DA, Chen A, Engel P. The selectins: vascular adhesion molecules. FASEB J. 1995;9:866-873.
4. Davies MJ, Gordon JL, Gearing AJ, et al. The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis. J Pathol. 1993;171:223-229.
5. Dong ZM, Chapman SM, Brown AA, et al. The combined role of P- and E-selectins in atherosclerosis. J Clin Invest. 1998;102:145-152.
6. Collins RG, Velji R, Guevara NV, et al. P-selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med. 2000;191:189-194.
7. Frijns CJM, Kappelle LJ. Inflammatory cell adhesion molecules in ischemic cerebrovascular disease. Stroke. 2002;33:2115-2122.
8. Enlimomab Acute Stroke Trial Investigators. Use of anti-ICAM therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial. Neurology. 2001;57:1428-1434.
9. Hwang SJ, Ballantyne CM, Sharrett AR, et al. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation. 1997;96:4219-4225.
10. Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J. Plasma concentrations of soluble intercellular adhesion moleeule 1 and risks of future myocardial infarction in apparently healthy men. Lancet. 1998;351:88-92.
11. Ridker PM, Buring JE, Rifai N. Soluble P-selectin and risk of future cardiovascular events. Circulation. 2001;103:491-495.
12. Blankenberg S, Rupprecht HJ, Bickel C, Peetz D, Hafner G, Tiret L, Meyer J, for the AtheroGene Investigators. Circulating cell adhesions molecules and death in patients with coronary artery disease. Circulation. 2001;104:1336-1342.
13. Malik I, Danesh J, Whincup P, Bhatia V, Papacosta O, Walker M, Lennon L, Thomson A, Haskard D. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet. 2001;358:971-975.
14. Ridker PM. Role of inflammatory biomarkers in prediction of coronary heart disease. Lancet. 2001;358:946-948.
15. Huang J, Choudhri TF, Winfree CJ, et al. Post-ischemic cerebrovascular E-selectin expression mediates tissue injury in murine stroke. Stroke. 2000;31:3047-3053.
16. del Zoppo GJ, Schmid-Schonbein GW, Mori E, et al. Polymorphonuclear leucocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke. 1991;22:1276-1283.
17. Prestigiacomo CJ, Kim SC, Connolly ES Jr, Liao H, Yan SF, Pinsky DJ. CD-18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke. Stroke. 1999;30:1110-1117.
18. Blann AD, Ridker PM, Lip GYH. Inflammation, cell adhesion molecules, and stroke: tools in pathophysiology and epidemiology? Stroke. 2002;33:2141-2143.
19. Hatano S. Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ. 1976;54:541-553.
20. Warlow CP, Dennis MS, van Gijn J, Hankey GJ, Sandercock PAG, Bamford JM. Stroke: A Practical Guide to Management. Oxford, UK: Blackwell Scientific Productions; 1996.
21. Eikelboom JW, Hankey GJ, Anand SS, Lofthouse E, Staples N, Baker RI. Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiological subtypes of ischemic stroke. Stroke. 2000;31:1069-1075.
22. Frijns CJM, Kappelle LJ, van Gijn J, Niewenhuis HK, Sixma JJ, Fijnheer R. Soluble adhesion molecules in ischemic stroke and in carotid atherosclerosis. Stroke. 1997;28:2214-2218.
23. Fassbender K, Bertsch T, Mielke O, Mühlhauser F, Hennerici M. Adhesion molecules in cerebrovascular disease: evidence for an inflammatory endothelial activation and large- and small-vessel disease. Stroke. 1999;30:1647-1650.
24. Blann A, Kumar P, Krupinski J, McCollom C, Beevers DG, Lip GY. Soluble intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1 and von Willebrand factor in stroke. Blood Coag Fibrinol. 1999;10:277-284.
25. Catto AJ, Carter AM, Barrett JH, Bamford J, Rice PJ, Grant PJ. Von Willebrand factor and factor VIII:C in acute cerebrovascular disease: relationship to stroke subtype and mortality. Thromb Haemost. 1997;77:1104-1108.
26. Bath P, Blann A, Smith N, Butterworth RJ. Von Willebrand factor, P-selectin, and fibrinogen levels in patients with acute ischemic and haemorrhagic stroke, and their relationship with stroke sub-type and functional outcome. Platelets. 1998;9:155-159.
27. Fassbender K, Mossner R, Motsch L, Kischka U, Grau A, Hennerici M. Circulating selectin- and immunoglobulin-type adhesion molecules in acute ischemic stroke. Stroke. 1995;26:1361-1364.
28. Shyu K-G, Chang H, Lin C-C. Serum levels of intercellular adhesion molecule-1 and E-selectin in patients with acute ischemic stroke. J Neurol. 1997;244:90-93.
29. Hankey GJ, Jamrozik K, Broadhurst RJ, Forbes S, Burvill PW, Anderson CS, Stewart-Wynne EG. Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study. Stroke. 2000;31:2080-2086.
30. Hankey GJ, Jamrozik K, Broadhurst RJ, Forbes S, Burvill PW, Anderson CS, Stewart-Wynne EG. Long-term risk of first recurrent stroke in the Perth Community Stroke Study. Stroke. 1998;29:2491-2500.
31. Fenton JW, Shen GX. Statins as cellular antithrombotics. Haemostasis. 1999;29:166-169.
32. Pernerstoffer T, Eichler H-G, Stohlawetz P, Speiser W, Jilma B. Effects of heparin and aspirin on circulating P-selectin, E-selectin and von Willebrand factor levels in healthy men. Atherosclerosis. 2001;155:389-393.