Modulation of circulating endothelin-1 and big endothelin by nitric oxide inhalation following left ventricular assist device implantation

Circulation

Volumn 108, Issue 10 SUPPL., 2003, Pages

  Wagner, Frank D ^a   Buz, Semih ^b   Knosalla, Christoph ^b   Hetzer, Roland ^b   Hocher, Berthold ^b  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b NONE

Author keywords

Endothelin; Heart assist device; Nitric oxide

Indexed keywords

ENDOTHELIN; ENDOTHELIN 1; NITRIC OXIDE;

ADULT; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DOSE TIME EFFECT RELATION; FEMALE; HEART ASSIST DEVICE; HEART RIGHT VENTRICLE; HUMAN; LUNG BLOOD VESSEL; MALE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PULMONARY HYPERTENSION; STATISTICAL SIGNIFICANCE; VASODILATATION; WEANING;

ADMINISTRATION, INHALATION; ADULT; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENDOTHELINS; FEMALE; HEART-ASSIST DEVICES; HEMODYNAMIC PROCESSES; HUMANS; HYPERTENSION, PULMONARY; KINETICS; MALE; MIDDLE AGED; NITRIC OXIDE; PROTEIN PRECURSORS;

EID: 0041414497     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Moraes DL, Colucci WS, Givertz MM. Secondary pulmonary hypertension in chronic heart failure: the role of the endothelium in pathophysiology and management. Circulation. 2000;102:1718-23.
2. Stewart DJ, Levy RD, Cernacek P, Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med. 1991;114:464-9.
3. Wei CM, Lerman A, Rodeheffer RJ, et al. Endothelin in human congestive heart failure. Circulation. 1994;89:1580-6.
4. Stangl K, Dschietzig T, Richter C, et al. Pulmonary release and coronary and peripheral consumption of big endothelin and endothelin-1 in severe heart failure: acute effects of vasodilator therapy. Circulation. 2000;102:1132-8.
5. Tsutamoto T, Wada A, Maeda Y, et al. Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure. J Am Coll Cardiol. 1994;23:1427-33.
6. Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 1993;328:1732-9.
7. Channick RN, Simonneau G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001;358:1119-23.
8. Komai H, Adatia IT, Elliott MJ, et al. Increased plasma levels of endothelin-1 after cardiopulmonary bypass in patients with pulmonary hypertension and congenital heart disease. J Thorac Cardiovasc Surg. 1993;106:473-8.
9. Slowinski T, Neumayer HH, Stolze T, et al. Endothelin system in normal and hypertensive pregnancy. Clin Sci. 2002;103:446S-9S.
10. Stamler JS, Loh E, Roddy MA, et al. Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. Circulation. 1994;89:2035-40.
11. Cooper CJ, Jevnikar FW, Walsh T, et al. The influence of basal nitric oxide activity on pulmonary vascular resistance in patients with congestive heart failure. Am J Cardiol. 1998;82:609-14.
12. Cody RJ, Haas GJ, Binkley PF, et al. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-9.
13. Dupuis J, Stewart DJ, Cernacek P, Gosselin G. Human pulmonary circulation is an important site for both clearance and production of endothelin-1. Circulation. 1996;94:1578-84.
14. Boulanger C, Luscher TF. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. J Clin Invest. 1990;85:587-90.
15. Warner TD, Mitchell JA, de Nucci G, Vane JR. Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit. J Cardiovasc Pharmacol. 1989;13:S85-8.
16. Zellers TM, McCormick J, Wu Y. Interaction among ET-1, endothelium-derived nitric oxide, and prostacyclin in pulmonary arteries and veins. Am J Physiol. 1994;267:H139-47.
17. Ahlborg G, Lundberg JM. Nitric oxide-endothelin-1 interaction in humans. J Appl Physiol. 1997;82:1593-600.
18. Dupuis J, Cernacek P, Tardif JC, et al. Reduced pulmonary clearance of endothelin-1 in pulmonary hypertension. Am Heart J. 1998;135:614-20.
19. Wessel DL, Adatia I, Giglia TM, et al. Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass. Circulation. 1993;88:2128-38.
20. Kirshbom PM, Jacobs MT, Tsui SS, et al. Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung. J Thorac Cardiovasc Surg. 1996;111:1248-56.
21. Morita K, Ihnken K, Buckberg GD, et al. Pulmonary vasoconstriction due to impaired nitric oxide production after cardiopulmonary bypass. Ann Thorac Surg. 1996;61:1775-80.
22. Brett SJ, Quinlan GJ, Mitchell J, et al. Production of nitric oxide during surgery involving cardiopulmonary bypass. Crit Care Med. 1998;26:272-8.
23. McMullan DM, Bekker JM, Parry AJ, et al. Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow. Circulation. 2000;102: III172-8.
24. Zhu ZG, Wang MS, Jiang ZB, et al. The dynamic change of plasma endothelin-1 during the perioperative period in patients with rheumatic valvular disease and secondary pulmonary hypertension. J Thorac Cardiovasc Surg. 1994;108:960-8.
25. Wagner F, Dandel M, Günther G, et al. Nitric oxide inhalation in the treatment of right ventricular dysfunction following left ventricular assist device implantation. Circulation. 1997;96:11291-6.
26. Ohkita M, Takaoka M, Shiota Y, et al. Nitric oxide inhibits endothelin-1 production through the suppression of nuclear factor κB. Clin Sci. 2002, 103:68S-71S.
27. Smith AP, Demoncheaux EA, Higgenbottam TW. Nitric oxide gas decreases endothelin-1 mRNA in cultured pulmonary artery endothelial cells. Nitric Oxide 2002;6:153-9.
28. Truog WE, Pallotto E, Clark P, et al. Interaction of endogenous endothelin-1 and inhaled nitric oxide in term and preterm infants. Clin Sci. 2002;103:294S-7S.