Evidence for trichloroethylene bioactivation and adduct formation in the rat epididymis and efferent ducts

Biology of Reproduction

Volumn 69, Issue 3, 2003, Pages 771-779

  DuTeaux, Shelley Brown ^a   Hengel, Matt J ^a   DeGroot, Danica E ^a   Jelks, Karen A ^a   Miller, Marion G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Environment; Epididymis; Male reproductive tract; Toxicology

Indexed keywords

CELL PROTEIN; CYSTEINE CONJUGATE BETA LYASE; CYTOCHROME P450; CYTOCHROME P450 2E1; DICHLOROACETIC ACID; DICHLOROVINYL CYSTEINE; ENZYME ANTIBODY; GLUTATHIONE; TOXIC SUBSTANCE; TRICHLOROETHYLENE; UNCLASSIFIED DRUG; VINYLIDENE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CHEMICAL BINDING; CHEMICAL REACTION; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; EPIDIDYMIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; LIVER INJURY; MACROMOLECULE; MALE; METABOLISM; METABOLITE; MICROSOME; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; RAT; REPRODUCTIVE TOXICITY; SEMINIFEROUS TUBULE; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; WESTERN BLOTTING;

ANIMALS; BIOTRANSFORMATION; CYSTEINE; CYTOCHROME P-450 CYP2E1; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EPIDIDYMIS; IMMUNOHISTOCHEMISTRY; LYASES; MALE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SOLVENTS; TRANSAMINASES; TRICHLOROETHYLENE; VAS DEFERENS;

ANIMALIA;

EID: 0041360238     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.014845     Document Type: Article

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